Detailed information NTG1131527

Bioinformatically predicted

Overview

• Name: endA
• Type: Machinery gene
• Locus tag: H1W74_RS05340
• Genome accession: NZ_LR822031
• Coordinates: 1023077..1023958 (-)
• Length: 293 a.a.
• NCBI ID: WP_022096754.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus isolate STH_CIRM_1047
• Function: cleavage of dsDNA into ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 1018077..1028958

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H1W74_RS05315 (STHERMO_1212)	vicR	1018781..1019488 (-)	708	WP_011226084.1	response regulator YycF	Regulator
H1W74_RS05320 (STHERMO_1214)	-	1020015..1020782 (+)	768	WP_022096757.1	amino acid ABC transporter ATP-binding protein	-
H1W74_RS05325 (STHERMO_1215)	-	1020794..1021627 (+)	834	WP_022096756.1	transporter substrate-binding domain-containing protein	-
H1W74_RS05330 (STHERMO_1216)	-	1021645..1022343 (+)	699	WP_022096755.1	amino acid ABC transporter permease	-
H1W74_RS05335 (STHERMO_1217)	-	1022355..1023005 (+)	651	WP_011226088.1	amino acid ABC transporter permease	-
H1W74_RS05340 (STHERMO_1218)	endA	1023077..1023958 (-)	882	WP_022096754.1	DNA/RNA non-specific endonuclease	Machinery gene
H1W74_RS05345 (STHERMO_1219)	-	1024020..1024208 (-)	189	WP_011226090.1	DNA-directed RNA polymerase subunit beta	-
H1W74_RS05350 (STHERMO_1220)	murA	1024210..1025481 (-)	1272	WP_022096753.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
H1W74_RS05355 (STHERMO_1221)	-	1025551..1025787 (-)	237	WP_002946959.1	DUF1146 family protein	-
H1W74_RS05360 (STHERMO_1222)	galE	1025975..1026988 (-)	1014	WP_002946961.1	UDP-glucose 4-epimerase GalE	-
H1W74_RS05365 (STHERMO_1223)	-	1026948..1027619 (-)	672	WP_331251216.1	DUF4832 domain-containing protein	-

Sequence

Protein

• Length: 293 a.a.
• Molecular weight: 31813.61 Da
• Isoelectric Point: 10.1789

>NTDB_id=1131527 H1W74_RS05340 WP_022096754.1 1023077..1023958(-) (endA) [Streptococcus thermophilus isolate STH_CIRM_1047]
MAKRKTSLTNKQKRQLVTLIIAVLIAVLGYLGTSNKLSPDNPIRQVASLVSGKSNKSIKSNGSINSQSTPQEQLAETVMT
SSVKSQLGNSLEWNGAGAYIINRNKTNLNAKVSSQPYANNQVKTVQGQTVPTVANALLSKATRQYKNRQETGNGSTSWTP
AGWHQVQNLSGEYSHAVDRGHLLGYALIGGLKGFDASTSNPENIAVQTAWANQAYSDSSTGQNYYESLVRKALDKNKRVR
YRVTLIYEGENLIPSGTHLEAKSADGSLEFNVFVPNVQEGITLDYYSGKVTVN

Nucleotide

• Length: 882 bp

>NTDB_id=1131527 H1W74_RS05340 WP_022096754.1 1023077..1023958(-) (endA) [Streptococcus thermophilus isolate STH_CIRM_1047]
ATGGCAAAAAGAAAGACATCTTTGACAAATAAACAGAAACGTCAGTTAGTCACATTAATAATAGCAGTTTTGATAGCTGT
TTTAGGTTACCTAGGAACCAGTAACAAGCTCTCGCCTGATAATCCTATCAGACAAGTAGCAAGCCTAGTTTCAGGGAAAT
CTAACAAATCCATTAAATCTAATGGTTCAATAAATAGTCAGTCTACACCACAAGAGCAGCTTGCTGAGACAGTAATGACT
AGTTCAGTCAAAAGCCAACTGGGTAATTCCTTGGAATGGAATGGAGCTGGGGCCTACATTATTAATAGAAATAAGACGAA
TCTAAATGCTAAGGTATCAAGCCAACCCTATGCTAATAACCAAGTCAAAACGGTTCAAGGACAAACTGTTCCTACAGTTG
CTAATGCCTTATTAAGTAAAGCAACTAGACAGTACAAAAATCGTCAAGAAACAGGGAATGGTTCAACCTCTTGGACACCA
GCTGGATGGCACCAGGTTCAAAATTTATCAGGAGAGTATAGCCATGCCGTAGATAGAGGCCATTTGCTAGGTTATGCACT
GATAGGTGGTTTGAAAGGATTTGATGCCTCGACTTCAAATCCAGAGAATATTGCTGTTCAAACTGCTTGGGCAAATCAAG
CATATAGCGATAGTTCTACAGGCCAAAACTATTATGAAAGCCTAGTACGAAAAGCTCTGGATAAAAACAAACGTGTTCGT
TATCGTGTGACCCTGATTTATGAAGGAGAGAATCTCATTCCATCAGGAACACATCTTGAAGCTAAGTCAGCAGACGGCTC
ACTTGAGTTTAATGTCTTTGTTCCAAATGTACAAGAGGGAATTACACTAGATTACTATTCAGGAAAAGTAACGGTGAATT
GA

Domains

Predicted by InterproScan.

• DNA/RNA non-specific endonuclease (Endonuclease_NS) (101-266)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
endA	Streptococcus pneumoniae Rx1	70.635	86.007	0.608
endA	Streptococcus pneumoniae D39	70.635	86.007	0.608
endA	Streptococcus pneumoniae R6	70.635	86.007	0.608
endA	Streptococcus pneumoniae TIGR4	70.635	86.007	0.608