Detailed information    

insolico Bioinformatically predicted

Overview

Name   sepM   Type   Regulator
Locus tag   H1X63_RS08120 Genome accession   NZ_LR822027
Coordinates   1569082..1570158 (-) Length   358 a.a.
NCBI ID   WP_179972223.1    Uniprot ID   A0A7U7C886
Organism   Streptococcus thermophilus isolate STH_CIRM_998     
Function   processing of CSP (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
IScluster/Tn 1567684..1568631 1569082..1570158 flank 451


Gene organization within MGE regions


Location: 1567684..1570158
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H1X63_RS10800 - 1567732..1568988 (+) 1257 Protein_1539 ISL3 family transposase -
  H1X63_RS08120 (STHERMO_1772) sepM 1569082..1570158 (-) 1077 WP_179972223.1 SepM family pheromone-processing serine protease Regulator

Sequence

Protein


Download         Length: 358 a.a.        Molecular weight: 39237.27 Da        Isoelectric Point: 9.7882

>NTDB_id=1131363 H1X63_RS08120 WP_179972223.1 1569082..1570158(-) (sepM) [Streptococcus thermophilus isolate STH_CIRM_998]
MANKTKSKSLLEKMWRIKWWLLSIFTLLFLLFALFFPLNNYYVELPGGAFDTKEVLTVNKKADDSKGSYNFVAVAQTKAT
LALMLYAKFNDFAKLQTAEEATGNYSDEDFIRINKFYMETSQNQAVYQGLTLAGKEVSLKYMGVYVLQVADDSSFKGVLN
IADTVTAVNGKTFDNSTDMIKYVQGLKLGSKVKVTYMRDGKEKTATGKIIKIANGKNGIGIGLTDHTEIKSPENVKFKLD
GVGGPSAGLIFTLAIYDQVSGQDLKAGRKIAGTGTIEKDGTVGDIGGAYLKVKSAADSGADIFFVPNNLVTKEMKKVDPD
AKTNYQEAKEAAEKLGTKMKIVPVKTAQEAIDYLKKTK

Nucleotide


Download         Length: 1077 bp        

>NTDB_id=1131363 H1X63_RS08120 WP_179972223.1 1569082..1570158(-) (sepM) [Streptococcus thermophilus isolate STH_CIRM_998]
GTGGCAAACAAGACAAAATCTAAATCGCTACTAGAGAAAATGTGGCGTATTAAGTGGTGGTTATTAAGTATTTTTACGTT
ACTTTTCCTCCTTTTTGCCCTCTTTTTCCCTCTCAATAATTACTATGTGGAGCTTCCGGGTGGTGCTTTTGATACCAAGG
AAGTCTTGACAGTGAATAAGAAAGCTGATGATTCTAAGGGCTCCTATAATTTTGTGGCGGTGGCTCAAACCAAGGCGACT
TTGGCCTTGATGCTCTATGCTAAGTTTAATGATTTTGCAAAGCTTCAAACGGCTGAAGAGGCAACTGGAAATTACTCTGA
TGAAGATTTCATACGCATCAACAAATTTTACATGGAGACTTCTCAAAACCAAGCGGTTTATCAGGGCTTGACTCTGGCTG
GTAAGGAGGTTAGTTTGAAGTATATGGGTGTCTATGTGCTTCAGGTTGCTGATGATTCTAGCTTCAAGGGTGTCCTCAAT
ATCGCTGATACGGTGACGGCTGTTAATGGTAAGACCTTTGATAATTCGACTGACATGATTAAATACGTTCAAGGACTTAA
GCTGGGTTCAAAGGTCAAGGTCACTTATATGAGAGATGGTAAAGAAAAGACTGCTACTGGTAAGATTATTAAGATTGCCA
ATGGCAAAAATGGTATTGGTATCGGCCTAACGGACCATACTGAAATTAAGAGTCCTGAGAATGTTAAGTTTAAACTAGAT
GGTGTCGGTGGGCCAAGTGCTGGTCTTATATTTACCTTGGCTATTTACGATCAGGTGTCTGGTCAAGACCTCAAGGCTGG
CCGCAAGATTGCTGGTACAGGAACTATTGAAAAAGATGGGACTGTCGGTGATATCGGTGGGGCCTATCTCAAGGTGAAAT
CTGCGGCTGATAGTGGCGCAGACATTTTCTTCGTGCCAAATAATCTAGTAACTAAGGAAATGAAAAAGGTCGATCCGGAT
GCCAAGACTAATTATCAAGAGGCCAAGGAAGCTGCCGAGAAACTGGGCACCAAGATGAAAATCGTCCCTGTTAAAACAGC
TCAAGAAGCCATTGATTATTTGAAAAAGACTAAATGA

Domains

Predicted by InterproScan.

Lon protease (S16) C-terminal proteolytic domain (Lon_C)

(244-321)

PDZ domain (PDZ_2)

(140-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7C886

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sepM Streptococcus mutans UA159

62.463

95.251

0.595

Multiple sequence alignment