Detailed information    

insolico Bioinformatically predicted

Overview

Name   endA   Type   Machinery gene
Locus tag   FJH52_RS09330 Genome accession   NZ_LR595848
Coordinates   1859381..1860205 (-) Length   274 a.a.
NCBI ID   WP_001036789.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 4559 isolate 4559     
Function   cleavage of dsDNA into ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 1854381..1865205
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FJH52_RS09325 - 1857759..1859090 (-) 1332 WP_000390043.1 hemolysin family protein -
  FJH52_RS09330 endA 1859381..1860205 (-) 825 WP_001036789.1 DNA-entry nuclease EndA Machinery gene
  FJH52_RS09335 - 1860244..1860432 (-) 189 WP_001813390.1 DNA-directed RNA polymerase subunit beta -
  FJH52_RS09340 murA 1860425..1861708 (-) 1284 WP_000358028.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
  FJH52_RS09345 - 1861732..1861962 (-) 231 WP_000250392.1 DUF1146 family protein -
  FJH52_RS09350 sepM 1862020..1863057 (-) 1038 WP_000727278.1 SepM family pheromone-processing serine protease Regulator
  FJH52_RS09355 coaD 1863041..1863529 (-) 489 WP_001280769.1 pantetheine-phosphate adenylyltransferase -
  FJH52_RS09360 rsmD 1863519..1864058 (-) 540 WP_000706963.1 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD -
  FJH52_RS09365 asnA 1864123..1865115 (-) 993 WP_000747993.1 aspartate--ammonia ligase -

Sequence

Protein


Download         Length: 274 a.a.        Molecular weight: 29966.67 Da        Isoelectric Point: 10.1700

>NTDB_id=1128350 FJH52_RS09330 WP_001036789.1 1859381..1860205(-) (endA) [Streptococcus pneumoniae strain 4559 isolate 4559]
MNKKTRQTLIGLLVLLLLSTGSYYIKQMQSTANSPKTKLNQKKQASEAPSQALAESVLTDAVKSQIKGSLEWNGSGAFIV
NGNKTNLDAKVSSKPYADNKTKTVGKETVPTVANALLSKATRQYKNRKETGNGSTSWTPPGWHQVKNLKGSYTHAVDRGH
LLGYALIGGLDGFDASTSNPKNIAVQTAWANQAQAEYSTGQNYYESKVRKALDQNKRVRYRVTLYYASNEDLVPSASQIE
AKSSDGELEFNVLVPNVQKGLQLDYRTGEVTVTQ

Nucleotide


Download         Length: 825 bp        

>NTDB_id=1128350 FJH52_RS09330 WP_001036789.1 1859381..1860205(-) (endA) [Streptococcus pneumoniae strain 4559 isolate 4559]
ATGAACAAAAAAACAAGACAGACACTAATCGGACTGCTAGTGTTATTGCTTTTGTCTACAGGGAGCTATTATATCAAGCA
GATGCAGTCGACAGCTAATAGTCCTAAAACCAAGCTTAATCAGAAAAAACAAGCGTCTGAAGCTCCTAGTCAAGCATTGG
CAGAGAGTGTCTTAACAGACGCAGTCAAGAGTCAAATAAAGGGGAGTCTGGAGTGGAATGGCTCAGGTGCTTTTATCGTC
AATGGTAATAAAACAAATCTAGATGCCAAGGTTTCAAGTAAGCCCTACGCTGACAATAAAACAAAGACAGTGGGCAAGGA
AACTGTTCCAACCGTAGCTAATGCCCTCTTGTCTAAGGCCACTCGTCAGTACAAGAATCGTAAAGAAACTGGGAATGGTT
CAACTTCTTGGACTCCTCCAGGTTGGCATCAGGTCAAGAATCTAAAGGGCTCTTATACCCATGCAGTCGATAGAGGTCAT
TTGTTAGGCTATGCCTTAATCGGTGGTTTGGATGGTTTTGATGCCTCAACAAGCAATCCTAAAAACATTGCTGTTCAGAC
AGCCTGGGCAAATCAGGCACAAGCCGAGTATTCGACTGGTCAAAACTACTATGAAAGCAAGGTGCGTAAAGCCTTGGACC
AAAACAAGCGTGTCCGTTACCGTGTAACCCTTTACTACGCTTCAAACGAGGATTTAGTTCCCTCAGCTTCACAGATTGAA
GCCAAGTCTTCGGATGGAGAATTGGAATTCAATGTTCTAGTTCCCAATGTTCAAAAGGGACTTCAACTGGATTACCGAAC
TGGAGAAGTAACTGTAACTCAGTAA

Domains

Predicted by InterproScan.

DNA/RNA non-specific endonuclease (Endonuclease_NS)

(75-247)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  endA Streptococcus pneumoniae Rx1

98.175

100

0.982
  endA Streptococcus pneumoniae D39

98.175

100

0.982
  endA Streptococcus pneumoniae R6

98.175

100

0.982
  endA Streptococcus pneumoniae TIGR4

98.175

100

0.982

Multiple sequence alignment