Detailed information NTG0113083

Bioinformatically predicted

Overview

• Name: uvrA
• Type: Machinery gene
• Locus tag: HKU360_RS07770
• Genome accession: NZ_CP009612
• Coordinates: 1565759..1568587 (-)
• Length: 942 a.a.
• NCBI ID: WP_002988487.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain HKU360
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 1560759..1573587

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HKU360_RS07740 (HKU360_01594)	-	1561435..1562400 (+)	966	WP_002988504.1	LacI family DNA-binding transcriptional regulator	-
HKU360_RS07745 (HKU360_01595)	nusB	1562541..1562993 (-)	453	WP_038433825.1	transcription antitermination factor NusB	-
HKU360_RS07750 (HKU360_01596)	-	1562986..1563375 (-)	390	WP_002983163.1	Asp23/Gls24 family envelope stress response protein	-
HKU360_RS07755 (HKU360_01597)	efp	1563421..1563978 (-)	558	WP_002988496.1	elongation factor P	-
HKU360_RS07760 (HKU360_01598)	-	1564074..1564535 (-)	462	WP_002988493.1	deoxycytidylate deaminase	-
HKU360_RS07765 (HKU360_01599)	-	1564570..1565643 (-)	1074	WP_026031991.1	M24 family metallopeptidase	-
HKU360_RS07770 (HKU360_01600)	uvrA	1565759..1568587 (-)	2829	WP_002988487.1	excinuclease ABC subunit UvrA	Machinery gene
HKU360_RS07775 (HKU360_01601)	prx	1568814..1568996 (-)	183	WP_002988483.1	hypothetical protein	Regulator
HKU360_RS07780 (HKU360_01602)	mf2	1569236..1569994 (+)	759	WP_002985324.1	DNase Mf2	-
HKU360_RS07785 (HKU360_01603)	speC	1570105..1570812 (+)	708	WP_002988478.1	streptococcal pyrogenic exotoxin SpeC	-
HKU360_RS07790 (HKU360_01604)	-	1570880..1571014 (-)	135	WP_002988476.1	hypothetical protein	-
HKU360_RS07795 (HKU360_01605)	entC3	1571127..1571909 (-)	783	WP_002988472.1	enterotoxin type C3 EntC3	-
HKU360_RS07800 (HKU360_01606)	-	1572157..1573281 (-)	1125	WP_002988467.1	Fic family protein	-

Sequence

Protein

• Length: 942 a.a.
• Molecular weight: 104050.18 Da
• Isoelectric Point: 6.0690

>NTDB_id=113083 HKU360_RS07770 WP_002988487.1 1565759..1568587(-) (uvrA) [Streptococcus pyogenes strain HKU360]
MQNKIIIHGARAHNLKNIDVEIPRDKLVVVTGLSGSGKSSLAFDTIYAEGQRRYVESLSAYARQFLGNMEKPDVDSIDGL
SPAISIDQKTTSKNPRSTVGTVTEINDYLRLLYARVGTPYCINGHGAITASSAEQIVEQVLALPERTRMQILAPIVRRKK
GQHKTIFEKIQKDGYVRVRVDGDIFDVTEVPELSKSKMHNIEVVIDRLVNKDGIRSRLFDSVEAALRLGDGYLMIDTMDG
NELLFSEHYSCPVCGFTVPELEPRLFSFNAPFGSCPTCDGLGIKLEVDLDLVVPDPSKSLREGALAPWNPISSNYYPTML
EQAMASFGVDMDTPFEALTEEERDLVLYGSGDREFHFHYVNDFGGERNIDIPFEGVVTNVNRRYHETNSDYTRNVMRGYM
NELTCATCHGYRLNDQALCVHVGGEEGPHIGQISELSIADHLQLLEELELTENESTIAKPIVKEIHDRLTFLNNVGLNYL
TLSRAAGTLSGGESQRIRLATQIGSNLSGVIYILDEPSIGLHQRDNDRLIESLKKMRDLGNTLIVVEHDEDTMMQADWLI
DVGPGAGEFGGEIIASGTPKQVAKNKKSITGQYLSGKKFIPVPLERRSGNGRFIEIKGAAQNNLQSLDVRFPLGKFIAVT
GVSGSGKSTLVNSILKKAVAQKLNRNADKPGKYHSISGIEHIERLIDIDQSPIGRTPRSNPATYTGVFDDIRDLFAQTNE
AKIRGYKKGRFSFNVKGGRCEACSGDGIIKIEMHFLPDVYVPCEVCHGRRYNSETLEVHYKEKNIAEVLDMTVDDALVFF
SAIPKTARKIQTIKDVGLGYVTLGQPATTLSGGEAQRMKLASELHKRSTGKSLYILDEPTTGLHTDDIARLLKVLERFVD
DGNTVLVIEHNLDVIKSADHIIDLGPEGGVGGGQIVATGTPEEVAQVKESYTGHYLKVKLQQ

Nucleotide

• Length: 2829 bp

>NTDB_id=113083 HKU360_RS07770 WP_002988487.1 1565759..1568587(-) (uvrA) [Streptococcus pyogenes strain HKU360]
ATGCAAAATAAAATAATAATTCATGGGGCAAGAGCCCACAATTTAAAAAATATTGACGTGGAAATTCCACGAGACAAATT
AGTTGTCGTGACAGGGTTATCAGGGTCAGGAAAATCTAGTCTAGCCTTTGATACTATTTATGCGGAAGGGCAACGTCGTT
ACGTAGAAAGTTTATCAGCTTATGCTAGACAGTTCTTGGGTAATATGGAAAAACCAGATGTGGATTCCATTGACGGTCTT
AGCCCTGCTATTTCCATTGATCAAAAAACTACCAGTAAGAACCCCCGCTCAACGGTTGGTACGGTTACGGAAATCAATGA
TTATTTACGTTTACTATATGCGCGTGTGGGCACACCTTACTGTATTAATGGGCATGGGGCCATTACAGCATCTTCTGCAG
AACAAATTGTAGAGCAGGTCTTAGCCCTCCCTGAACGGACACGCATGCAGATTTTAGCGCCTATTGTTCGCCGGAAAAAA
GGTCAACACAAAACCATTTTTGAGAAAATTCAAAAAGATGGTTATGTCCGTGTGCGGGTTGACGGGGATATTTTTGACGT
GACAGAAGTGCCGGAGCTGTCCAAAAGTAAGATGCACAACATCGAGGTGGTTATTGACCGTCTGGTTAATAAGGATGGTA
TTCGTAGCCGTTTATTTGATTCGGTTGAAGCAGCTTTAAGGCTGGGAGATGGCTACCTTATGATTGACACTATGGATGGC
AATGAACTGCTCTTTTCTGAGCATTATTCCTGTCCTGTCTGTGGGTTTACGGTTCCTGAATTAGAACCAAGACTCTTCTC
TTTTAATGCGCCGTTCGGCTCTTGTCCGACCTGTGATGGGCTAGGCATTAAGTTGGAAGTGGATTTGGACTTGGTTGTTC
CTGACCCAAGTAAGTCTTTGAGAGAGGGAGCTTTGGCGCCTTGGAATCCTATTTCCTCCAATTATTACCCAACCATGCTT
GAGCAAGCTATGGCAAGTTTTGGGGTGGATATGGATACACCTTTTGAGGCCTTGACTGAGGAAGAAAGAGATTTAGTGCT
TTATGGTTCAGGAGATAGAGAATTTCATTTTCACTATGTGAATGATTTTGGTGGTGAGCGTAACATTGATATTCCTTTTG
AAGGTGTTGTGACTAATGTTAATCGTCGTTATCACGAAACTAATAGTGATTATACGCGCAATGTGATGCGTGGTTATATG
AACGAATTGACCTGTGCGACTTGTCATGGTTACCGTTTGAATGACCAAGCCTTGTGTGTGCATGTGGGTGGCGAAGAAGG
ACCTCATATTGGTCAAATTTCAGAATTATCGATTGCCGACCACTTGCAGTTGTTGGAAGAATTGGAACTCACAGAAAATG
AAAGTACCATTGCTAAACCGATTGTCAAAGAAATTCATGACCGCCTGACCTTCTTAAATAATGTGGGACTGAATTATCTG
ACCTTGTCACGGGCTGCTGGGACTTTATCAGGTGGTGAAAGTCAACGAATCAGGTTAGCGACACAAATTGGTTCTAACTT
ATCAGGGGTGATCTATATCTTGGATGAGCCTTCTATTGGATTGCACCAAAGAGACAATGACCGTTTGATCGAAAGCCTGA
AAAAAATGCGTGATTTGGGTAATACCTTAATTGTGGTAGAACACGATGAAGACACCATGATGCAGGCAGACTGGCTGATT
GATGTGGGGCCTGGGGCAGGTGAGTTCGGTGGAGAAATTATTGCCTCTGGAACGCCGAAACAAGTGGCTAAGAATAAAAA
ATCCATCACGGGTCAATATTTGTCTGGTAAAAAATTCATTCCAGTGCCATTAGAGCGTCGTTCTGGTAATGGGCGATTCA
TTGAAATAAAAGGAGCAGCGCAGAATAATCTTCAAAGCCTCGACGTGAGATTCCCACTGGGTAAATTTATTGCGGTCACA
GGGGTATCAGGCTCAGGGAAATCAACCTTGGTTAATAGTATTTTGAAAAAGGCTGTCGCCCAAAAATTAAACCGTAATGC
TGATAAGCCTGGTAAATATCACTCTATTTCTGGTATTGAACATATTGAACGCTTGATTGACATTGACCAAAGTCCGATTG
GAAGGACGCCACGGTCAAATCCAGCCACCTATACGGGTGTCTTTGATGATATTCGAGACTTGTTTGCCCAAACCAACGAA
GCTAAGATTCGTGGCTACAAAAAAGGCCGTTTCTCTTTTAATGTCAAAGGTGGGCGTTGTGAGGCTTGTTCAGGTGATGG
GATTATCAAAATCGAAATGCACTTTTTGCCAGATGTTTATGTGCCTTGTGAGGTTTGCCACGGCAGACGGTATAATTCTG
AGACGCTTGAGGTGCATTATAAAGAAAAAAATATTGCTGAAGTACTTGACATGACTGTCGATGATGCCTTGGTATTTTTC
TCTGCTATCCCTAAAACTGCCCGAAAAATTCAAACCATTAAGGATGTTGGTTTGGGTTATGTGACCTTGGGTCAACCAGC
TACTACTCTATCTGGAGGAGAAGCGCAGCGGATGAAATTAGCTAGTGAATTGCACAAACGCTCGACAGGTAAGAGCTTGT
ATATCCTAGATGAGCCAACGACTGGTTTACACACAGATGATATTGCAAGGCTATTAAAAGTTTTGGAACGCTTTGTAGAC
GATGGTAATACGGTTCTTGTGATTGAGCATAATTTGGACGTTATCAAATCTGCTGACCATATTATTGACTTAGGACCAGA
AGGTGGTGTCGGAGGTGGTCAGATTGTTGCCACGGGGACACCAGAAGAGGTAGCTCAAGTTAAAGAAAGCTATACTGGTC
ATTATTTGAAAGTAAAACTACAACAATAG

Domains

Predicted by InterProScan.

• UvrA DNA-binding domain (UvrA_DNA-bind) (288-396)

• ABC transporter (ABC_tran) (624-860)

• UvrA interaction domain (UvrA_inter) (132-238)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
uvrA	Streptococcus pneumoniae R6	84.713	100	0.847
uvrA	Streptococcus pneumoniae TIGR4	84.713	100	0.847
uvrA	Streptococcus pneumoniae D39	84.713	100	0.847