Detailed information NTG1129455

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: GPW51_RS07820
• Genome accession: NZ_LR738721
• Coordinates: 1542338..1543387 (-)
• Length: 349 a.a.
• NCBI ID: WP_012775295.1
• Uniprot ID: A0A2K1T047
• Organism: Streptococcus suis isolate S10
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1537338..1548387

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GPW51_RS07795	nadE	1537744..1538568 (+)	825	WP_004194617.1	ammonia-dependent NAD(+) synthetase	-
GPW51_RS07805	-	1539864..1540391 (-)	528	WP_012027591.1	VanZ family protein	-
GPW51_RS07810	rlmN	1540388..1541500 (-)	1113	WP_074413233.1	23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN	-
GPW51_RS07815	-	1541509..1542150 (-)	642	WP_012027595.1	YutD family protein	-
GPW51_RS07820	sepM	1542338..1543387 (-)	1050	WP_012775295.1	SepM family pheromone-processing serine protease	Regulator
GPW51_RS07825	coaD	1543374..1543862 (-)	489	WP_012027597.1	pantetheine-phosphate adenylyltransferase	-
GPW51_RS07830	rsmD	1543852..1544391 (-)	540	WP_009910569.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
GPW51_RS07835	-	1544699..1545421 (-)	723	WP_012027598.1	lipoprotein	-
GPW51_RS07840	-	1545478..1545864 (-)	387	WP_004194735.1	rhodanese-like domain-containing protein	-
GPW51_RS07845	-	1545864..1546082 (-)	219	WP_004194736.1	YqgQ family protein	-
GPW51_RS07850	-	1546390..1546992 (-)	603	WP_012027601.1	response regulator transcription factor	-
GPW51_RS07855	-	1546989..1548083 (-)	1095	WP_012027602.1	sensor histidine kinase	-

Sequence

Protein

• Length: 349 a.a.
• Molecular weight: 37761.83 Da
• Isoelectric Point: 4.6112

>NTDB_id=1129455 GPW51_RS07820 WP_012775295.1 1542338..1543387(-) (sepM) [Streptococcus suis isolate S10]
MKKNRKLTLIASIVLGTLLIWFAVFVRLPYYLESPGGAADIRQVLTVNNQIDQEDGSYNFTYVSVQQATALQLFAAQFDP
YTTVRSSEEMTGGADNEEYFRIARFYMETSQNMAKYQGLTLAGKEVNLDFFGVYVLALTDDSTFKKVLNIADTVVSINGK
TFESSPDLIKYVSGLEVGSDVTVGYISAGQEKSADGKIIKLSNGKNGIGITLVDHTEVQSSIPIDFQTGDIGGPSAGLMF
TLAIYTQLAEPDLRDGRIIAGTGTIEQDGKVGDIGGADKKVISAAKSGASIFFVPNNPVDVEVLKKNPKAKTNYEEAKEA
AEKAGLDIEVVPVKTVQEAIDYLKKTKGE

Nucleotide

• Length: 1050 bp

>NTDB_id=1129455 GPW51_RS07820 WP_012775295.1 1542338..1543387(-) (sepM) [Streptococcus suis isolate S10]
ATGAAGAAAAATAGGAAGTTAACCTTAATTGCATCTATTGTTTTAGGAACTCTTTTGATTTGGTTTGCCGTTTTTGTTCG
TCTGCCTTATTATCTGGAAAGTCCAGGTGGAGCTGCCGATATTCGTCAGGTACTAACGGTGAACAATCAAATAGACCAAG
AGGATGGCTCTTACAACTTCACCTATGTATCAGTCCAACAGGCTACAGCTTTACAACTATTCGCTGCTCAGTTTGATCCC
TATACGACAGTTCGTTCCTCTGAAGAGATGACAGGAGGGGCCGACAATGAGGAGTATTTCCGTATAGCACGGTTTTACAT
GGAGACATCGCAAAATATGGCGAAGTACCAAGGTTTGACCTTGGCAGGAAAAGAAGTCAATCTTGATTTCTTTGGTGTCT
ATGTGCTTGCCTTGACGGATGATTCAACCTTTAAAAAAGTTCTTAATATTGCCGACACTGTTGTGAGTATCAATGGAAAA
ACATTTGAGTCTTCTCCTGATTTGATTAAATATGTGAGTGGCTTGGAGGTTGGAAGTGATGTAACAGTTGGTTATATTAG
CGCTGGTCAGGAAAAATCTGCGGACGGTAAGATTATCAAATTGTCTAATGGCAAAAACGGGATAGGTATCACTCTCGTAG
ATCATACAGAGGTTCAAAGTTCGATTCCGATTGATTTCCAAACAGGAGATATTGGTGGTCCAAGTGCTGGTCTGATGTTT
ACACTTGCCATCTATACTCAACTCGCAGAGCCTGACTTACGTGATGGTCGGATTATTGCTGGTACGGGGACTATCGAGCA
GGATGGAAAAGTAGGTGACATTGGTGGGGCTGATAAGAAGGTCATTTCGGCAGCTAAGTCTGGTGCAAGTATCTTTTTTG
TACCAAACAATCCAGTTGATGTAGAAGTTTTGAAGAAAAATCCAAAGGCTAAAACGAACTATGAAGAAGCTAAGGAAGCA
GCCGAGAAAGCAGGTCTAGATATTGAGGTAGTTCCTGTGAAAACTGTTCAAGAGGCTATTGATTATTTGAAGAAAACAAA
GGGCGAGTAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (132-195)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (232-315)

3D structure

• AlphaFold DB: A0A2K1T047

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	60.807	99.427	0.605