Detailed information    

insolico Bioinformatically predicted

Overview

Name   radA   Type   Machinery gene
Locus tag   GPW69_RS09775 Genome accession   NZ_LR738724
Coordinates   2022893..2024260 (-) Length   455 a.a.
NCBI ID   WP_024404944.1    Uniprot ID   A0A4T2GZR1
Organism   Streptococcus suis isolate 9401240     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Genomic island 2013327..2025250 2022893..2024260 within 0


Gene organization within MGE regions


Location: 2013327..2025250
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GPW69_RS09725 - 2013327..2013827 (+) 501 WP_044772045.1 NUDIX hydrolase -
  GPW69_RS09730 mmuM 2013877..2014824 (-) 948 WP_044772044.1 homocysteine S-methyltransferase -
  GPW69_RS09735 - 2014837..2016213 (-) 1377 WP_044772043.1 amino acid permease -
  GPW69_RS09740 tnpA 2016449..2016943 (-) 495 Protein_1871 IS200/IS605 family transposase -
  GPW69_RS09745 gltX 2017124..2018578 (-) 1455 WP_044772042.1 glutamate--tRNA ligase -
  GPW69_RS09750 - 2018650..2019930 (-) 1281 WP_044772041.1 MFS transporter -
  GPW69_RS09755 - 2020021..2020680 (-) 660 WP_074391215.1 LiaF transmembrane domain-containing protein -
  GPW69_RS09760 - 2020685..2021131 (-) 447 WP_074391216.1 LytTR family DNA-binding domain-containing protein -
  GPW69_RS09765 - 2021309..2022067 (-) 759 WP_013730631.1 TIGR00266 family protein -
  GPW69_RS09770 - 2022275..2022769 (-) 495 WP_074391217.1 beta-class carbonic anhydrase -
  GPW69_RS09775 radA 2022893..2024260 (-) 1368 WP_024404944.1 DNA repair protein RadA Machinery gene
  GPW69_RS09780 - 2024267..2024800 (-) 534 WP_074391218.1 histidine phosphatase family protein -
  GPW69_RS09785 - 2024807..2025250 (-) 444 WP_002939955.1 dUTP diphosphatase -

Sequence

Protein


Download         Length: 455 a.a.        Molecular weight: 49871.38 Da        Isoelectric Point: 6.1911

>NTDB_id=1129619 GPW69_RS09775 WP_024404944.1 2022893..2024260(-) (radA) [Streptococcus suis isolate 9401240]
MIIAKKKTTFVCQSCEYHSPKYLGRCPNCGSWSSFVEEVEVAEVKNERVSLTGEKTRPMKLNEVSSIQVARTKTNMEEFN
RVLGGGVVPGSLVLIGGDPGIGKSTLLLQVSTQLSTIGTVLYVSGEESAQQIKLRAERLGDIDSEFYLYAETNMQSIRTE
IEKIKPDFLIIDSIQTIMSPDISSVQGSVSQVREVTNELMQIAKTNNIATFIVGHMTKEGTLAGPRTLEHMVDTVLYFEG
ERQHTFRILRAVKNRFGSTNEIGIFEMQSQGLVEVLNPSEVFLEERLDGATGSAIVVTMEGTRPILAEVQALVTPTMFGN
AKRTTTGLDFNRASLIMAVLEKRAGLLLQNQDAYLKSAGGVKLDEPAIDLAVAVALASSYKDKPTNPQECFIGEIGLTGE
IRRVNRIEQRINEAAKLGFTKVYAPKNSLTGIKVPKEITVIGVTTIGEVLQKVFN

Nucleotide


Download         Length: 1368 bp        

>NTDB_id=1129619 GPW69_RS09775 WP_024404944.1 2022893..2024260(-) (radA) [Streptococcus suis isolate 9401240]
ATCATCATCGCTAAGAAAAAAACAACCTTTGTCTGTCAATCCTGCGAGTACCACTCGCCCAAGTATCTGGGCCGTTGTCC
AAACTGTGGCTCCTGGTCTAGCTTTGTCGAGGAAGTGGAAGTTGCAGAAGTCAAGAACGAGCGGGTCAGCCTGACAGGTG
AGAAGACCCGTCCCATGAAACTCAATGAAGTTTCCTCCATTCAAGTGGCCCGCACCAAGACCAACATGGAAGAGTTCAAC
CGCGTCCTCGGTGGCGGTGTGGTACCAGGAAGTCTGGTCTTGATCGGAGGCGATCCAGGGATTGGCAAATCCACCCTGCT
CTTGCAGGTTTCTACCCAGCTTTCGACCATTGGCACGGTCCTCTATGTGTCGGGGGAAGAGTCTGCCCAGCAGATTAAGT
TGCGGGCGGAGCGTTTGGGCGACATCGACAGCGAGTTCTATCTCTATGCGGAGACCAATATGCAGAGCATTCGGACCGAG
ATTGAGAAGATAAAACCAGATTTCCTGATTATCGACTCTATCCAGACCATTATGAGCCCTGACATCTCCAGCGTGCAAGG
CTCTGTCAGTCAGGTCCGTGAAGTAACCAATGAACTCATGCAGATTGCCAAGACCAACAACATCGCAACCTTCATCGTCG
GCCACATGACCAAGGAAGGCACCTTGGCTGGACCGCGGACCCTGGAGCACATGGTGGACACCGTTCTCTATTTTGAGGGC
GAGCGACAGCACACCTTCCGTATCTTGCGGGCGGTCAAAAACCGCTTTGGCTCCACCAACGAAATCGGCATTTTTGAAAT
GCAGTCACAGGGCTTGGTCGAAGTCCTCAATCCTAGTGAAGTCTTTCTAGAAGAGCGTCTGGACGGGGCGACAGGCTCTG
CTATTGTCGTGACCATGGAGGGCACCCGCCCTATCCTTGCAGAAGTGCAGGCCCTGGTGACGCCGACCATGTTTGGCAAT
GCCAAGCGGACCACGACAGGCTTGGACTTCAACCGTGCCAGCTTGATTATGGCGGTTTTGGAAAAACGGGCAGGCCTGCT
CCTCCAAAACCAAGATGCCTACCTCAAGTCGGCAGGCGGTGTCAAACTGGATGAGCCAGCTATTGACCTAGCGGTCGCAG
TTGCCCTTGCCTCCAGTTATAAGGATAAGCCGACCAACCCACAAGAGTGCTTTATAGGCGAAATCGGTCTGACAGGTGAA
ATCCGCCGCGTCAATCGGATTGAACAACGGATTAACGAAGCCGCTAAATTGGGCTTTACCAAGGTCTATGCCCCCAAAAA
TTCTCTGACCGGTATCAAGGTGCCCAAGGAAATCACCGTTATCGGCGTGACCACCATTGGCGAAGTCTTGCAGAAAGTGT
TCAACTGA

Domains

Predicted by InterproScan.

Rubredoxin metal binding domain (Zn_ribbon_LapB)

(10-37)

AAA domain (AAA_25)

(64-220)

Subunit ChlI of Mg-chelatase (ChlI)

(363-427)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A4T2GZR1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  radA Streptococcus mitis NCTC 12261

91.372

99.341

0.908
  radA Streptococcus pneumoniae Rx1

91.15

99.341

0.905
  radA Streptococcus pneumoniae D39

91.15

99.341

0.905
  radA Streptococcus pneumoniae R6

91.15

99.341

0.905
  radA Streptococcus pneumoniae TIGR4

91.15

99.341

0.905
  radA Streptococcus mitis SK321

90.929

99.341

0.903
  radA Bacillus subtilis subsp. subtilis str. 168

62.693

99.56

0.624

Multiple sequence alignment