Detailed information NTG1131100

Bioinformatically predicted

Overview

• Name: clpE
• Type: Regulator
• Locus tag: H0514_RS07035
• Genome accession: NZ_LR822020
• Coordinates: 1363041..1365299 (+)
• Length: 752 a.a.
• NCBI ID: WP_179972782.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus isolate STH_CIRM_956
• Function: repress competence development (at the early growth phase) (predicted from homology) Competence regulation

Genomic Context

Location: 1358041..1370299

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H0514_RS07010 (STHERMO_1612)	-	1359189..1359665 (-)	477	WP_179972786.1	ferrous iron transport protein A	-
H0514_RS07015 (STHERMO_1613)	-	1359839..1360573 (-)	735	WP_179972785.1	amino acid ABC transporter ATP-binding protein	-
H0514_RS07020 (STHERMO_1614)	-	1360573..1361253 (-)	681	WP_014608117.1	amino acid ABC transporter permease	-
H0514_RS07025 (STHERMO_1616)	-	1361521..1361751 (-)	231	WP_179972784.1	DUF1797 family protein	-
H0514_RS07030 (STHERMO_1617)	argF	1361820..1362800 (-)	981	WP_179972783.1	ornithine carbamoyltransferase	-
H0514_RS07035 (STHERMO_1618)	clpE	1363041..1365299 (+)	2259	WP_179972782.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
H0514_RS07040 (STHERMO_1619)	-	1365442..1365900 (+)	459	WP_179972781.1	NUDIX hydrolase	-
H0514_RS07045 (STHERMO_1620)	-	1365910..1366212 (+)	303	WP_179972780.1	DUF1827 family protein	-
H0514_RS07050 (STHERMO_1621)	-	1366208..1366378 (+)	171	Protein_1352	DUF1827 family protein	-
H0514_RS07055 (STHERMO_1622)	-	1366374..1366544 (+)	171	Protein_1353	DUF1827 family protein	-
H0514_RS07060	-	1366585..1367548 (-)	964	Protein_1354	Gfo/Idh/MocA family protein	-
H0514_RS07065 (STHERMO_1625)	-	1367647..1368882 (-)	1236	WP_179972778.1	aminoacyltransferase	-
H0514_RS07070 (STHERMO_1626)	-	1368860..1369351 (-)	492	WP_232086291.1	TVP38/TMEM64 family protein	-
H0514_RS07075 (STHERMO_1627)	-	1369615..1370235 (-)	621	WP_014621341.1	DUF3862 domain-containing protein	-

Sequence

Protein

• Length: 752 a.a.
• Molecular weight: 83854.10 Da
• Isoelectric Point: 5.1007

>NTDB_id=1131100 H0514_RS07035 WP_179972782.1 1363041..1365299(+) (clpE) [Streptococcus thermophilus isolate STH_CIRM_956]
MLCQNCNLNEASIHLYTNVNGNQQQVDLCQHCYKIMKSDPGNPLNQFNQAGGSNFFDDFFSDLNNFRSSNRDLPNTPPTQ
EGGNRGNGGPGRPGGPRQQAPQQLQGLLEEFGINITDIARRGDIDPVIGRDEEIIRVIEILNRRTKNNPVLIGEPGVGKT
AVVEGLAQKIVDGDVPQKLQSKQVIRLDVVSLVQGTGIRGQFEERMQKLMEEIRQRQDVILFIDEIHEIVGAGNTGDGNM
DAGNILKPALARGELQLVGATTLDEYRIIEKDAALERRMQPVKVDEPTVEETITILRGIQPKYQDYHHVKYTDEAITAAV
ELSNRYIQDRFLPDKAIDLLDESGSKMNLTLNFIDPKDLDKRLIEAENLKAQATRDEDFEKAAYFRDQIAKYKEMQQQTI
KDQDMPIITEKHIEAIVEQKTNIPVGDLKEKEQSQLLNLADDLKAHVIGQDAAVDKIAKAIRRNRVGLGAPNRPIGSFLF
VGPTGVGKTELSKQLAIELFGSSDSMIRFDMSEYMEKHAVAKLVGAPPGYVGYDEAGQLTEKVRRNPYSLILLDEIEKAH
PDVLHMFLQVLDDGRLTDGQGRTVSFKDTIIIMTSNAGTGKVEASVGFGAARENRTNSIINQLGDFFSPEFMNRFDGIIE
FNALSKENLLTIVDLMLDGVNQRLANNGIYLSVTDKVKEKLVDLGYDPKMGARPLRRTIQDHIEDAITDFYLKNPNEKDL
KAVMTSKGNITIKSAKKTEKTSQKTEALKEAN

Nucleotide

• Length: 2259 bp

>NTDB_id=1131100 H0514_RS07035 WP_179972782.1 1363041..1365299(+) (clpE) [Streptococcus thermophilus isolate STH_CIRM_956]
ATGCTCTGCCAAAACTGTAATCTTAATGAAGCTAGTATCCATTTGTATACCAACGTAAATGGTAATCAACAACAAGTTGA
CCTCTGTCAACATTGTTATAAAATCATGAAATCTGATCCAGGGAACCCCCTTAACCAATTCAATCAAGCAGGAGGTTCCA
ACTTCTTCGACGATTTCTTCAGTGACCTAAACAATTTCCGTTCTTCTAACAGAGACCTTCCTAATACACCTCCAACACAA
GAGGGAGGTAACCGTGGAAACGGTGGTCCGGGCCGTCCTGGAGGACCACGTCAACAAGCCCCTCAACAACTTCAAGGCCT
TCTCGAAGAATTCGGAATTAATATCACAGATATTGCTCGTCGTGGAGACATTGATCCTGTCATTGGTCGTGACGAAGAAA
TCATTCGCGTCATCGAAATTCTGAACCGCCGTACCAAGAACAATCCTGTTCTTATCGGTGAACCTGGTGTTGGTAAGACC
GCAGTAGTCGAAGGACTTGCCCAAAAAATTGTTGATGGAGATGTACCACAAAAACTCCAAAGCAAGCAAGTTATCCGTCT
TGATGTTGTAAGCCTAGTTCAAGGGACTGGTATCCGCGGCCAGTTCGAAGAACGCATGCAGAAGCTCATGGAGGAAATCC
GCCAACGTCAGGATGTTATCCTCTTTATTGATGAAATCCATGAAATTGTAGGAGCTGGTAATACTGGGGACGGCAATATG
GATGCTGGAAACATCTTAAAACCTGCACTTGCCCGTGGAGAGCTTCAACTTGTTGGAGCAACAACACTCGACGAATACCG
TATCATTGAGAAAGATGCGGCACTCGAACGTCGTATGCAACCCGTTAAGGTAGATGAGCCAACAGTTGAGGAAACAATCA
CAATTTTGCGTGGGATCCAGCCTAAATATCAAGACTACCACCATGTCAAATACACTGATGAAGCCATTACTGCAGCTGTA
GAATTATCCAACCGCTACATTCAGGACCGTTTCTTGCCAGACAAGGCCATCGACCTTCTCGATGAATCTGGCTCTAAGAT
GAATTTAACCCTCAACTTTATCGATCCTAAGGACCTCGATAAACGTTTAATTGAAGCTGAGAATCTTAAAGCTCAGGCTA
CTCGTGACGAAGACTTTGAAAAAGCTGCTTATTTCCGTGACCAAATTGCTAAATACAAGGAAATGCAACAGCAAACCATC
AAAGACCAAGATATGCCTATCATTACTGAGAAACATATCGAAGCCATTGTCGAGCAAAAAACCAATATTCCTGTCGGTGA
TTTAAAAGAAAAAGAACAATCTCAACTTCTCAACCTCGCCGATGACCTTAAGGCGCATGTTATTGGCCAAGATGCCGCAG
TTGATAAGATTGCTAAAGCTATCCGCCGTAATCGTGTTGGACTCGGTGCACCAAACCGCCCAATTGGTAGCTTCCTATTT
GTGGGTCCTACAGGAGTCGGTAAAACCGAGCTCTCTAAACAGTTAGCCATCGAGCTCTTTGGTTCATCTGATAGTATGAT
TCGTTTTGACATGTCAGAATACATGGAAAAACACGCTGTTGCTAAATTGGTCGGTGCTCCTCCAGGCTATGTTGGTTACG
ACGAAGCTGGGCAATTAACTGAAAAAGTCCGCCGTAACCCTTATTCACTCATTCTCCTTGATGAGATTGAAAAAGCTCAC
CCAGATGTTCTTCACATGTTCCTTCAGGTACTTGACGATGGTCGTCTGACTGATGGTCAAGGTAGAACTGTAAGTTTCAA
AGATACCATCATCATCATGACTTCAAATGCTGGTACTGGTAAAGTGGAAGCTAGTGTAGGTTTTGGAGCTGCTCGTGAGA
ATCGTACCAATTCTATTATCAACCAACTCGGAGATTTCTTCAGTCCTGAATTCATGAACCGTTTTGACGGTATTATCGAG
TTCAATGCCCTAAGCAAGGAAAATCTCCTTACTATCGTGGACCTTATGCTTGATGGCGTCAACCAACGCTTGGCAAACAA
CGGTATCTACCTCAGTGTAACTGATAAAGTTAAGGAAAAACTGGTTGACCTTGGTTATGATCCTAAGATGGGTGCTCGAC
CATTGCGTCGTACAATCCAAGACCACATTGAAGATGCTATTACAGACTTCTACCTTAAAAATCCAAATGAAAAAGATCTC
AAGGCTGTAATGACTTCAAAGGGGAACATCACCATTAAATCTGCTAAAAAAACTGAAAAAACTTCTCAGAAAACTGAAGC
ATTAAAAGAAGCCAACTAA

Domains

Predicted by InterproScan.

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (644-717)

• AAA domain (Cdc48 subfamily) (AAA_2) (473-636)

• ATPase family associated with various cellular activities (AAA) (AAA) (150-265)

• AAA lid domain (AAA_lid_9) (288-386)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpE	Streptococcus mutans UA159	83.888	99.867	0.838
clpE	Streptococcus pneumoniae Rx1	81.782	100	0.818
clpE	Streptococcus pneumoniae D39	81.782	100	0.818
clpE	Streptococcus pneumoniae R6	81.782	100	0.818
clpE	Streptococcus pneumoniae TIGR4	81.649	100	0.816
clpC	Lactococcus lactis subsp. cremoris KW2	75.726	100	0.763
clpC	Bacillus subtilis subsp. subtilis str. 168	52.234	86.303	0.451
clpC	Streptococcus pneumoniae Rx1	46.984	83.777	0.394
clpC	Streptococcus pneumoniae D39	46.984	83.777	0.394
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	47.2	83.112	0.392
clpC	Streptococcus pneumoniae TIGR4	46.825	83.777	0.392
clpC	Streptococcus thermophilus LMG 18311	46.89	83.378	0.391
clpC	Streptococcus thermophilus LMD-9	47.04	83.112	0.391
clpC	Streptococcus mutans UA159	46.645	83.245	0.388