Detailed information NTG1130944

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: H0511_RS00615
• Genome accession: NZ_LR822017
• Coordinates: 102388..104838 (+)
• Length: 816 a.a.
• NCBI ID: WP_179973245.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus isolate STH_CIRM_336
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 97388..109838

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H0511_RS00585 (STHERMO_0101)	-	97702..98653 (-)	952	Protein_80	S66 family peptidase	-
H0511_RS00595 (STHERMO_0103)	rpsB	99176..99943 (+)	768	WP_179974153.1	30S ribosomal protein S2	-
H0511_RS00600 (STHERMO_0104)	tsf	100054..101094 (+)	1041	WP_084830433.1	translation elongation factor Ts	-
H0511_RS00605 (STHERMO_0105)	-	101204..101674 (-)	471	WP_100285118.1	COG2426 family protein	-
H0511_RS00610 (STHERMO_0106)	-	101917..102387 (+)	471	WP_179974154.1	CtsR family transcriptional regulator	-
H0511_RS00615 (STHERMO_0107)	clpC	102388..104838 (+)	2451	WP_179973245.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
H0511_RS00620 (STHERMO_0108)	pbp3	104966..106222 (-)	1257	WP_179974155.1	D-alanyl-D-alanine carboxypeptidase PBP3	-
H0511_RS00625 (STHERMO_0109)	pbp3	106367..107614 (-)	1248	WP_179974156.1	D-alanyl-D-alanine carboxypeptidase PBP3	-

Sequence

Protein

• Length: 816 a.a.
• Molecular weight: 90442.61 Da
• Isoelectric Point: 5.6117

>NTDB_id=1130944 H0511_RS00615 WP_179973245.1 102388..104838(+) (clpC) [Streptococcus thermophilus isolate STH_CIRM_336]
MTIYSRKMQAIFHRAQLEAERFESPFLETWHVLLAMVEVPGSVAYLTFTDFEDRIHSEEIETAAVLAMEKRPKDLSESDI
IDLRAQSPALEAMLQEAQGIASVTGAVEVGSEHVLMAFLLHKDLMVCRLLEVAGFQYKDDSDKPRIIDLRRSLERNAGLS
KQDLKAIHDLRKPKKSKASGNFANMMQPPQSSTGELADYTKDLTALAESGNLDPVIGRDEEISRMIQVLSRKTKNNPVLV
GEAGVGKTALALGLAQRIASGEVPFELADMRILELDMMSVVAGTRFRGDFEERMNQIIDEIEADGKIILFIDELHTIIGS
GSGIDSTLDAANILKPALARGTLHMVGATTQAEYQKHIEKDAALSRRFAKITIEEPSVSEAIDILNGLRSSYEDYHRVTI
TDEAVETAVKAAHRYLTSKNLPDSAIDLLDEASATVQVRIKKEAKREITPLDEALLSGDIRAAVEQYKANQKAKFPKPAL
VDADQIMQTLSRLSGIPVEKMTQTDSKRYLNLESELHKRVIGQDEAVSVISRAIRRNQSGIRTGKRPIGSFMFLGPTGVG
KTELAKALAEVLFDDESALLRFDMSEYMEKFAASRLNGAPPGYVGYDEGGELTEKVRNKPYSVLLFDEIEKAHPDIFNVL
LQVLDDGVLTDSRGRKVDFSNTIIIMTSNLGATALRDDKTVGFGAQTISHNHQAMQARIMEELKKSYRPEFINRIDEKVV
FHSLEEEQLHDIVKIMVKPLISALADKGISLKFQPAALKHLAKDGYDIEMGARPLRRTIQTQVEDKLSELLLGGQVVSGQ
TLKIGCSKDKLTFTVV

Nucleotide

• Length: 2451 bp

>NTDB_id=1130944 H0511_RS00615 WP_179973245.1 102388..104838(+) (clpC) [Streptococcus thermophilus isolate STH_CIRM_336]
ATGACGATATATTCAAGAAAAATGCAGGCCATTTTCCATCGTGCTCAGCTTGAAGCGGAGCGTTTTGAAAGTCCTTTCTT
GGAGACTTGGCATGTGCTTCTGGCTATGGTTGAGGTTCCGGGATCTGTAGCCTACTTAACATTTACTGATTTTGAGGACC
GTATTCATTCAGAAGAGATTGAGACAGCTGCTGTATTGGCTATGGAGAAGAGGCCAAAAGACTTGTCGGAATCAGATATT
ATCGATTTACGTGCACAGTCACCTGCGCTAGAGGCTATGTTGCAAGAGGCGCAAGGAATCGCTAGTGTGACTGGTGCTGT
AGAGGTAGGGTCTGAACATGTATTGATGGCCTTCCTTCTTCATAAGGATTTAATGGTTTGTCGCCTCCTTGAAGTGGCTG
GTTTTCAATATAAAGATGATAGCGATAAACCTCGCATCATAGATTTACGACGTTCTTTGGAGCGTAATGCTGGTCTTAGC
AAGCAAGATTTGAAGGCAATTCACGATCTTCGTAAACCTAAGAAATCAAAAGCATCTGGGAATTTTGCCAATATGATGCA
ACCTCCTCAATCATCTACTGGTGAACTGGCAGATTATACCAAAGACTTAACTGCATTAGCGGAGTCAGGAAATCTTGATC
CCGTTATTGGACGCGATGAAGAAATTTCACGCATGATCCAGGTTTTGAGTCGTAAAACGAAGAATAATCCCGTCTTAGTA
GGTGAAGCTGGTGTCGGTAAGACAGCACTTGCTCTTGGTTTAGCGCAACGTATTGCTTCAGGCGAAGTACCATTTGAATT
GGCTGATATGCGTATCTTAGAGCTTGACATGATGAGCGTTGTTGCAGGGACACGTTTCCGTGGTGATTTCGAAGAGCGTA
TGAATCAGATTATTGATGAGATTGAAGCTGATGGGAAAATCATTCTCTTTATTGACGAACTACATACGATTATTGGATCT
GGTTCAGGTATTGATAGTACCTTGGACGCGGCTAATATTTTGAAACCGGCCCTTGCGCGCGGGACACTTCACATGGTTGG
AGCAACCACGCAAGCTGAATACCAAAAGCATATTGAGAAAGATGCGGCTTTATCCCGTCGTTTTGCTAAAATTACAATTG
AAGAACCAAGTGTATCTGAAGCAATCGATATTTTAAACGGTTTGCGTTCGTCTTATGAAGACTATCATCGTGTGACTATT
ACGGACGAGGCAGTTGAGACGGCAGTCAAGGCAGCGCATCGCTATTTGACGAGTAAGAATTTGCCTGATTCGGCAATTGA
TCTTTTAGATGAAGCGAGTGCAACTGTTCAAGTTCGTATCAAAAAAGAGGCCAAACGTGAGATAACACCTTTGGATGAAG
CACTTCTATCTGGGGATATTAGGGCTGCTGTTGAACAGTACAAGGCTAATCAAAAGGCAAAATTTCCTAAACCTGCTTTG
GTAGATGCGGATCAGATTATGCAAACTCTTAGTCGTTTATCAGGTATCCCTGTTGAGAAGATGACGCAGACTGACAGCAA
GCGTTACCTGAATCTTGAATCAGAACTCCACAAACGTGTTATTGGTCAAGATGAGGCAGTTTCGGTTATCAGCCGTGCTA
TTCGTCGTAATCAGTCAGGTATTCGTACTGGAAAACGTCCTATTGGCTCCTTCATGTTCCTTGGACCTACTGGTGTTGGT
AAGACAGAATTGGCCAAGGCTTTGGCGGAAGTTCTCTTTGATGATGAATCAGCTTTGCTTCGCTTTGATATGTCGGAATA
TATGGAAAAATTTGCGGCTAGTCGCCTTAATGGTGCTCCTCCAGGGTATGTCGGATATGATGAGGGTGGAGAGCTGACAG
AGAAAGTTCGAAATAAGCCCTACTCAGTTCTTCTCTTTGACGAGATTGAGAAAGCTCACCCAGATATCTTCAACGTTCTC
TTACAGGTTTTGGATGACGGTGTTTTAACAGATAGCCGTGGTCGTAAGGTTGATTTTTCAAACACTATCATCATTATGAC
CTCAAATTTGGGAGCTACAGCTCTTCGTGATGATAAAACTGTTGGTTTTGGTGCTCAAACTATTTCTCATAATCACCAAG
CCATGCAAGCACGCATTATGGAAGAGCTTAAGAAGTCCTATCGTCCAGAATTTATTAACCGTATTGATGAGAAGGTTGTC
TTCCACAGCTTAGAGGAAGAACAACTACATGACATTGTCAAGATTATGGTTAAACCATTAATTTCAGCTCTAGCCGATAA
AGGTATAAGCTTAAAATTCCAACCAGCTGCTCTTAAGCATTTGGCTAAGGATGGCTATGATATTGAGATGGGAGCTCGTC
CATTACGTCGTACGATTCAAACTCAAGTGGAGGACAAGTTGTCTGAGTTATTACTAGGTGGCCAAGTTGTTAGCGGACAG
ACCCTTAAGATTGGTTGCTCGAAAGATAAATTAACCTTTACAGTAGTGTAA

Domains

Predicted by InterproScan.

• ATPase family associated with various cellular activities (AAA) (AAA) (238-370)

• AAA domain (Cdc48 subfamily) (AAA_2) (546-717)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (724-804)

• AAA lid domain (AAA_lid_9) (377-456)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (107-135)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (15-46)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Streptococcus thermophilus LMG 18311	99.142	100	0.991
clpC	Streptococcus thermophilus LMD-9	98.775	100	0.988
clpC	Streptococcus mutans UA159	72.304	100	0.723
clpC	Streptococcus pneumoniae TIGR4	66.216	99.755	0.661
clpC	Streptococcus pneumoniae Rx1	66.216	99.755	0.661
clpC	Streptococcus pneumoniae D39	66.216	99.755	0.661
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	50.06	100	0.51
clpC	Bacillus subtilis subsp. subtilis str. 168	47.138	100	0.474
clpE	Streptococcus mutans UA159	47.604	76.716	0.365