Detailed information    

insolico Bioinformatically predicted

Overview

Name   covS   Type   Regulator
Locus tag   H1W74_RS01575 Genome accession   NZ_LR822031
Coordinates   290277..291794 (+) Length   505 a.a.
NCBI ID   WP_022096582.1    Uniprot ID   -
Organism   Streptococcus thermophilus isolate STH_CIRM_1047     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 285277..296794
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H1W74_RS01550 (STHERMO_0330) - 285744..286415 (-) 672 WP_002946492.1 potassium channel family protein -
  H1W74_RS01555 (STHERMO_0331) - 286455..287819 (-) 1365 WP_002946491.1 TrkH family potassium uptake protein -
  H1W74_RS01560 (STHERMO_0332) rsmG 287889..288602 (-) 714 WP_002946490.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  H1W74_RS01565 (STHERMO_0333) - 288899..289435 (+) 537 WP_002946488.1 DUF177 domain-containing protein -
  H1W74_RS01570 (STHERMO_0334) covR 289591..290280 (+) 690 WP_022096581.1 response regulator transcription factor Regulator
  H1W74_RS01575 (STHERMO_0335) covS 290277..291794 (+) 1518 WP_022096582.1 HAMP domain-containing histidine kinase Regulator
  H1W74_RS01580 (STHERMO_0336) nrdR 291916..292395 (+) 480 WP_002949642.1 transcriptional regulator NrdR -
  H1W74_RS01585 (STHERMO_0337) - 292392..293567 (+) 1176 WP_002949643.1 DnaD domain protein -
  H1W74_RS01590 (STHERMO_0338) dnaI 293571..294473 (+) 903 WP_002946786.1 primosomal protein DnaI -
  H1W74_RS01595 (STHERMO_0339) der 294579..295889 (+) 1311 WP_002946789.1 ribosome biogenesis GTPase Der -

Sequence

Protein


Download         Length: 505 a.a.        Molecular weight: 57580.94 Da        Isoelectric Point: 5.1731

>NTDB_id=1131510 H1W74_RS01575 WP_022096582.1 290277..291794(+) (covS) [Streptococcus thermophilus isolate STH_CIRM_1047]
MSKLFGKVTIRKKLTMTTAVVFFLVLSMFTLVVVFSANTLLLQRERQNVNNTISKVVTYIEKDWDSDEELSPEPLLAALY
SPKNIYPSIINGVLSEKRSLDGQVAVSNRLYSNQSVYVYDKKGTFIFTSEEDTDSPPGMSEVNKLKLVSYKGKRGFLLQV
PIYGKDKKTIVGYAQVFHDLEFYYALKERLIFLLIFLEVGMTVLVIAVTVVVLTSILRPMRQLHETMGIIIDSPSDLELR
SKIESHDEIGDLALNFNCMMDKIQENNQMQMRFLSDVSHELRTPIAVIKGHMDLLQRWGKNDPEILEESLEAASHEANRM
TIMINDMLDSIRVKGSFDNHRNDTCDLNSSIRTVIGNFRVLHDDYQFYLNDSEGSDRPAQIYSQHFEQVITILIDNAVKY
SPVNKKIQITIKALEDEMLVQVQDNGEGISKEDIEHIFERFYRSDKARNRTTTQSGVGIGLSILYQIVEAYRCHIDVSSE
LGVGTRFDLYIPFAESETTTPQIEG

Nucleotide


Download         Length: 1518 bp        

>NTDB_id=1131510 H1W74_RS01575 WP_022096582.1 290277..291794(+) (covS) [Streptococcus thermophilus isolate STH_CIRM_1047]
ATGAGTAAATTATTTGGTAAAGTAACCATTAGAAAAAAGTTGACCATGACAACTGCTGTGGTCTTCTTTCTTGTATTGTC
GATGTTCACTCTGGTTGTTGTATTTTCAGCCAATACGCTTCTTTTGCAACGTGAACGTCAAAATGTAAATAATACAATCT
CAAAAGTTGTTACTTATATCGAAAAGGACTGGGACTCTGATGAAGAGTTGAGTCCAGAGCCGCTTTTAGCGGCCCTTTAT
TCACCGAAAAATATCTATCCATCAATCATTAATGGAGTGCTTTCTGAAAAGCGTTCCTTAGATGGTCAAGTTGCGGTTTC
TAATAGATTATATTCCAACCAGTCTGTCTATGTTTATGACAAAAAGGGAACTTTTATCTTTACTTCTGAGGAGGATACAG
ACTCACCTCCAGGCATGTCTGAGGTCAATAAACTGAAGTTGGTTTCCTATAAAGGTAAACGTGGTTTCTTACTACAAGTT
CCAATCTATGGCAAGGATAAGAAGACCATTGTTGGGTATGCTCAAGTTTTCCATGATTTGGAATTCTACTATGCGTTAAA
AGAGCGTTTAATTTTCCTATTGATATTCCTTGAAGTAGGAATGACGGTCTTAGTTATTGCAGTAACTGTAGTTGTCTTGA
CATCTATTCTTCGTCCGATGAGGCAGTTACACGAAACGATGGGTATTATTATCGATTCGCCAAGTGATTTGGAGCTTCGA
TCTAAGATTGAGAGTCATGATGAGATTGGTGATTTGGCACTTAACTTTAACTGTATGATGGATAAAATTCAAGAAAATAA
TCAGATGCAGATGCGTTTCTTGAGTGACGTCAGTCACGAATTACGTACTCCCATTGCAGTTATTAAAGGACATATGGACC
TCTTGCAACGTTGGGGTAAAAATGATCCTGAAATCCTTGAAGAAAGTCTTGAAGCTGCAAGTCACGAAGCCAACCGTATG
ACGATTATGATTAACGATATGTTGGATTCTATTCGTGTTAAAGGGTCATTTGACAATCATAGAAATGATACATGTGATTT
GAATTCTTCAATCCGTACGGTTATTGGGAATTTTCGTGTCCTACATGACGACTACCAATTCTACCTCAATGATTCTGAGG
GTTCAGATCGTCCAGCACAGATTTACAGCCAGCACTTTGAACAGGTTATTACTATTTTGATTGATAATGCGGTCAAGTAT
TCGCCTGTTAATAAGAAAATCCAGATTACTATCAAGGCTCTGGAAGATGAGATGCTGGTACAGGTACAGGATAATGGTGA
GGGTATCTCTAAAGAAGATATTGAACATATATTTGAACGCTTCTATCGTTCAGATAAGGCGCGTAATCGTACGACAACCC
AATCTGGTGTGGGTATTGGTTTATCAATCCTCTATCAAATTGTGGAAGCTTATCGATGCCATATCGATGTCAGTTCAGAA
CTTGGTGTGGGTACACGTTTTGACCTCTACATTCCTTTTGCAGAGTCAGAAACTACGACACCTCAAATTGAAGGTTAA

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(384-494)

ArlS sensor domain (ArlS_N)

(39-187)

His Kinase A (phospho-acceptor) domain (HisKA)

(270-329)

HAMP domain (HAMP)

(213-265)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covS Streptococcus salivarius strain HSISS4

94.821

99.406

0.943

Multiple sequence alignment