Detailed information NTG1128474

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: FQT45_RS02600
• Genome accession: NZ_LR595858
• Coordinates: 496830..497873 (+)
• Length: 347 a.a.
• NCBI ID: WP_077323511.1
• Uniprot ID: A0A4U9XHT5
• Organism: Streptococcus pseudoporcinus strain NCTC10228
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 491830..502873

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FQT45_RS02575 (NCTC10228_00520)	arcC	491905..492855 (+)	951	WP_007892664.1	carbamate kinase	-
FQT45_RS02580 (NCTC10228_00521)	-	492961..494487 (-)	1527	WP_077353901.1	IS1182 family transposase	-
FQT45_RS02585 (NCTC10228_00522)	asnA	494729..495721 (+)	993	WP_007894038.1	aspartate--ammonia ligase	-
FQT45_RS02590 (NCTC10228_00523)	rsmD	495823..496362 (+)	540	WP_077323509.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
FQT45_RS02595 (NCTC10228_00524)	coaD	496352..496843 (+)	492	WP_077323510.1	pantetheine-phosphate adenylyltransferase	-
FQT45_RS02600 (NCTC10228_00525)	sepM	496830..497873 (+)	1044	WP_077323511.1	SepM family pheromone-processing serine protease	Regulator
FQT45_RS02605 (NCTC10228_00526)	-	498100..499083 (+)	984	WP_077323512.1	LacI family DNA-binding transcriptional regulator	-
FQT45_RS02610 (NCTC10228_00527)	-	499076..499987 (+)	912	WP_077323513.1	ribokinase	-
FQT45_RS02615 (NCTC10228_00528)	rbsD	499962..500360 (+)	399	WP_077323514.1	D-ribose pyranase	-
FQT45_RS02620 (NCTC10228_00529)	-	500376..501854 (+)	1479	WP_077323515.1	sugar ABC transporter ATP-binding protein	-
FQT45_RS02625 (NCTC10228_00530)	-	501857..502801 (+)	945	WP_077323516.1	ABC transporter permease subunit	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 38365.34 Da
• Isoelectric Point: 10.1350

>NTDB_id=1128474 FQT45_RS02600 WP_077323511.1 496830..497873(+) (sepM) [Streptococcus pseudoporcinus strain NCTC10228]
MKIIKKVKWWLISILAVVALLFALFFPLPYYIEMPGGAYDIRSVLKVNDKRDKEKGSYNFVAVSLSRATFAQILYAWVTP
FTEISSLENTTGGYSATDYMRINQYYMETSQNGAIYQALQLAGKPVSLDYLGVYVLDVNKESTFRGILNIADTVTGVNQK
EFKSSTELIKYVSSLKRGETVTVQYTSGNEKKSKSGKVIKLKNGKNGIGIGLTDHTKVHTDEKIEFSTEGVGGPSAGLMF
TLDIYDQLNQENLRKGRRIAGTGTIDQDGKVGDIGGAGLKVVAAANEGADIFFVPNNPVDKRIKKVKPNAKTNYKEALEV
AKKIKTKMKIVPVRNVKEAIAYLQKTK

Nucleotide

• Length: 1044 bp

>NTDB_id=1128474 FQT45_RS02600 WP_077323511.1 496830..497873(+) (sepM) [Streptococcus pseudoporcinus strain NCTC10228]
ATGAAGATAATTAAAAAAGTTAAATGGTGGTTAATTAGTATTCTGGCAGTAGTTGCCCTCTTGTTTGCCCTCTTTTTCCC
TTTACCTTATTATATTGAGATGCCTGGTGGAGCTTACGATATTCGTTCAGTACTTAAGGTAAACGATAAAAGGGATAAGG
AGAAAGGCTCTTATAATTTTGTGGCGGTCAGTTTGAGTCGAGCCACTTTTGCTCAAATTCTCTATGCTTGGGTAACGCCA
TTCACAGAGATTTCATCTTTGGAAAATACAACTGGTGGCTATAGTGCGACAGATTATATGCGCATCAATCAATATTACAT
GGAGACCTCTCAAAACGGAGCTATCTATCAAGCCTTACAATTAGCTGGGAAACCTGTTTCTTTAGACTACCTAGGTGTTT
ATGTTTTGGATGTCAATAAAGAGTCTACTTTTCGTGGTATTCTAAATATTGCTGATACTGTTACAGGAGTCAATCAAAAA
GAATTTAAGAGTTCAACTGAACTTATTAAATACGTTTCAAGTTTGAAACGGGGTGAAACAGTGACGGTGCAATATACCAG
CGGTAATGAGAAAAAATCTAAAAGTGGCAAGGTTATTAAGCTAAAAAATGGGAAGAATGGTATTGGAATTGGCTTAACGG
ACCACACAAAAGTCCATACAGATGAAAAGATTGAGTTTTCGACAGAAGGTGTAGGTGGGCCAAGTGCTGGGCTTATGTTT
ACACTGGATATTTATGATCAACTAAATCAAGAAAACCTGCGTAAAGGTCGTCGTATTGCTGGTACTGGAACGATTGATCA
AGATGGCAAAGTTGGTGATATTGGTGGTGCGGGATTAAAAGTTGTTGCTGCAGCTAACGAAGGGGCTGATATTTTCTTTG
TACCCAACAATCCAGTTGATAAACGGATCAAAAAAGTAAAACCAAATGCAAAGACCAATTATAAAGAAGCCTTGGAAGTC
GCTAAAAAAATAAAAACCAAGATGAAAATTGTTCCCGTTAGAAATGTTAAAGAAGCTATTGCTTACTTGCAAAAGACAAA
ATAA

Domains

Predicted by InterproScan.

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (232-340)

• PDZ domain (PDZ_2) (131-192)

3D structure

• AlphaFold DB: A0A4U9XHT5

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	71.884	99.424	0.715