Detailed information NTG1131317

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: H1X63_RS00520
• Genome accession: NZ_LR822027
• Coordinates: 85837..88287 (+)
• Length: 816 a.a.
• NCBI ID: WP_179973245.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus isolate STH_CIRM_998
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 80837..93287

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H1X63_RS00490 (STHERMO_0075)	-	81147..82100 (-)	954	Protein_60	S66 family peptidase	-
H1X63_RS00500 (STHERMO_0076)	rpsB	82623..83390 (+)	768	WP_084830432.1	30S ribosomal protein S2	-
H1X63_RS00505 (STHERMO_0077)	tsf	83502..84542 (+)	1041	WP_084830433.1	translation elongation factor Ts	-
H1X63_RS00510 (STHERMO_0078)	-	84652..85122 (-)	471	WP_100285118.1	COG2426 family protein	-
H1X63_RS00515 (STHERMO_0080)	-	85366..85836 (+)	471	WP_179972491.1	CtsR family transcriptional regulator	-
H1X63_RS00520 (STHERMO_0081)	clpC	85837..88287 (+)	2451	WP_179973245.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
H1X63_RS00525 (STHERMO_0082)	pbp3	88415..89671 (-)	1257	WP_179972493.1	D-alanyl-D-alanine carboxypeptidase PBP3	-
H1X63_RS00530 (STHERMO_0083)	pbp3	89816..91063 (-)	1248	WP_179972494.1	D-alanyl-D-alanine carboxypeptidase PBP3	-

Sequence

Protein

• Length: 816 a.a.
• Molecular weight: 90442.61 Da
• Isoelectric Point: 5.6117

>NTDB_id=1131317 H1X63_RS00520 WP_179973245.1 85837..88287(+) (clpC) [Streptococcus thermophilus isolate STH_CIRM_998]
MTIYSRKMQAIFHRAQLEAERFESPFLETWHVLLAMVEVPGSVAYLTFTDFEDRIHSEEIETAAVLAMEKRPKDLSESDI
IDLRAQSPALEAMLQEAQGIASVTGAVEVGSEHVLMAFLLHKDLMVCRLLEVAGFQYKDDSDKPRIIDLRRSLERNAGLS
KQDLKAIHDLRKPKKSKASGNFANMMQPPQSSTGELADYTKDLTALAESGNLDPVIGRDEEISRMIQVLSRKTKNNPVLV
GEAGVGKTALALGLAQRIASGEVPFELADMRILELDMMSVVAGTRFRGDFEERMNQIIDEIEADGKIILFIDELHTIIGS
GSGIDSTLDAANILKPALARGTLHMVGATTQAEYQKHIEKDAALSRRFAKITIEEPSVSEAIDILNGLRSSYEDYHRVTI
TDEAVETAVKAAHRYLTSKNLPDSAIDLLDEASATVQVRIKKEAKREITPLDEALLSGDIRAAVEQYKANQKAKFPKPAL
VDADQIMQTLSRLSGIPVEKMTQTDSKRYLNLESELHKRVIGQDEAVSVISRAIRRNQSGIRTGKRPIGSFMFLGPTGVG
KTELAKALAEVLFDDESALLRFDMSEYMEKFAASRLNGAPPGYVGYDEGGELTEKVRNKPYSVLLFDEIEKAHPDIFNVL
LQVLDDGVLTDSRGRKVDFSNTIIIMTSNLGATALRDDKTVGFGAQTISHNHQAMQARIMEELKKSYRPEFINRIDEKVV
FHSLEEEQLHDIVKIMVKPLISALADKGISLKFQPAALKHLAKDGYDIEMGARPLRRTIQTQVEDKLSELLLGGQVVSGQ
TLKIGCSKDKLTFTVV

Nucleotide

• Length: 2451 bp

>NTDB_id=1131317 H1X63_RS00520 WP_179973245.1 85837..88287(+) (clpC) [Streptococcus thermophilus isolate STH_CIRM_998]
ATGACGATATATTCAAGAAAAATGCAGGCCATTTTCCATCGTGCTCAGCTTGAAGCGGAGCGTTTTGAAAGTCCTTTCTT
GGAGACTTGGCATGTGCTTCTGGCTATGGTTGAGGTTCCGGGATCTGTAGCCTACTTAACATTTACTGATTTTGAGGACC
GTATTCATTCAGAAGAGATTGAGACAGCTGCTGTATTGGCTATGGAGAAGAGGCCAAAAGACTTGTCGGAATCAGATATT
ATCGATTTACGTGCACAGTCACCTGCGCTAGAGGCTATGTTGCAAGAGGCGCAAGGAATCGCTAGTGTGACTGGTGCTGT
AGAGGTAGGGTCTGAACATGTATTGATGGCCTTCCTTCTTCATAAGGATTTAATGGTTTGTCGCCTCCTTGAAGTGGCTG
GTTTTCAATATAAAGATGATAGCGATAAACCTCGCATCATAGATTTACGACGTTCTTTGGAGCGTAATGCTGGTCTTAGC
AAGCAAGATTTGAAGGCAATTCACGATCTTCGTAAACCTAAGAAATCAAAAGCATCTGGGAATTTTGCCAATATGATGCA
ACCTCCTCAATCATCTACTGGTGAACTGGCAGATTATACCAAAGACTTAACTGCATTAGCGGAGTCAGGAAATCTTGATC
CCGTTATTGGACGCGATGAAGAAATTTCACGCATGATCCAGGTTTTGAGTCGTAAAACGAAGAATAATCCCGTCTTGGTA
GGTGAAGCTGGTGTCGGTAAGACAGCACTTGCTCTTGGTTTAGCGCAACGTATTGCTTCAGGCGAAGTACCATTTGAATT
GGCTGATATGCGTATCTTAGAGCTTGACATGATGAGCGTTGTTGCAGGGACACGTTTCCGTGGTGATTTCGAAGAGCGTA
TGAATCAGATTATTGATGAGATTGAAGCTGATGGGAAAATCATTCTCTTTATTGACGAACTACATACGATTATTGGATCT
GGTTCAGGTATTGATAGTACCTTGGACGCGGCTAATATTTTGAAACCGGCCCTTGCGCGCGGGACACTTCACATGGTTGG
AGCAACCACGCAAGCTGAATACCAAAAGCATATTGAGAAAGATGCGGCTTTATCCCGTCGTTTTGCTAAAATTACAATTG
AAGAACCAAGTGTATCTGAAGCAATCGATATTTTAAACGGTTTGCGTTCGTCTTATGAAGACTATCATCGTGTGACAATT
ACGGACGAGGCAGTTGAGACGGCAGTCAAGGCAGCGCATCGCTATTTGACGAGTAAGAATTTGCCTGATTCGGCAATTGA
TCTTTTAGATGAAGCGAGTGCAACTGTTCAAGTTCGTATCAAAAAAGAGGCCAAACGTGAGATAACACCTTTGGATGAAG
CACTTCTATCTGGGGATATTAGGGCTGCTGTTGAACAGTACAAGGCTAATCAAAAGGCAAAATTTCCTAAACCTGCTTTG
GTAGATGCGGATCAGATTATGCAAACTCTTAGTCGTTTATCAGGTATCCCTGTTGAGAAGATGACGCAGACTGACAGCAA
GCGTTACCTGAATCTTGAATCAGAACTCCACAAACGTGTTATTGGTCAAGATGAGGCAGTTTCGGTTATCAGCCGTGCTA
TTCGTCGTAATCAGTCAGGTATTCGTACTGGAAAACGTCCTATTGGCTCCTTCATGTTCCTTGGACCTACTGGTGTTGGT
AAGACAGAATTGGCCAAGGCTTTGGCGGAAGTTCTCTTTGATGATGAATCAGCTTTGCTTCGCTTTGATATGTCGGAATA
TATGGAAAAATTTGCGGCTAGTCGCCTTAATGGTGCTCCTCCAGGGTATGTCGGATATGATGAGGGTGGAGAGCTGACAG
AGAAAGTTCGAAATAAGCCCTACTCAGTTCTTCTCTTTGACGAGATTGAGAAAGCTCACCCAGATATCTTCAACGTTCTC
TTACAGGTTTTGGATGACGGTGTTTTAACAGATAGCCGTGGTCGTAAGGTTGATTTTTCAAACACTATCATCATTATGAC
CTCAAATTTGGGAGCTACAGCTCTTCGTGATGATAAAACTGTTGGTTTTGGTGCTCAAACTATTTCTCATAATCACCAAG
CCATGCAAGCACGCATTATGGAAGAGCTTAAGAAGTCCTATCGTCCAGAATTTATTAACCGTATTGATGAGAAGGTTGTC
TTCCACAGCTTAGAGGAAGAACAACTACATGACATTGTCAAGATTATGGTTAAACCATTAATTTCAGCTCTAGCCGATAA
AGGTATAAGCTTAAAATTCCAACCAGCTGCTCTTAAGCATTTGGCTAAGGATGGCTATGATATTGAGATGGGAGCTCGTC
CATTACGTCGTACGATTCAAACTCAAGTGGAGGACAAGTTGTCTGAGTTATTACTAGGTGGCCAAGTTGTTAGCGGACAG
ACCCTTAAGATTGGTTGCTCGAAAGATAAATTAACCTTTACAGTAGTGTAA

Domains

Predicted by InterproScan.

• ATPase family associated with various cellular activities (AAA) (AAA) (238-370)

• AAA domain (Cdc48 subfamily) (AAA_2) (546-717)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (724-804)

• AAA lid domain (AAA_lid_9) (377-456)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (107-135)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (15-46)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Streptococcus thermophilus LMG 18311	99.142	100	0.991
clpC	Streptococcus thermophilus LMD-9	98.775	100	0.988
clpC	Streptococcus mutans UA159	72.304	100	0.723
clpC	Streptococcus pneumoniae TIGR4	66.216	99.755	0.661
clpC	Streptococcus pneumoniae Rx1	66.216	99.755	0.661
clpC	Streptococcus pneumoniae D39	66.216	99.755	0.661
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	50.06	100	0.51
clpC	Bacillus subtilis subsp. subtilis str. 168	47.138	100	0.474
clpE	Streptococcus mutans UA159	47.604	76.716	0.365