Detailed information NTG1130985

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: H0511_RS07675
• Genome accession: NZ_LR822017
• Coordinates: 1508002..1509078 (-)
• Length: 358 a.a.
• NCBI ID: WP_179973962.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus isolate STH_CIRM_336
• Function: processing of CSP (predicted from homology) Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
IScluster/Tn	1506725..1507908	1508002..1509078	flank	94

Gene organization within MGE regions

Location: 1506725..1509078

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H0511_RS07675 (STHERMO_1724)	sepM	1508002..1509078 (-)	1077	WP_179973962.1	SepM family pheromone-processing serine protease	Regulator

Sequence

Protein

• Length: 358 a.a.
• Molecular weight: 39267.30 Da
• Isoelectric Point: 9.7882

>NTDB_id=1130985 H0511_RS07675 WP_179973962.1 1508002..1509078(-) (sepM) [Streptococcus thermophilus isolate STH_CIRM_336]
MANKTKSKSLLEKMWRIKWWLLSIFTLLFLLFALFFPLNNYYVELPGGAFDTKEVLTVNKKADDSKGSYNFVAVAQTKAT
LALMLYAKFNDFAKLQTAEEATGNYSDEDFIRINKFYMETSQNQAVYQGLTLAGKEVSLKYMGVYVLQVADDSSFKGVLN
IADTVTAVNGKTFDNSTDMIKYVQGLKLGSKVKVTYMRDGKEKTATGKIIKIANGKNGIGISLTDHTEIKSPENVKFKLD
GVGGPSAGLIFTLAIYDQVSGQDLKAGRKIAGTGTIEKDGTVGDIGGAYLKVKSAADSGADIFFVPNNLVTKEMKKVDPD
AKTNYQEAKEAAEKLGTKMKIVPVKTAQEAIDYLKKTK

Nucleotide

• Length: 1077 bp

>NTDB_id=1130985 H0511_RS07675 WP_179973962.1 1508002..1509078(-) (sepM) [Streptococcus thermophilus isolate STH_CIRM_336]
GTGGCAAACAAGACAAAATCTAAATCGCTACTAGAGAAAATGTGGCGTATTAAGTGGTGGTTATTAAGTATTTTTACGTT
ACTTTTCCTCCTTTTTGCCCTCTTTTTCCCTCTCAATAATTACTATGTGGAGCTTCCGGGTGGTGCTTTTGATACCAAGG
AAGTCTTGACAGTGAATAAGAAAGCTGATGATTCTAAGGGCTCCTATAATTTTGTGGCGGTGGCTCAAACCAAGGCGACT
TTGGCCTTGATGCTCTATGCTAAGTTTAATGATTTTGCAAAGCTTCAAACGGCTGAAGAGGCAACTGGAAATTACTCTGA
TGAAGATTTCATACGCATCAACAAATTTTACATGGAGACTTCTCAAAACCAAGCGGTTTATCAGGGCTTGACTCTGGCTG
GTAAGGAGGTTAGTTTGAAGTATATGGGTGTCTATGTGCTTCAGGTTGCTGATGATTCTAGCTTCAAGGGTGTCCTCAAT
ATCGCTGATACGGTGACGGCTGTTAATGGTAAGACCTTTGATAATTCGACTGACATGATTAAATACGTTCAAGGACTTAA
GCTGGGTTCAAAGGTCAAGGTCACTTATATGAGAGATGGTAAAGAAAAGACTGCTACTGGTAAGATTATTAAGATTGCCA
ATGGCAAAAATGGTATTGGTATCAGCCTAACGGACCATACTGAAATTAAGAGTCCTGAGAATGTTAAGTTTAAACTAGAT
GGTGTCGGTGGGCCAAGTGCTGGTCTTATATTTACCTTGGCTATTTACGATCAGGTGTCTGGTCAAGACCTCAAGGCTGG
CCGCAAGATTGCTGGTACAGGAACTATTGAAAAAGATGGGACTGTCGGTGATATCGGTGGGGCCTATCTCAAGGTGAAAT
CTGCGGCTGATAGTGGCGCAGACATTTTCTTCGTGCCAAATAATCTAGTAACTAAGGAAATGAAAAAGGTCGATCCGGAT
GCCAAGACTAATTATCAAGAGGCCAAGGAAGCTGCCGAGAAACTGGGCACCAAGATGAAAATCGTCCCTGTTAAAACAGC
TCAAGAAGCCATTGATTATTTGAAAAAGACTAAATGA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (140-206)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (244-321)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	62.17	95.251	0.592