Detailed information NTG0112955

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: NF38_RS00650
• Genome accession: NZ_CP009610
• Coordinates: 139724..142294 (-)
• Length: 856 a.a.
• NCBI ID: WP_011272249.1
• Uniprot ID: -
• Organism: Haemophilus influenzae strain Hi375
• Function: degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 134724..147294

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NF38_RS00625 (NF38_00625)	pdxH	134818..135450 (-)	633	WP_038440325.1	pyridoxamine 5'-phosphate oxidase	-
NF38_RS00630 (NF38_00630)	-	135643..136350 (+)	708	WP_038440326.1	7-cyano-7-deazaguanine/7-aminomethyl-7- deazaguanine transporter	-
NF38_RS00640 (NF38_00640)	rnr	136542..138890 (+)	2349	WP_038440328.1	ribonuclease R	-
NF38_RS00645 (NF38_00645)	rlmB	138946..139686 (+)	741	WP_011272250.1	23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB	-
NF38_RS00650 (NF38_00650)	clpC	139724..142294 (-)	2571	WP_011272249.1	ATP-dependent chaperone ClpB	Regulator
NF38_RS00655 (NF38_00655)	-	142422..142985 (-)	564	WP_011272248.1	5-formyltetrahydrofolate cyclo-ligase	-
NF38_RS00660 (NF38_00660)	-	143308..143610 (-)	303	WP_005651366.1	cell division protein ZapA	-
NF38_RS00665 (NF38_00665)	polA	143759..146551 (+)	2793	WP_038440330.1	DNA polymerase I	-
NF38_RS00670 (NF38_00670)	-	146566..146808 (+)	243	Protein_130	serine dehydratase subunit alpha family protein	-

Sequence

Protein

• Length: 856 a.a.
• Molecular weight: 95674.09 Da
• Isoelectric Point: 5.0182

>NTDB_id=112955 NF38_RS00650 WP_011272249.1 139724..142294(-) (clpC) [Haemophilus influenzae strain Hi375]
MNIEKFTTKFQEALSEAQSLAIGKDNQFIEPVHLLTALLNQQGGSIAPILTASGVNVALLRNELKTELNKLPQVIGNGGD
VQLSRQLINLLNLCDKFAQQNQDKFISSELFLLAALEERGTISDILKKCGAKKEQISQAIQHIRGGQNVNDQNAEESRQA
LEKYTIDLTARAESGKLDPVIGRDEEIRRAIQVLQRRTKNNPVLIGEPGVGKTAIVEGLAQRIVNGEVPEGLKNKRVLSL
DMGALIAGAKYRGEFEERLKAVLNELSKEEGRVILFIDEIHTMVGAGKTDGAMDAGNLLKPSLARGELHCVGATTLDEYR
QYIEKDAALERRFQKVFVDEPSVEDTIAILRGLKERYEIHHHVDITDPAIVAAATLSHRYISDRQLPDKAIDLIDEAASS
IRMEIDSKPEPLDRLERRIIQLKLEQQALQKEEDEASRKRLEMLEKELAEKEREYAELEEVWKSEKATLSGSQHIKQELD
TAKTELEQARRAGDLAKMSELQYGRIPALEKQLEQAETSEGKEMTLLRYRVTDEEIAEVLSKATGIPVSKMMEGEKEKLL
RMEDELHKRVIGQEEAVDAVANAIRRSRAGLSDPNRPIGSFLFLGPTGVGKTELCKTLAKFLFDSEDAMVRIDMSEFMEK
HSVSRLVGAPPGYVGYEEGGYLTEAVRRRPYSVILLDEVEKAHADVFNILLQVLDDGRLTDGQGRTVDFRNTVVIMTSNL
GSDLIQGNKDESYSEMKALVMSVVSQHFRPEFINRIDETVVFHPLGKENIRAIASIQLERLAKRMETRGYELVFTDALLD
FIGEVGYDPIYGARPLKRAIQQEIENSLAQQILSGALLPGKVVTIDYANAEVQARQ

Nucleotide

• Length: 2571 bp

>NTDB_id=112955 NF38_RS00650 WP_011272249.1 139724..142294(-) (clpC) [Haemophilus influenzae strain Hi375]
ATGAACATTGAAAAATTTACGACAAAATTCCAAGAAGCGTTAAGCGAAGCACAATCACTTGCTATCGGAAAAGACAATCA
ATTTATTGAACCCGTGCATTTATTGACCGCACTTTTAAATCAACAGGGCGGCTCTATTGCGCCAATTTTGACAGCAAGTG
GCGTAAATGTGGCTTTATTGCGTAATGAATTAAAGACAGAACTAAATAAATTGCCGCAAGTGATTGGCAATGGTGGAGAT
GTACAACTTTCACGCCAGCTTATTAATTTACTTAATCTATGCGATAAATTCGCACAGCAAAACCAAGATAAATTTATTTC
GAGCGAATTGTTTTTGCTTGCAGCTTTAGAAGAACGAGGAACGATCAGCGATATTTTGAAAAAGTGCGGTGCGAAAAAAG
AACAAATTTCGCAAGCTATTCAGCACATTAGAGGGGGACAAAACGTGAACGATCAAAATGCAGAAGAAAGCAGACAAGCT
CTTGAAAAATATACGATTGATTTAACCGCTCGTGCAGAAAGTGGCAAACTTGATCCTGTAATTGGGCGTGATGAAGAAAT
TCGTCGAGCCATTCAAGTATTACAACGTCGTACCAAAAATAACCCTGTGTTAATTGGTGAACCAGGTGTAGGGAAAACGG
CGATTGTCGAAGGCTTGGCACAGCGTATCGTAAACGGCGAAGTGCCAGAAGGTTTGAAAAATAAACGTGTGCTTTCATTA
GATATGGGCGCATTGATTGCTGGTGCAAAATATCGCGGAGAATTTGAAGAACGTTTAAAAGCGGTGCTCAATGAACTTTC
TAAAGAAGAAGGTCGCGTGATCCTCTTTATTGATGAAATTCATACTATGGTCGGCGCGGGTAAAACCGATGGTGCGATGG
ATGCGGGTAACTTATTAAAACCAAGTTTAGCGCGCGGTGAATTACATTGCGTGGGTGCAACAACGTTAGACGAATATCGT
CAATATATCGAAAAAGATGCCGCACTTGAGCGCCGTTTCCAAAAAGTATTTGTGGACGAACCAAGTGTAGAAGACACCAT
TGCTATCTTACGTGGTTTGAAAGAACGCTATGAAATTCATCATCACGTGGATATTACTGACCCTGCGATTGTCGCTGCCG
CAACGCTTTCACATCGTTATATTTCCGATCGTCAATTGCCGGATAAAGCCATTGATTTGATCGATGAAGCGGCGTCTAGC
ATTCGTATGGAAATAGATTCTAAACCTGAACCGCTTGATCGCCTTGAACGTCGAATTATCCAATTAAAATTGGAACAACA
GGCATTACAAAAAGAAGAAGACGAAGCAAGTCGCAAACGTTTAGAAATGTTAGAGAAAGAATTGGCTGAAAAAGAACGTG
AATACGCCGAACTTGAAGAAGTATGGAAATCTGAAAAAGCAACGCTTTCTGGCTCTCAACATATTAAACAAGAATTAGAT
ACTGCAAAAACCGAACTAGAACAAGCTCGTCGCGCGGGTGATTTAGCGAAAATGTCAGAGTTGCAATATGGACGCATCCC
TGCTCTTGAAAAGCAACTCGAGCAAGCTGAAACCAGCGAAGGAAAAGAAATGACGCTTTTACGCTATCGTGTCACGGATG
AAGAAATCGCAGAAGTGCTTTCTAAAGCCACAGGTATTCCTGTATCCAAAATGATGGAAGGCGAGAAAGAAAAACTCTTG
CGCATGGAAGATGAACTACATAAACGAGTGATTGGTCAAGAAGAAGCAGTTGATGCGGTAGCAAACGCGATTCGTCGTAG
TCGTGCTGGTCTTTCCGATCCTAATCGCCCAATTGGTTCATTCTTGTTCCTAGGGCCAACAGGTGTGGGTAAAACAGAGC
TTTGCAAAACTTTGGCTAAATTCTTGTTTGATAGTGAAGATGCGATGGTGCGCATTGATATGTCAGAGTTTATGGAAAAG
CACAGTGTCTCTCGTTTAGTGGGTGCGCCTCCAGGCTATGTCGGCTATGAAGAAGGCGGTTATTTAACTGAGGCTGTTCG
TCGTCGTCCATATTCAGTGATCTTATTAGATGAAGTTGAAAAAGCCCATGCGGATGTATTCAATATCTTATTACAAGTAT
TGGATGATGGTCGTTTAACTGACGGGCAAGGTCGTACTGTGGACTTCCGTAATACGGTGGTAATTATGACCTCTAACTTG
GGTTCTGATTTAATCCAAGGTAACAAAGACGAAAGCTATAGCGAAATGAAAGCCTTAGTGATGTCAGTGGTAAGCCAACA
TTTCCGTCCCGAATTCATCAACCGTATTGACGAAACTGTGGTATTCCATCCGCTTGGTAAAGAGAATATTCGTGCGATTG
CAAGTATCCAATTAGAACGCTTAGCAAAACGTATGGAAACTCGTGGCTATGAATTAGTGTTTACCGACGCTTTATTAGAT
TTCATTGGTGAAGTGGGGTATGACCCAATTTATGGTGCACGTCCATTGAAACGTGCTATTCAACAAGAGATCGAAAACAG
CTTGGCACAACAAATTCTATCTGGTGCGTTATTACCTGGTAAGGTTGTTACCATTGATTACGCCAACGCAGAAGTTCAAG
CTAGACAATAG

Domains

Predicted by InterProScan.

• Clp amino terminal domain, pathogenicity island component (Clp_N) (94-145)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (17-68)

• ATPase family associated with various cellular activities (AAA) (AAA) (203-336)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (765-845)

• AAA domain (Cdc48 subfamily) (AAA_2) (596-758)

• AAA lid domain (AAA_lid_9) (342-443)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Bacillus subtilis subsp. subtilis str. 168	47.181	100	0.479
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	43.572	100	0.447
clpE	Streptococcus pneumoniae TIGR4	49.12	79.673	0.391
clpE	Streptococcus pneumoniae R6	48.311	79.556	0.384
clpE	Streptococcus pneumoniae Rx1	48.311	79.556	0.384
clpE	Streptococcus pneumoniae D39	48.311	79.556	0.384
clpE	Streptococcus mutans UA159	47.724	79.556	0.38
clpC	Lactococcus lactis subsp. cremoris KW2	45.467	82.477	0.375