Detailed information
Bioinformatically predicted
Overview
| Name | amiE | Type | Regulator |
| Locus tag | H1W91_RS06930 | Genome accession | NZ_LR822032 |
| Coordinates | 1328113..1329198 (-) | Length | 361 a.a. |
| NCBI ID | WP_011226304.1 | Uniprot ID | - |
| Organism | Streptococcus thermophilus isolate STH_CIRM_1050 | ||
| Function | internalize XIP (predicted from homology) Competence regulation |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| ICE | 1310237..1382252 | 1328113..1329198 | within | 0 |
Gene organization within MGE regions
Location: 1310237..1382252
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| H1W91_RS06845 (STHERMO_1499) | liaF | 1310245..1310943 (-) | 699 | WP_180477088.1 | cell wall-active antibiotics response protein LiaF | - |
| H1W91_RS10120 (STHERMO_1500) | - | 1311209..1311364 (-) | 156 | WP_232087096.1 | ion channel | - |
| H1W91_RS06855 (STHERMO_1503) | - | 1312097..1313346 (+) | 1250 | Protein_1295 | ISL3 family transposase | - |
| H1W91_RS06860 (STHERMO_1504) | stkP/pknB | 1313420..1315291 (-) | 1872 | WP_011226292.1 | Stk1 family PASTA domain-containing Ser/Thr kinase | Regulator |
| H1W91_RS06865 (STHERMO_1505) | - | 1315291..1316028 (-) | 738 | WP_002946881.1 | Stp1/IreP family PP2C-type Ser/Thr phosphatase | - |
| H1W91_RS06870 (STHERMO_1506) | rsmB | 1316072..1317394 (-) | 1323 | WP_014608533.1 | 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB | - |
| H1W91_RS06875 (STHERMO_1507) | fmt | 1317384..1318319 (-) | 936 | WP_002951411.1 | methionyl-tRNA formyltransferase | - |
| H1W91_RS06880 (STHERMO_1508) | - | 1318337..1320733 (-) | 2397 | WP_176243306.1 | primosomal protein N' | - |
| H1W91_RS06885 (STHERMO_1509) | rpoZ | 1320875..1321189 (-) | 315 | WP_002951415.1 | DNA-directed RNA polymerase subunit omega | - |
| H1W91_RS06890 (STHERMO_1510) | gmk | 1321211..1321840 (-) | 630 | WP_022096878.1 | guanylate kinase | - |
| H1W91_RS06895 (STHERMO_1511) | ftsY | 1322073..1323464 (-) | 1392 | WP_180477090.1 | signal recognition particle-docking protein FtsY | - |
| H1W91_RS06900 (STHERMO_1512) | - | 1323475..1324293 (-) | 819 | WP_011681411.1 | Cof-type HAD-IIB family hydrolase | - |
| H1W91_RS06905 (STHERMO_1513) | - | 1324286..1325080 (-) | 795 | WP_180477091.1 | HAD hydrolase family protein | - |
| H1W91_RS06910 (STHERMO_1514) | - | 1325264..1325641 (+) | 378 | WP_011226300.1 | GntR family transcriptional regulator | - |
| H1W91_RS06915 (STHERMO_1515) | - | 1325646..1326344 (+) | 699 | WP_022096876.1 | ABC transporter ATP-binding protein | - |
| H1W91_RS06920 (STHERMO_1516) | - | 1326356..1327141 (+) | 786 | WP_180477092.1 | ABC transporter permease | - |
| H1W91_RS06925 (STHERMO_1517) | amiF | 1327191..1328120 (-) | 930 | WP_002951426.1 | ATP-binding cassette domain-containing protein | Regulator |
| H1W91_RS06930 (STHERMO_1518) | amiE | 1328113..1329198 (-) | 1086 | WP_011226304.1 | ABC transporter ATP-binding protein | Regulator |
| H1W91_RS06935 (STHERMO_1519) | amiD | 1329208..1330134 (-) | 927 | WP_002946409.1 | oligopeptide ABC transporter permease OppC | Regulator |
| H1W91_RS06940 (STHERMO_1520) | amiC | 1330134..1331627 (-) | 1494 | WP_011227407.1 | ABC transporter permease | Regulator |
| H1W91_RS06945 (STHERMO_1521) | amiA | 1331689..1333656 (-) | 1968 | WP_180477093.1 | peptide ABC transporter substrate-binding protein | Regulator |
| H1W91_RS09700 (STHERMO_1522) | - | 1334012..1335261 (+) | 1250 | Protein_1314 | ISL3 family transposase | - |
| H1W91_RS06955 (STHERMO_1523) | amiA3 | 1335316..1337289 (-) | 1974 | WP_180477094.1 | peptide ABC transporter substrate-binding protein | Regulator |
| H1W91_RS06960 | - | 1337493..1337683 (-) | 191 | Protein_1316 | IS3 family transposase | - |
| H1W91_RS10535 | - | 1337677..1338087 (-) | 411 | Protein_1317 | ATP-binding cassette domain-containing protein | - |
| H1W91_RS10540 (STHERMO_1526) | - | 1338119..1338432 (-) | 314 | Protein_1318 | TatD family hydrolase | - |
| H1W91_RS06980 (STHERMO_1527) | - | 1338778..1339983 (+) | 1206 | WP_011227415.1 | OFA family MFS transporter | - |
| H1W91_RS06985 | - | 1340030..1341384 (-) | 1355 | Protein_1320 | IS3 family transposase | - |
| H1W91_RS06990 (STHERMO_1532) | pta | 1341470..1342453 (-) | 984 | WP_011227420.1 | phosphate acetyltransferase | - |
| H1W91_RS06995 (STHERMO_1533) | - | 1342463..1343362 (-) | 900 | WP_180477095.1 | RluA family pseudouridine synthase | - |
| H1W91_RS07000 (STHERMO_1534) | - | 1343359..1344195 (-) | 837 | WP_065972449.1 | NAD kinase | - |
| H1W91_RS07005 (STHERMO_1535) | - | 1344167..1344841 (-) | 675 | WP_011681427.1 | GTP pyrophosphokinase family protein | - |
| H1W91_RS07010 (STHERMO_1536) | - | 1344937..1345512 (+) | 576 | WP_002951444.1 | CYTH domain-containing protein | - |
| H1W91_RS07015 (STHERMO_1537) | - | 1345877..1346848 (+) | 972 | WP_002951446.1 | ribose-phosphate diphosphokinase | - |
| H1W91_RS07020 (STHERMO_1538) | - | 1346852..1347964 (+) | 1113 | WP_082309052.1 | cysteine desulfurase family protein | - |
| H1W91_RS07025 (STHERMO_1539) | - | 1347966..1348313 (+) | 348 | WP_180477096.1 | DUF1831 domain-containing protein | - |
| H1W91_RS07030 (STHERMO_1540) | - | 1348457..1349116 (+) | 660 | WP_041828288.1 | redox-sensing transcriptional repressor Rex | - |
| H1W91_RS07035 | - | 1349109..1349804 (+) | 696 | Protein_1330 | gamma-glutamyl-gamma-aminobutyrate hydrolase family protein | - |
| H1W91_RS07040 (STHERMO_1543) | radC | 1349857..1350543 (-) | 687 | WP_011226324.1 | RadC family protein | - |
| H1W91_RS07045 (STHERMO_1544) | - | 1350722..1352062 (-) | 1341 | WP_231108743.1 | DUF2142 domain-containing protein | - |
| H1W91_RS07050 (STHERMO_1545) | - | 1352211..1353956 (-) | 1746 | WP_011227426.1 | rhamnan synthesis F family protein | - |
| H1W91_RS07055 (STHERMO_1546) | - | 1353958..1355700 (-) | 1743 | WP_180477097.1 | glycosyltransferase family 4 protein | - |
| H1W91_RS07060 (STHERMO_1547) | - | 1355718..1356920 (-) | 1203 | WP_180477098.1 | ABC transporter ATP-binding protein | - |
| H1W91_RS07065 (STHERMO_1548) | - | 1356920..1357726 (-) | 807 | WP_011227429.1 | ABC transporter permease | - |
| H1W91_RS07070 (STHERMO_1549) | - | 1357726..1358667 (-) | 942 | WP_011227430.1 | glycosyltransferase family 2 protein | - |
| H1W91_RS07075 (STHERMO_1550) | cps2T | 1358664..1359812 (-) | 1149 | WP_011227431.1 | beta 1-4 rhamnosyltransferase Cps2T | - |
| H1W91_RS07080 (STHERMO_1551) | - | 1359931..1360713 (-) | 783 | WP_011227432.1 | glycosyltransferase family A protein | - |
| H1W91_RS07085 (STHERMO_1552) | - | 1360714..1361046 (-) | 333 | WP_011227433.1 | DUF2304 domain-containing protein | - |
| H1W91_RS07090 (STHERMO_1553) | - | 1361052..1361747 (-) | 696 | WP_173405413.1 | glycosyltransferase family 2 protein | - |
| H1W91_RS07095 | - | 1361831..1362303 (-) | 473 | Protein_1342 | glycosyltransferase family 2 protein | - |
| H1W91_RS07100 (STHERMO_1556) | - | 1362368..1363354 (-) | 987 | WP_180477099.1 | glycosyltransferase family 2 protein | - |
| H1W91_RS07105 (STHERMO_1557) | - | 1363351..1364610 (-) | 1260 | WP_180477100.1 | oligosaccharide flippase family protein | - |
| H1W91_RS07110 (STHERMO_1558) | rfbD | 1364731..1365582 (-) | 852 | WP_014621820.1 | dTDP-4-dehydrorhamnose reductase | - |
| H1W91_RS07115 (STHERMO_1559) | - | 1365700..1366626 (-) | 927 | WP_011227439.1 | glycosyltransferase family 2 protein | - |
| H1W91_RS07120 (STHERMO_1560) | - | 1366636..1366971 (-) | 336 | WP_002891474.1 | metal-sulfur cluster assembly factor | - |
| H1W91_RS07125 (STHERMO_1561) | rpoD | 1367025..1368134 (-) | 1110 | WP_179970613.1 | RNA polymerase sigma factor RpoD | - |
| H1W91_RS07130 (STHERMO_1562) | dnaG | 1368138..1369949 (-) | 1812 | WP_180477101.1 | DNA primase | - |
| H1W91_RS07135 (STHERMO_1563) | mscL | 1370089..1370172 (+) | 84 | Protein_1350 | large conductance mechanosensitive channel protein MscL | - |
| H1W91_RS07140 (STHERMO_1564) | rpsU | 1370332..1370508 (-) | 177 | WP_082309068.1 | 30S ribosomal protein S21 | - |
| H1W91_RS07145 (STHERMO_1565) | - | 1370703..1371497 (-) | 795 | WP_180477102.1 | ABC transporter substrate-binding protein | - |
| H1W91_RS07150 (STHERMO_1566) | - | 1371590..1372699 (-) | 1110 | WP_180477103.1 | aminotransferase | - |
| H1W91_RS07155 (STHERMO_1567) | - | 1373046..1373843 (-) | 798 | WP_141326473.1 | transporter substrate-binding domain-containing protein | - |
| H1W91_RS07160 (STHERMO_1568) | - | 1373840..1374670 (-) | 831 | WP_087010081.1 | transporter substrate-binding domain-containing protein | - |
| H1W91_RS07165 (STHERMO_1569) | - | 1374883..1375346 (-) | 464 | Protein_1356 | 8-oxo-dGTP diphosphatase | - |
| H1W91_RS07170 (STHERMO_1570) | uvrB | 1375391..1377382 (-) | 1992 | WP_002953358.1 | excinuclease ABC subunit UvrB | - |
| H1W91_RS07175 (STHERMO_1571) | - | 1377529..1377996 (-) | 468 | WP_084829769.1 | hypothetical protein | - |
| H1W91_RS07180 | - | 1378069..1379005 (-) | 937 | Protein_1359 | CPBP family intramembrane glutamic endopeptidase | - |
| H1W91_RS07185 (STHERMO_1573) | - | 1379204..1381414 (+) | 2211 | WP_011226350.1 | ABC transporter substrate-binding protein/permease | - |
| H1W91_RS07190 (STHERMO_1574) | - | 1381414..1382154 (+) | 741 | WP_002945131.1 | amino acid ABC transporter ATP-binding protein | - |
Sequence
Protein
Download Length: 361 a.a. Molecular weight: 39864.62 Da Isoelectric Point: 4.7435
>NTDB_id=1131592 H1W91_RS06930 WP_011226304.1 1328113..1329198(-) (amiE) [Streptococcus thermophilus isolate STH_CIRM_1050]
MTENKNVILSARDIVVEFDVRDRVLTAIRGVSLDLVEGEVLALVGESGSGKSVLTKTFTGMLEENGRVASGSIDYRGKDL
TKFKSHQDWAAIRGAKIATIFQDPMTSLNPIKTIGSQIIEVIVKHQGKTAKEAKKMAIDYMDKVGIPDAEKRFNEYPFQY
SGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLKEEYGFSVIFITHDLGVVASIADKVAVMYAGEIIE
YATVEEIFYEPCHPYTWSLLSSLPQLADDNGKLFSIPGTPPSLYTPVVGDAFALRSDYALQIDFEEKAPQFQVSDTHWAK
TWLLHEDAPKVDKPAVIQNLHEKILANMGFAHLGDEEEGNA
MTENKNVILSARDIVVEFDVRDRVLTAIRGVSLDLVEGEVLALVGESGSGKSVLTKTFTGMLEENGRVASGSIDYRGKDL
TKFKSHQDWAAIRGAKIATIFQDPMTSLNPIKTIGSQIIEVIVKHQGKTAKEAKKMAIDYMDKVGIPDAEKRFNEYPFQY
SGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLKEEYGFSVIFITHDLGVVASIADKVAVMYAGEIIE
YATVEEIFYEPCHPYTWSLLSSLPQLADDNGKLFSIPGTPPSLYTPVVGDAFALRSDYALQIDFEEKAPQFQVSDTHWAK
TWLLHEDAPKVDKPAVIQNLHEKILANMGFAHLGDEEEGNA
Nucleotide
Download Length: 1086 bp
>NTDB_id=1131592 H1W91_RS06930 WP_011226304.1 1328113..1329198(-) (amiE) [Streptococcus thermophilus isolate STH_CIRM_1050]
ATGACAGAAAATAAAAATGTAATATTATCGGCTCGCGATATCGTCGTGGAATTTGACGTTCGTGACCGTGTTTTGACAGC
TATTCGAGGGGTTTCCCTTGATTTAGTTGAAGGTGAAGTTTTAGCCTTGGTTGGTGAATCTGGTTCAGGAAAATCAGTCT
TGACTAAAACTTTTACAGGGATGCTGGAAGAAAATGGTCGTGTAGCTAGCGGATCTATCGACTACCGTGGCAAAGACTTG
ACTAAATTTAAGAGTCACCAAGATTGGGCAGCTATCCGTGGAGCTAAGATTGCAACTATTTTCCAAGATCCAATGACCAG
TCTTAACCCAATTAAGACTATCGGAAGTCAAATTATTGAAGTTATTGTTAAGCACCAAGGGAAAACAGCCAAGGAAGCTA
AAAAAATGGCAATTGATTACATGGACAAGGTTGGTATTCCAGATGCTGAAAAACGTTTCAATGAATATCCTTTCCAATAC
TCTGGTGGGATGCGTCAACGTATCGTTATTGCCATTGCCTTGGCTTGTCGTCCTGATGTCCTTATCTGTGACGAACCAAC
AACTGCCCTTGATGTGACCATTCAAGCTCAAATCATTGACCTCTTGAAATCACTCAAAGAGGAGTATGGTTTCTCGGTCA
TTTTCATTACCCATGACCTTGGCGTCGTAGCAAGTATCGCGGACAAGGTTGCTGTCATGTATGCTGGCGAAATCATTGAA
TACGCAACTGTTGAGGAAATTTTCTATGAGCCTTGTCATCCATACACGTGGAGCTTGCTTTCAAGTCTGCCACAATTGGC
TGATGATAATGGAAAACTCTTCTCAATTCCAGGGACGCCACCATCACTTTATACACCAGTTGTTGGGGATGCCTTTGCCT
TGCGTTCAGATTATGCTTTGCAGATTGATTTTGAGGAAAAAGCACCACAATTCCAAGTTTCAGATACTCACTGGGCTAAG
ACCTGGCTCTTACATGAGGATGCGCCAAAAGTTGATAAACCTGCGGTTATCCAAAATCTACATGAAAAAATCCTAGCCAA
TATGGGATTTGCACATTTAGGAGATGAGGAGGAAGGCAATGCCTGA
ATGACAGAAAATAAAAATGTAATATTATCGGCTCGCGATATCGTCGTGGAATTTGACGTTCGTGACCGTGTTTTGACAGC
TATTCGAGGGGTTTCCCTTGATTTAGTTGAAGGTGAAGTTTTAGCCTTGGTTGGTGAATCTGGTTCAGGAAAATCAGTCT
TGACTAAAACTTTTACAGGGATGCTGGAAGAAAATGGTCGTGTAGCTAGCGGATCTATCGACTACCGTGGCAAAGACTTG
ACTAAATTTAAGAGTCACCAAGATTGGGCAGCTATCCGTGGAGCTAAGATTGCAACTATTTTCCAAGATCCAATGACCAG
TCTTAACCCAATTAAGACTATCGGAAGTCAAATTATTGAAGTTATTGTTAAGCACCAAGGGAAAACAGCCAAGGAAGCTA
AAAAAATGGCAATTGATTACATGGACAAGGTTGGTATTCCAGATGCTGAAAAACGTTTCAATGAATATCCTTTCCAATAC
TCTGGTGGGATGCGTCAACGTATCGTTATTGCCATTGCCTTGGCTTGTCGTCCTGATGTCCTTATCTGTGACGAACCAAC
AACTGCCCTTGATGTGACCATTCAAGCTCAAATCATTGACCTCTTGAAATCACTCAAAGAGGAGTATGGTTTCTCGGTCA
TTTTCATTACCCATGACCTTGGCGTCGTAGCAAGTATCGCGGACAAGGTTGCTGTCATGTATGCTGGCGAAATCATTGAA
TACGCAACTGTTGAGGAAATTTTCTATGAGCCTTGTCATCCATACACGTGGAGCTTGCTTTCAAGTCTGCCACAATTGGC
TGATGATAATGGAAAACTCTTCTCAATTCCAGGGACGCCACCATCACTTTATACACCAGTTGTTGGGGATGCCTTTGCCT
TGCGTTCAGATTATGCTTTGCAGATTGATTTTGAGGAAAAAGCACCACAATTCCAAGTTTCAGATACTCACTGGGCTAAG
ACCTGGCTCTTACATGAGGATGCGCCAAAAGTTGATAAACCTGCGGTTATCCAAAATCTACATGAAAAAATCCTAGCCAA
TATGGGATTTGCACATTTAGGAGATGAGGAGGAAGGCAATGCCTGA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| amiE | Streptococcus thermophilus LMG 18311 |
100 |
100 |
1 |
| amiE | Streptococcus thermophilus LMD-9 |
100 |
100 |
1 |
| amiE | Streptococcus salivarius strain HSISS4 |
96.953 |
100 |
0.97 |
| oppD | Streptococcus mutans UA159 |
54.441 |
96.676 |
0.526 |