Detailed information NTG1129486

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: STREPSUIS_RS02180
• Genome accession: NZ_LR738722
• Coordinates: 411223..412272 (+)
• Length: 349 a.a.
• NCBI ID: WP_012775295.1
• Uniprot ID: A0A2K1T047
• Organism: Streptococcus suis isolate 861160
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 406223..417272

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
STREPSUIS_RS02145	-	406525..407463 (+)	939	WP_232049074.1	sensor histidine kinase	-
STREPSUIS_RS02150	-	407616..408218 (+)	603	WP_024405571.1	response regulator transcription factor	-
STREPSUIS_RS02155	-	408526..408744 (+)	219	WP_024405570.1	YqgQ family protein	-
STREPSUIS_RS02160	-	408744..409130 (+)	387	WP_004194735.1	rhodanese-like domain-containing protein	-
STREPSUIS_RS02165	-	409187..409909 (+)	723	WP_024405569.1	hypothetical protein	-
STREPSUIS_RS02170	rsmD	410219..410758 (+)	540	WP_014638485.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
STREPSUIS_RS02175	coaD	410748..411236 (+)	489	WP_002939048.1	pantetheine-phosphate adenylyltransferase	-
STREPSUIS_RS02180	sepM	411223..412272 (+)	1050	WP_012775295.1	SepM family pheromone-processing serine protease	Regulator
STREPSUIS_RS02185	-	412460..413101 (+)	642	WP_024382386.1	YutD family protein	-
STREPSUIS_RS02190	rlmN	413110..414222 (+)	1113	WP_012028433.1	23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN	-
STREPSUIS_RS02195	-	414219..414746 (+)	528	WP_012027591.1	VanZ family protein	-
STREPSUIS_RS02205	nadE	416042..416866 (-)	825	WP_004194617.1	ammonia-dependent NAD(+) synthetase	-

Sequence

Protein

• Length: 349 a.a.
• Molecular weight: 37761.83 Da
• Isoelectric Point: 4.6112

>NTDB_id=1129486 STREPSUIS_RS02180 WP_012775295.1 411223..412272(+) (sepM) [Streptococcus suis isolate 861160]
MKKNRKLTLIASIVLGTLLIWFAVFVRLPYYLESPGGAADIRQVLTVNNQIDQEDGSYNFTYVSVQQATALQLFAAQFDP
YTTVRSSEEMTGGADNEEYFRIARFYMETSQNMAKYQGLTLAGKEVNLDFFGVYVLALTDDSTFKKVLNIADTVVSINGK
TFESSPDLIKYVSGLEVGSDVTVGYISAGQEKSADGKIIKLSNGKNGIGITLVDHTEVQSSIPIDFQTGDIGGPSAGLMF
TLAIYTQLAEPDLRDGRIIAGTGTIEQDGKVGDIGGADKKVISAAKSGASIFFVPNNPVDVEVLKKNPKAKTNYEEAKEA
AEKAGLDIEVVPVKTVQEAIDYLKKTKGE

Nucleotide

• Length: 1050 bp

>NTDB_id=1129486 STREPSUIS_RS02180 WP_012775295.1 411223..412272(+) (sepM) [Streptococcus suis isolate 861160]
ATGAAGAAAAATAGGAAGTTAACCTTAATTGCATCTATTGTTTTAGGAACTCTTTTGATTTGGTTTGCCGTTTTTGTTCG
TCTGCCTTATTATCTGGAAAGTCCAGGTGGAGCTGCCGATATTCGTCAGGTACTAACGGTGAACAATCAAATAGACCAAG
AGGATGGCTCTTACAACTTCACCTATGTATCAGTCCAACAGGCTACAGCTTTACAACTATTCGCTGCTCAGTTTGATCCC
TATACGACAGTTCGTTCCTCTGAAGAGATGACAGGAGGGGCCGACAATGAGGAGTATTTCCGTATAGCACGGTTTTACAT
GGAGACATCGCAAAATATGGCGAAGTACCAAGGTTTGACCTTGGCAGGAAAAGAAGTCAATCTTGATTTCTTTGGTGTCT
ATGTGCTTGCCTTGACGGATGATTCAACCTTTAAAAAAGTTCTTAATATTGCCGACACTGTTGTGAGTATCAATGGAAAA
ACATTTGAGTCTTCTCCTGATTTGATTAAATATGTGAGTGGCTTGGAGGTTGGAAGTGATGTAACAGTTGGTTATATTAG
CGCTGGTCAGGAAAAATCTGCGGACGGTAAGATTATCAAATTGTCTAATGGCAAAAACGGGATAGGTATCACTCTCGTAG
ATCATACAGAGGTTCAAAGTTCGATTCCGATTGATTTCCAAACAGGAGATATTGGTGGTCCAAGTGCTGGTCTGATGTTT
ACACTTGCCATCTATACTCAACTCGCAGAGCCTGACTTACGTGATGGTCGGATTATTGCTGGTACGGGGACTATCGAGCA
GGATGGAAAAGTAGGTGACATTGGTGGGGCTGATAAGAAGGTCATTTCGGCAGCTAAGTCTGGTGCAAGTATCTTTTTTG
TACCAAACAATCCAGTTGATGTAGAAGTTTTGAAGAAAAATCCAAAGGCTAAAACGAACTATGAAGAAGCTAAGGAAGCA
GCCGAGAAAGCAGGTCTAGATATTGAGGTAGTTCCTGTGAAAACTGTTCAAGAGGCTATTGATTATTTGAAGAAAACAAA
GGGCGAGTAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (132-195)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (232-315)

3D structure

• AlphaFold DB: A0A2K1T047

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	60.807	99.427	0.605