Detailed information NTG1128426

Bioinformatically predicted

Overview

• Name: clpE
• Type: Regulator
• Locus tag: FQT67_RS03420
• Genome accession: NZ_LR595857
• Coordinates: 641399..643690 (-)
• Length: 763 a.a.
• NCBI ID: WP_080148002.1
• Uniprot ID: A0A9X9R244
• Organism: Streptococcus sp. NCTC 11567 strain NCTC11567
• Function: repress competence development (at the early growth phase) (predicted from homology) Competence regulation

Genomic Context

Location: 636399..648690

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FQT67_RS03405 (NCTC11567_00707)	ileS	637270..640071 (+)	2802	WP_046176951.1	isoleucine--tRNA ligase	-
FQT67_RS03410 (NCTC11567_00709)	-	640474..640776 (-)	303	WP_046176950.1	DUF1827 family protein	-
FQT67_RS03415 (NCTC11567_00710)	-	640826..641281 (-)	456	WP_046176949.1	NUDIX hydrolase	-
FQT67_RS03420 (NCTC11567_00711)	clpE	641399..643690 (-)	2292	WP_080148002.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
FQT67_RS03425 (NCTC11567_00712)	-	643988..644218 (+)	231	WP_003051836.1	DUF1797 family protein	-
FQT67_RS03430 (NCTC11567_00713)	-	644346..645032 (+)	687	WP_003051835.1	amino acid ABC transporter permease	-
FQT67_RS03435 (NCTC11567_00714)	-	645032..645766 (+)	735	WP_003061973.1	amino acid ABC transporter ATP-binding protein	-
FQT67_RS03440 (NCTC11567_00715)	-	645965..646444 (+)	480	WP_003056958.1	ferrous iron transport protein A	-
FQT67_RS03445 (NCTC11567_00716)	feoB	646441..648600 (+)	2160	WP_003056946.1	ferrous iron transport protein B	-

Sequence

Protein

• Length: 763 a.a.
• Molecular weight: 85027.33 Da
• Isoelectric Point: 5.2784

>NTDB_id=1128426 FQT67_RS03420 WP_080148002.1 641399..643690(-) (clpE) [Streptococcus sp. NCTC 11567 strain NCTC11567]
MLCQNCNLNESTIHLYTNVNGKQKQVDLCQNCYQIMKTDPTNPILGGLNGGQRAQERSSNPFFDDFFGDLNNFRAFGNLP
NTPPTQAGQNGNGGGRHGGHFNGQRPTQPQTPNQQAKGLLEEFGINVTDIARHGDIDPVIGRDDEITRVIEILNRRTKNN
PVLIGEPGVGKTAVVEGLAQKIVDGTVPHKLQGKQVIRLDVVSLVQGTGIRGQFEERMQKLMEEIRQRKDVILFIDEIHE
IVGAGSAGDGNMDAGNILKPALARGELQLVGATTLNEYRIIEKDAALERRMQPVKVDEPSVEETITILKGIQPKYEDYHH
VKYSPAAIEAAAHLSNRYIQDRFLPDKAIDLLDEAGSKMNLTLNFVDPKEIDKRLIEAENLKAQATRDEDYERAAYFRDQ
IAKFKEMQAQKVDEQDIPIITEKTIEAIIEQKTNIPVGDLKEKEQSQLVNLANDLKAHVIGQDDAVDKIAKAIRRNRVGL
GTPNRPIGSFLFVGPTGVGKTELSKQLAIELFGSADNMIRFDMSEYMEKHAVAKLVGAPPGYVGYEEAGQLTEQVRRNPY
SLILLDEVEKAHPDVMHMFLQVLDDGRLTDGQGRTVSFKDTIIIMTSNAGTGKSEASVGFGAAREGRTSSVLGELSNFFS
PEFMNRFDGIIEFKALSKDNLLHIVDLMLEDVNKRLSYNEIHLDVTQKVKEKLVDLGYDPKMGARPLRRTIQDYIEDAIT
DYYLEHPTEKDLRAIMTSNSNIMIKAAKKDETVTAKQDKTDEN

Nucleotide

• Length: 2292 bp

>NTDB_id=1128426 FQT67_RS03420 WP_080148002.1 641399..643690(-) (clpE) [Streptococcus sp. NCTC 11567 strain NCTC11567]
ATGCTTTGTCAAAATTGTAATTTAAACGAATCAACCATTCACCTCTACACGAATGTTAATGGAAAACAAAAACAAGTTGA
CCTTTGTCAAAACTGTTATCAAATCATGAAGACTGACCCTACTAATCCTATTTTAGGTGGCCTAAATGGAGGTCAAAGAG
CCCAAGAACGCTCATCCAACCCCTTCTTTGATGACTTTTTTGGGGACTTAAATAATTTTAGAGCCTTTGGCAACCTTCCA
AATACCCCACCTACTCAGGCAGGGCAAAATGGAAATGGTGGGGGACGCCATGGTGGTCATTTCAATGGACAACGTCCCAC
TCAGCCACAAACACCAAATCAGCAAGCAAAAGGCTTACTAGAAGAATTTGGCATTAATGTGACCGATATTGCAAGACATG
GTGATATTGACCCTGTCATCGGTCGAGATGACGAGATTACACGTGTCATCGAAATCCTTAACCGTCGGACTAAAAATAAC
CCTGTGCTTATTGGGGAACCAGGAGTTGGTAAAACAGCTGTTGTAGAAGGTCTAGCCCAAAAAATTGTAGATGGCACAGT
ACCTCACAAATTGCAAGGTAAGCAAGTGATCCGTCTAGATGTGGTTAGTCTTGTTCAAGGCACAGGTATCCGTGGTCAAT
TCGAAGAACGCATGCAAAAATTAATGGAAGAAATTCGTCAACGCAAAGATGTGATTCTCTTTATTGATGAAATTCATGAA
ATTGTAGGTGCTGGTTCTGCTGGAGATGGCAATATGGATGCTGGCAATATTTTAAAACCAGCCTTGGCCCGTGGTGAGTT
GCAACTCGTTGGTGCTACTACCTTAAATGAATACCGTATTATTGAAAAAGATGCTGCCTTGGAGCGGCGGATGCAGCCGG
TGAAAGTTGACGAACCTTCTGTAGAAGAAACCATTACCATCTTAAAAGGTATCCAACCCAAATATGAAGACTATCATCAT
GTCAAATATAGCCCAGCAGCTATCGAGGCTGCTGCACACTTATCCAATCGCTACATCCAAGACCGATTCCTCCCTGATAA
GGCCATTGACCTTCTGGATGAAGCTGGTTCAAAAATGAATTTAACTCTTAATTTTGTTGACCCTAAAGAGATTGACAAAC
GTCTGATTGAAGCAGAAAACCTCAAAGCTCAAGCAACTCGTGACGAAGATTACGAACGAGCAGCCTATTTCCGTGATCAA
ATTGCGAAATTCAAGGAAATGCAAGCTCAAAAAGTCGACGAACAGGATATTCCTATCATTACTGAAAAAACCATTGAAGC
CATCATTGAACAAAAAACCAATATTCCAGTTGGCGACTTGAAAGAAAAAGAACAATCTCAACTCGTTAATTTGGCTAATG
ATTTGAAAGCTCACGTGATTGGCCAAGATGATGCCGTTGACAAAATTGCCAAGGCCATTCGCCGGAACCGTGTGGGATTG
GGAACTCCAAATCGTCCTATTGGTTCTTTCCTATTCGTTGGGCCAACAGGTGTTGGTAAAACAGAGTTGTCTAAGCAACT
AGCTATTGAACTCTTTGGCTCTGCTGACAATATGATTCGCTTTGATATGTCCGAATACATGGAAAAACATGCCGTTGCTA
AATTAGTCGGGGCTCCTCCTGGTTATGTGGGCTATGAAGAAGCTGGCCAGTTAACGGAACAAGTTCGCCGCAACCCATAT
TCACTTATTCTCTTAGATGAGGTGGAAAAGGCTCATCCTGACGTCATGCACATGTTTTTACAAGTTCTTGATGATGGCCG
TTTAACAGATGGTCAAGGACGGACAGTCAGCTTCAAGGATACTATTATTATCATGACCTCTAATGCTGGAACAGGTAAAA
GCGAAGCTTCTGTTGGATTTGGTGCAGCTAGAGAAGGACGAACAAGCTCTGTCCTTGGTGAATTAAGTAACTTCTTCAGC
CCAGAGTTCATGAACCGTTTCGATGGTATTATTGAATTTAAGGCCTTGAGCAAAGATAACCTCTTGCATATCGTTGATTT
AATGCTGGAAGATGTTAATAAGCGCTTAAGCTATAATGAGATTCACCTTGATGTGACACAAAAAGTCAAAGAAAAATTAG
TAGATTTAGGCTATGATCCTAAAATGGGTGCTCGACCACTCCGTCGTACCATCCAAGATTATATCGAAGATGCGATTACG
GACTACTATTTGGAACACCCCACTGAAAAGGACTTGCGTGCCATAATGACAAGTAACAGTAATATCATGATTAAAGCTGC
CAAAAAAGATGAAACGGTAACAGCTAAACAAGATAAGACCGACGAGAACTAA

Domains

Predicted by InterproScan.

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (656-730)

• AAA domain (Cdc48 subfamily) (AAA_2) (485-648)

• AAA lid domain (AAA_lid_9) (300-397)

• ATPase family associated with various cellular activities (AAA) (AAA) (162-281)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpE	Streptococcus mutans UA159	85.45	99.083	0.847
clpE	Streptococcus pneumoniae Rx1	83.926	99.476	0.835
clpE	Streptococcus pneumoniae D39	83.926	99.476	0.835
clpE	Streptococcus pneumoniae R6	83.926	99.476	0.835
clpE	Streptococcus pneumoniae TIGR4	83.926	99.476	0.835
clpC	Lactococcus lactis subsp. cremoris KW2	76.495	96.461	0.738
clpC	Bacillus subtilis subsp. subtilis str. 168	51.138	86.37	0.442
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	46.615	85.19	0.397
clpC	Streptococcus pneumoniae Rx1	47.84	81.913	0.392
clpC	Streptococcus pneumoniae D39	47.84	81.913	0.392
clpC	Streptococcus pneumoniae TIGR4	47.84	81.913	0.392
clpC	Streptococcus mutans UA159	47.411	80.996	0.384
clpC	Streptococcus thermophilus LMD-9	46.795	81.782	0.383
clpC	Streptococcus thermophilus LMG 18311	46.474	81.782	0.38