Detailed information NTG0112849

Bioinformatically predicted

Overview

• Name: degS
• Type: Regulator
• Locus tag: M036_RS18190
• Genome accession: NZ_CP005997
• Coordinates: 3489884..3491041 (-)
• Length: 385 a.a.
• NCBI ID: WP_003227983.1
• Uniprot ID: A0A199WDV9
• Organism: Bacillus subtilis TO-A
• Function: phosphorylation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 3484884..3496041

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
M036_RS18160 (M036_18125)	yvyF	3485137..3485556 (-)	420	WP_003227995.1	TIGR03826 family flagellar region protein	-
M036_RS18165 (M036_18130)	comFC	3485630..3486352 (-)	723	WP_003227991.1	comF operon protein ComFC	Machinery gene
M036_RS18170 (M036_18135)	comFB	3486316..3486612 (-)	297	WP_003227989.1	late competence protein ComFB	-
M036_RS18175 (M036_18140)	comFA	3486672..3488063 (-)	1392	WP_003243962.1	ATP-dependent helicase ComFA	Machinery gene
M036_RS18180 (M036_18145)	fakBA	3488169..3489014 (-)	846	WP_003244125.1	DegV family protein	-
M036_RS18185 (M036_18150)	degU	3489112..3489801 (-)	690	WP_003219701.1	two-component system response regulator DegU	Regulator
M036_RS18190 (M036_18155)	degS	3489884..3491041 (-)	1158	WP_003227983.1	two-component sensor histidine kinase DegS	Regulator
M036_RS18195 (M036_18160)	yvyE	3491258..3491911 (+)	654	WP_003227979.1	YigZ family protein	-
M036_RS18200 (M036_18165)	tagV	3491911..3493086 (+)	1176	WP_003244117.1	polyisoprenyl-teichoic acid--peptidoglycan teichoic acid transferase TagV	-
M036_RS18205 (M036_18170)	tagO	3493159..3494235 (-)	1077	WP_003227975.1	MraY family glycosyltransferase	-
M036_RS18210 (M036_18175)	tuaH	3494380..3495573 (-)	1194	WP_003243252.1	glycosyltransferase family 1 protein	-

Sequence

Protein

• Length: 385 a.a.
• Molecular weight: 44957.76 Da
• Isoelectric Point: 6.2957

>NTDB_id=112849 M036_RS18190 WP_003227983.1 3489884..3491041(-) (degS) [Bacillus subtilis TO-A]
MNKTKMDSKVLDSILMKMLKTVDGSKDEVFQIGEQSRQQYEQLVEELKQIKQQVYEVIELGDKLEVQTRHARNRLSEVSR
NFHRFSEEEIRNAYEKAHKLQVELTMIQQREKQLRERRDDLERRLLGLQEIIERSESLVSQITVVLNYLNQDLREVGLLL
ADAQAKQDFGLRIIEAQEEERKRVSREIHDGPAQMLANVMMRSELIERIFRDRGAEDGFQEIKNLRQNVRNALYEVRRII
YDLRPMALDDLGLIPTLRKYLYTTEEYNGKVKIHFQCIGETEDQRLAPQFEVALFRLAQEAVSNALKHSESEEITVKVEI
TKDFVILMIKDNGKGFDLKEAKEKKNKSFGLLGMKERVDLLEGTMTIDSKIGLGTFIMIKVPLSL

Nucleotide

• Length: 1158 bp

>NTDB_id=112849 M036_RS18190 WP_003227983.1 3489884..3491041(-) (degS) [Bacillus subtilis TO-A]
ATGAATAAAACAAAGATGGATTCCAAAGTGCTGGATTCTATTTTGATGAAGATGCTGAAAACCGTTGACGGGAGCAAGGA
CGAGGTTTTTCAAATCGGGGAGCAGTCACGCCAGCAGTATGAACAGCTGGTCGAAGAACTGAAACAAATTAAACAGCAGG
TGTATGAAGTGATTGAGCTTGGCGATAAACTTGAAGTGCAAACTCGCCATGCGAGAAACCGTTTATCCGAGGTCAGCCGT
AATTTTCATAGATTCAGTGAAGAGGAAATCCGCAATGCTTATGAAAAAGCCCATAAGCTGCAGGTAGAATTGACGATGAT
CCAGCAGCGTGAGAAGCAATTGCGCGAACGGCGGGACGATTTGGAGCGCAGATTGCTAGGGCTTCAGGAAATCATTGAGC
GGTCAGAATCATTAGTAAGCCAAATTACAGTTGTGCTCAACTACTTGAATCAGGATTTGCGCGAAGTTGGACTGCTTCTT
GCTGATGCTCAGGCAAAACAGGATTTCGGCTTAAGAATTATTGAGGCGCAGGAAGAAGAGCGAAAAAGAGTCTCAAGAGA
AATCCATGACGGACCCGCTCAAATGCTGGCGAATGTTATGATGAGATCGGAATTAATCGAGCGGATTTTCCGTGACCGGG
GCGCAGAGGACGGATTCCAAGAAATTAAAAATCTCCGCCAAAATGTTCGGAATGCCCTTTACGAAGTGAGAAGGATTATA
TATGATTTAAGACCGATGGCCCTTGATGACCTAGGCCTGATTCCAACTTTAAGAAAATATCTATATACAACCGAGGAATA
TAACGGGAAGGTCAAAATACATTTTCAGTGCATTGGAGAAACAGAGGATCAGAGGCTAGCGCCTCAGTTTGAGGTTGCGC
TCTTCAGGCTCGCACAGGAAGCTGTGTCTAATGCGCTAAAGCATTCTGAATCTGAAGAAATTACAGTCAAAGTTGAGATC
ACAAAGGATTTTGTGATTTTAATGATAAAAGATAACGGTAAAGGGTTCGACCTGAAGGAAGCGAAAGAGAAGAAAAACAA
ATCATTCGGCTTGCTGGGCATGAAAGAAAGAGTAGATTTATTGGAAGGAACGATGACAATAGATTCGAAAATAGGTCTTG
GGACATTTATTATGATTAAGGTTCCGTTATCTCTTTGA

Domains

Predicted by InterproScan.

• Histidine kinase (HisKA_3) (180-248)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (291-384)

• Sensor protein DegS (DegS) (12-170)

3D structure

• AlphaFold DB: A0A199WDV9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
degS	Bacillus subtilis subsp. subtilis str. 168	100	100	1