Detailed information NTG1131647

Bioinformatically predicted

Overview

• Name: endA
• Type: Machinery gene
• Locus tag: H1W90_RS05525
• Genome accession: NZ_LR822033
• Coordinates: 1058155..1059036 (-)
• Length: 293 a.a.
• NCBI ID: WP_011681210.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus isolate STH_CIRM_1048
• Function: cleavage of dsDNA into ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 1053155..1064036

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H1W90_RS05500 (STHERMO_1227)	vicR	1053863..1054570 (-)	708	WP_011226084.1	response regulator YycF	Regulator
H1W90_RS05505 (STHERMO_1228)	-	1055094..1055861 (+)	768	WP_179966655.1	amino acid ABC transporter ATP-binding protein	-
H1W90_RS05510 (STHERMO_1229)	-	1055873..1056706 (+)	834	WP_002953142.1	transporter substrate-binding domain-containing protein	-
H1W90_RS05515 (STHERMO_1230)	-	1056724..1057422 (+)	699	WP_011226087.1	amino acid ABC transporter permease	-
H1W90_RS05520 (STHERMO_1231)	-	1057434..1058084 (+)	651	WP_011226088.1	amino acid ABC transporter permease	-
H1W90_RS05525 (STHERMO_1232)	endA	1058155..1059036 (-)	882	WP_011681210.1	DNA/RNA non-specific endonuclease	Machinery gene
H1W90_RS05530 (STHERMO_1233)	-	1059098..1059286 (-)	189	WP_002953149.1	DNA-directed RNA polymerase subunit beta	-
H1W90_RS05535 (STHERMO_1234)	murA	1059288..1060559 (-)	1272	WP_022096753.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
H1W90_RS05540 (STHERMO_1235)	-	1060629..1060865 (-)	237	WP_002946959.1	DUF1146 family protein	-
H1W90_RS05545 (STHERMO_1236)	galE	1061053..1062066 (-)	1014	WP_002946961.1	UDP-glucose 4-epimerase GalE	-
H1W90_RS05550 (STHERMO_1237)	-	1062081..1062515 (-)	435	WP_232085796.1	DUF4832 domain-containing protein	-

Sequence

Protein

• Length: 293 a.a.
• Molecular weight: 31773.50 Da
• Isoelectric Point: 10.1789

>NTDB_id=1131647 H1W90_RS05525 WP_011681210.1 1058155..1059036(-) (endA) [Streptococcus thermophilus isolate STH_CIRM_1048]
MAKRKTSLTNKQKRQLVTLIIAALIAVLGYLGTSNKLSPDNPIRQVASLVSGKSNKSIKSNGSTNSQSTPQEQLAETVMT
SSVKSQLGNSLEWNGAGAYIINRNKTNLNAKVSSQPYANNQVKTVQGQTVPTVANALLSKATRQYKNRQETGNGSTSWTP
AGWHQVQNLSGEYSHAVDRGHLLGYALIGGLKGFDASTSNPENIAVQTAWANQAYSDSSTGQNYYESLVRKALDKNKRVR
YRVTLIYEGENLIPSGTHLEAKSADGSLEFNVFVPNVQEGITLDYYSGKVTVN

Nucleotide

• Length: 882 bp

>NTDB_id=1131647 H1W90_RS05525 WP_011681210.1 1058155..1059036(-) (endA) [Streptococcus thermophilus isolate STH_CIRM_1048]
ATGGCAAAAAGAAAGACATCTTTGACAAATAAACAGAAACGTCAGTTAGTCACATTAATAATAGCAGCTTTGATAGCTGT
TTTAGGTTACCTAGGAACCAGTAACAAGCTCTCGCCTGATAATCCTATCAGACAAGTAGCAAGCCTAGTTTCAGGGAAAT
CTAACAAATCCATTAAATCTAATGGTTCAACAAATAGTCAGTCTACACCACAAGAGCAGCTTGCTGAGACAGTAATGACT
AGTTCAGTCAAAAGCCAACTGGGTAATTCCTTGGAATGGAATGGAGCTGGGGCCTACATTATTAATAGAAATAAGACGAA
TCTAAATGCTAAGGTATCAAGCCAACCCTATGCTAATAACCAAGTCAAAACGGTTCAAGGACAAACTGTTCCTACAGTTG
CTAATGCCTTATTAAGTAAAGCAACTAGACAGTACAAAAATCGTCAAGAAACAGGGAATGGTTCAACCTCTTGGACACCA
GCTGGATGGCACCAGGTTCAAAATTTATCAGGAGAGTATAGCCATGCCGTAGATAGAGGCCATTTGCTAGGTTATGCACT
GATAGGTGGTTTGAAAGGATTTGATGCCTCGACTTCAAATCCAGAGAATATTGCTGTTCAAACTGCTTGGGCAAATCAAG
CATATAGCGATAGTTCTACAGGCCAAAACTATTATGAAAGCCTAGTACGAAAAGCTCTGGATAAAAACAAACGTGTTCGT
TATCGTGTGACCCTGATTTATGAAGGAGAGAATCTCATTCCATCAGGAACACATCTTGAAGCTAAGTCAGCAGACGGCTC
ACTTGAGTTTAATGTCTTTGTTCCAAATGTACAAGAGGGAATTACACTAGATTACTATTCAGGAAAAGTAACGGTGAATT
GA

Domains

Predicted by InterproScan.

• DNA/RNA non-specific endonuclease (Endonuclease_NS) (101-266)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
endA	Streptococcus pneumoniae Rx1	72.803	81.57	0.594
endA	Streptococcus pneumoniae D39	72.803	81.57	0.594
endA	Streptococcus pneumoniae R6	72.803	81.57	0.594
endA	Streptococcus pneumoniae TIGR4	72.803	81.57	0.594