Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYH   Type   Machinery gene
Locus tag   H1X63_RS09310 Genome accession   NZ_LR822027
Coordinates   1804171..1805127 (-) Length   318 a.a.
NCBI ID   WP_179972341.1    Uniprot ID   A0A7U7CBK4
Organism   Streptococcus thermophilus isolate STH_CIRM_998     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1799171..1810127
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H1X63_RS09285 (STHERMO_2036) pepA 1799382..1800449 (+) 1068 WP_180487765.1 glutamyl aminopeptidase -
  H1X63_RS09290 (STHERMO_2037) proC 1800465..1801235 (+) 771 WP_179972337.1 pyrroline-5-carboxylate reductase -
  H1X63_RS09295 (STHERMO_2038) - 1801265..1801927 (-) 663 WP_179972338.1 CPBP family intramembrane glutamic endopeptidase -
  H1X63_RS11290 (STHERMO_2040) - 1802024..1802465 (-) 442 Protein_1773 CAAX protease -
  H1X63_RS09300 (STHERMO_2041) - 1802477..1802674 (-) 198 WP_179972339.1 helix-turn-helix transcriptional regulator -
  H1X63_RS09305 (STHERMO_2042) - 1802922..1804115 (-) 1194 WP_179972340.1 acetate kinase -
  H1X63_RS09310 (STHERMO_2043) comYH 1804171..1805127 (-) 957 WP_179972341.1 class I SAM-dependent methyltransferase Machinery gene
  H1X63_RS09315 (STHERMO_2044) comGG 1805178..1805489 (-) 312 WP_179972342.1 competence type IV pilus minor pilin ComGG -
  H1X63_RS09320 (STHERMO_2045) comYF 1805467..1805904 (-) 438 WP_179972343.1 competence type IV pilus minor pilin ComGF Machinery gene
  H1X63_RS09325 (STHERMO_2046) comGE 1805888..1806181 (-) 294 WP_179972344.1 competence type IV pilus minor pilin ComGE -
  H1X63_RS09330 (STHERMO_2047) comGD 1806153..1806581 (-) 429 WP_269473123.1 competence type IV pilus minor pilin ComGD -
  H1X63_RS09335 (STHERMO_2048) comYC 1806541..1806867 (-) 327 WP_179972346.1 competence type IV pilus major pilin ComGC Machinery gene
  H1X63_RS09340 (STHERMO_2049) comYB 1806864..1807964 (-) 1101 WP_179973355.1 competence type IV pilus assembly protein ComGB Machinery gene
  H1X63_RS09345 (STHERMO_2050) comGA/cglA/cilD 1807846..1808787 (-) 942 WP_179972347.1 competence type IV pilus ATPase ComGA Machinery gene
  H1X63_RS09350 (STHERMO_2051) - 1808868..1809230 (-) 363 WP_179972348.1 DUF1033 family protein -

Sequence

Protein


Download         Length: 318 a.a.        Molecular weight: 35987.11 Da        Isoelectric Point: 4.6574

>NTDB_id=1131369 H1X63_RS09310 WP_179972341.1 1804171..1805127(-) (comYH) [Streptococcus thermophilus isolate STH_CIRM_998]
MNFEAIETAFELLLENVQTIENDLGTHAYDALIEQNSYYLGAEVANELIIKNNEKLRALNLSKEEWRRAFQFLFIKLGQL
EALQANHQFTPDAIGFIILYLLEGLTQEKQLDILEIGSGTGNLAETLLNNTQRTLNYMGMEVDDLLIDLSASIAEVVNSV
AVYIQEDAVRPHILKESNVIISDLPIGYYPNDEIASRFKVAATGEHTYAHHLLMEQSLKYLKKDGIAIFLAPTNLLTSPQ
SDLLKKWLSGYADIIAVITLPEAAFSNKHNMKSIFVLKKQTKNAPETFVYPLSDLQNPRVLKDFTENFQKWKSDNSIF

Nucleotide


Download         Length: 957 bp        

>NTDB_id=1131369 H1X63_RS09310 WP_179972341.1 1804171..1805127(-) (comYH) [Streptococcus thermophilus isolate STH_CIRM_998]
ATGAATTTTGAAGCAATTGAGACAGCTTTTGAGCTGTTGTTAGAAAATGTCCAAACTATTGAAAATGATCTTGGAACCCA
TGCTTACGATGCACTTATTGAGCAAAATTCCTATTATTTGGGGGCTGAGGTTGCTAATGAGCTCATCATCAAAAACAACG
AGAAATTACGGGCGCTTAATCTAAGTAAAGAGGAGTGGCGTCGTGCTTTTCAGTTTTTGTTTATCAAACTAGGGCAATTG
GAAGCTTTACAAGCCAATCACCAATTTACACCAGATGCTATCGGATTTATCATTCTGTACTTGCTCGAAGGTTTGACCCA
GGAAAAACAATTGGATATCTTGGAGATTGGTTCGGGAACAGGGAACTTGGCTGAAACTCTTCTAAATAATACTCAGAGAA
CCCTTAATTATATGGGGATGGAAGTTGATGATCTTCTTATCGATTTGTCAGCTAGTATTGCTGAGGTGGTAAATTCAGTA
GCGGTTTATATCCAAGAGGATGCTGTTCGACCACATATTCTCAAAGAGAGTAACGTTATTATCAGCGATTTACCTATAGG
TTACTACCCTAATGATGAGATTGCGAGTCGTTTCAAGGTGGCAGCAACCGGCGAACACACTTATGCCCATCATCTTCTTA
TGGAGCAATCGCTTAAGTATTTGAAGAAAGATGGTATTGCTATTTTTTTGGCACCAACCAATCTTTTGACAAGCCCTCAA
AGTGATCTGCTTAAGAAGTGGTTATCAGGATATGCTGATATTATTGCTGTTATTACTCTTCCAGAAGCAGCTTTTAGCAA
TAAACATAACATGAAGTCTATCTTTGTGCTAAAAAAACAAACTAAAAATGCTCCTGAGACCTTCGTTTACCCACTTAGCG
ATTTGCAAAATCCAAGGGTCCTCAAGGATTTTACAGAGAATTTCCAAAAATGGAAATCAGATAATTCCATTTTCTAG

Domains

Predicted by InterproScan.

N-6 DNA Methylase (N6_Mtase)

(69-293)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7CBK4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYH Streptococcus mutans UA159

68.889

99.057

0.682
  comYH Streptococcus mutans UA140

68.889

99.057

0.682

Multiple sequence alignment