Detailed information    

insolico Bioinformatically predicted

Overview

Name   covS   Type   Regulator
Locus tag   H0514_RS08475 Genome accession   NZ_LR822020
Coordinates   1646881..1648398 (-) Length   505 a.a.
NCBI ID   WP_179972619.1    Uniprot ID   -
Organism   Streptococcus thermophilus isolate STH_CIRM_956     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1641881..1653398
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H0514_RS08450 - 1642054..1642722 (-) 669 Protein_1629 HI_0552 family protein -
  H0514_RS08455 (STHERMO_1949) der 1642786..1644096 (-) 1311 WP_100284866.1 ribosome biogenesis GTPase Der -
  H0514_RS08460 (STHERMO_1950) dnaI 1644202..1645104 (-) 903 WP_100284865.1 primosomal protein DnaI -
  H0514_RS08465 (STHERMO_1951) - 1645108..1646283 (-) 1176 WP_179972621.1 DnaD domain protein -
  H0514_RS08470 (STHERMO_1952) nrdR 1646280..1646759 (-) 480 WP_179972620.1 transcriptional regulator NrdR -
  H0514_RS08475 (STHERMO_1953) covS 1646881..1648398 (-) 1518 WP_179972619.1 HAMP domain-containing histidine kinase Regulator
  H0514_RS08480 (STHERMO_1954) covR 1648395..1649084 (-) 690 WP_179972618.1 response regulator transcription factor Regulator
  H0514_RS08485 (STHERMO_1955) - 1649240..1649776 (-) 537 WP_179972978.1 DUF177 domain-containing protein -
  H0514_RS08490 (STHERMO_1956) rsmG 1650073..1650786 (+) 714 WP_179972617.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  H0514_RS08495 (STHERMO_1957) - 1650856..1652220 (+) 1365 WP_100284859.1 TrkH family potassium uptake protein -
  H0514_RS08500 (STHERMO_1958) - 1652260..1652931 (+) 672 WP_100284858.1 potassium channel family protein -
  H0514_RS10920 (STHERMO_1959) - 1652969..1653120 (-) 152 Protein_1640 ascorbate 6-phosphate lactonase -

Sequence

Protein


Download         Length: 505 a.a.        Molecular weight: 57469.79 Da        Isoelectric Point: 5.0789

>NTDB_id=1131109 H0514_RS08475 WP_179972619.1 1646881..1648398(-) (covS) [Streptococcus thermophilus isolate STH_CIRM_956]
MSKLFGKVTIRKKLTMTTAVVFFLVLSMFTLVVVFSANTLLLQRERQNVNNTISKVVTYIEKDWDSDEELSPEPLLAALY
SPKNIYSSIINGVLSEKRSLDGQVAVSNKLYSNQSVYVYDKKGTFIFTSEEDTDSPPGMSEVNKLKLVSYKGKRGFLLQV
PIYGKDKNTIVGYAQVFHDLEFYYALKERLIFLLIFLEVGMTVLVIAVTIVVLTSILRPMRQLHETMGIIIDSPSDLELR
SKIGSHDEIGALALNFNCMMDKIQENNQMQMRFLSDVSHELRTPIAVIKGHMDLLQRWGKNDPEILEESLEAASHEANRM
TIMINDMLDSIRVKGSFDNHRNDTCDLNSSIRTVIGNFRVLHDDYQFYLNDSESLDRPAQIYSQHFEQVITILIDNAVKY
SPVNKEIQITIKALEDEMLVQVQDNGEGISKEDIEHIFERFYRSDKARNRTTTQSGVGIGLSILYQIVEAYRCHIDVSSE
LGVGTRFDLYIPFADSETTTPQLEG

Nucleotide


Download         Length: 1518 bp        

>NTDB_id=1131109 H0514_RS08475 WP_179972619.1 1646881..1648398(-) (covS) [Streptococcus thermophilus isolate STH_CIRM_956]
ATGAGTAAATTATTTGGTAAAGTAACCATTAGAAAAAAGTTGACCATGACAACTGCTGTGGTCTTCTTTCTTGTATTGTC
GATGTTCACTCTGGTTGTTGTATTTTCAGCCAATACGCTTCTTTTGCAACGTGAACGTCAAAATGTAAATAATACAATCT
CAAAAGTTGTTACTTATATCGAAAAGGACTGGGACTCTGATGAAGAGTTGAGTCCAGAACCGCTTTTAGCGGCCCTCTAT
TCACCGAAAAATATCTATTCATCAATCATTAATGGAGTGCTTTCTGAAAAGCGTTCCTTAGATGGTCAAGTTGCGGTTTC
TAATAAATTATATTCTAACCAGTCTGTCTATGTTTATGACAAAAAGGGAACTTTTATCTTTACTTCTGAGGAGGATACAG
ACTCACCTCCAGGTATGTCTGAGGTCAATAAACTGAAGTTGGTTTCCTATAAAGGTAAACGTGGTTTCTTACTACAAGTT
CCAATCTATGGCAAGGATAAGAATACCATTGTTGGGTATGCTCAAGTTTTCCATGATTTGGAATTCTACTATGCGTTAAA
AGAGCGTCTAATTTTCCTATTGATATTCCTTGAAGTAGGAATGACGGTCTTAGTTATTGCAGTAACTATAGTTGTTTTGA
CATCTATTCTTCGTCCGATGAGGCAGTTACACGAAACGATGGGTATTATTATCGATTCGCCAAGTGATTTGGAGCTTCGA
TCTAAGATTGGGAGTCATGATGAGATTGGTGCTTTGGCGCTTAACTTTAACTGTATGATGGATAAAATTCAAGAAAATAA
TCAGATGCAGATGCGTTTCTTGAGTGACGTCAGTCACGAATTACGTACTCCTATTGCAGTTATTAAGGGACATATGGACC
TCTTGCAACGTTGGGGTAAAAATGATCCTGAAATCCTTGAAGAAAGTCTTGAAGCTGCAAGTCACGAAGCCAACCGTATG
ACGATTATGATTAACGATATGTTGGATTCTATTCGTGTTAAAGGGTCATTTGACAATCATAGAAATGATACATGTGATTT
GAATTCTTCAATCCGTACGGTTATTGGGAATTTCCGTGTCCTACATGACGACTACCAATTCTACCTCAATGATTCTGAGA
GTTTAGATCGTCCAGCACAGATTTACAGCCAGCACTTTGAACAGGTTATTACTATTTTGATTGATAATGCGGTCAAGTAT
TCGCCTGTTAATAAGGAAATCCAGATTACTATCAAGGCTCTGGAAGATGAGATGCTGGTACAGGTACAGGATAATGGTGA
GGGTATCTCTAAAGAAGATATTGAACATATCTTTGAACGCTTCTATCGTTCAGATAAGGCGCGTAATCGTACGACAACCC
AATCTGGTGTGGGTATTGGTTTATCAATCCTCTATCAAATTGTGGAAGCTTATCGATGCCATATCGATGTCAGTTCAGAA
CTTGGTGTGGGTACACGTTTTGACCTCTACATTCCTTTTGCAGACTCAGAAACTACGACACCTCAACTTGAAGGTTAA

Domains

Predicted by InterproScan.

HAMP domain (HAMP)

(213-265)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(384-493)

His Kinase A (phospho-acceptor) domain (HisKA)

(270-329)

ArlS sensor domain (ArlS_N)

(39-187)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covS Streptococcus salivarius strain HSISS4

94.821

99.406

0.943

Multiple sequence alignment