Detailed information NTG1128341

Bioinformatically predicted

Overview

• Name: amiE
• Type: Regulator
• Locus tag: FJH52_RS08900
• Genome accession: NZ_LR595848
• Coordinates: 1786787..1787854 (-)
• Length: 355 a.a.
• NCBI ID: WP_000159554.1
• Uniprot ID: A0A062WMA1
• Organism: Streptococcus pneumoniae strain 4559 isolate 4559
• Function: internalize XIP (predicted from homology) Competence regulation

Genomic Context

Location: 1781787..1792854

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FJH52_RS08885	treR	1783584..1784294 (+)	711	WP_000760673.1	trehalose operon repressor	Regulator
FJH52_RS08890	-	1784449..1785775 (+)	1327	Protein_1778	ISL3 family transposase	-
FJH52_RS08895	amiF	1785850..1786776 (-)	927	WP_001291293.1	ATP-binding cassette domain-containing protein	Regulator
FJH52_RS08900	amiE	1786787..1787854 (-)	1068	WP_000159554.1	ABC transporter ATP-binding protein	Regulator
FJH52_RS08905	amiD	1787863..1788789 (-)	927	WP_000103697.1	oligopeptide ABC transporter permease OppC	Regulator
FJH52_RS08910	amiC	1788789..1790285 (-)	1497	WP_000759902.1	ABC transporter permease	Regulator
FJH52_RS08915	amiA3	1790352..1792331 (-)	1980	WP_000742232.1	peptide ABC transporter substrate-binding protein	Regulator

Sequence

Protein

• Length: 355 a.a.
• Molecular weight: 39490.09 Da
• Isoelectric Point: 4.8727

>NTDB_id=1128341 FJH52_RS08900 WP_000159554.1 1786787..1787854(-) (amiE) [Streptococcus pneumoniae strain 4559 isolate 4559]
MTKEKNVILTARDIVVEFDVRDKVLTAIRGVSLELVEGEVLALVGESGSGKSVLTKTFTGMLEENGRIAQGSIDYRGQDL
TALSSHKDWEQIRGAKIATIFQDPMTSLDPIKTIGSQITEVIVKHQGKTAKEAKELAIDYMNKVGIPDADRRFNEYPFQY
SGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLQNEYHFTTIFITHDLGVVASIADKVAVMYAGEIVE
YGTVEEVFYDPRHPYTWSLLSSLPQLADDKGDLYSIPGTPPSLYTDLKGDAFALRSDYAMQIDFEQKAPQFSVSETHWAK
TWLLHEDAPKVEKPAVIANLHDKIREKMGFAHLAD

Nucleotide

• Length: 1068 bp

>NTDB_id=1128341 FJH52_RS08900 WP_000159554.1 1786787..1787854(-) (amiE) [Streptococcus pneumoniae strain 4559 isolate 4559]
ATGACAAAAGAAAAAAATGTAATTTTGACTGCTCGCGATATTGTCGTGGAATTTGACGTTCGTGACAAAGTATTGACAGC
CATTCGCGGCGTTTCCCTTGAACTAGTTGAAGGAGAAGTATTAGCCTTGGTAGGTGAGTCAGGATCAGGTAAATCTGTTT
TGACAAAGACCTTCACAGGTATGCTCGAAGAAAATGGTCGCATTGCCCAAGGTAGTATTGACTACCGTGGTCAGGATTTG
ACAGCTTTATCTTCTCACAAGGATTGGGAACAAATTCGTGGTGCTAAGATTGCGACTATCTTCCAGGACCCAATGACTAG
TTTGGACCCCATTAAAACAATTGGTAGTCAGATTACAGAAGTTATTGTAAAACACCAAGGAAAAACAGCTAAAGAAGCGA
AAGAATTGGCCATTGACTACATGAATAAGGTTGGCATTCCAGACGCAGATAGACGTTTTAATGAATACCCATTCCAATAT
TCTGGAGGAATGCGTCAACGTATCGTTATTGCTATTGCCCTTGCCTGCCGACCTGATGTCTTGATCTGTGATGAGCCAAC
AACTGCCTTGGATGTAACTATTCAAGCTCAGATTATTGATTTGCTAAAATCTTTACAAAACGAGTATCATTTCACAACAA
TCTTTATTACCCACGACCTTGGTGTGGTGGCAAGTATTGCGGATAAGGTAGCGGTTATGTATGCAGGAGAAATCGTTGAG
TATGGAACGGTTGAGGAAGTCTTCTATGACCCTCGCCATCCATATACATGGAGTCTCTTGTCTAGCTTGCCTCAGCTTGC
TGATGATAAAGGGGATCTTTACTCAATCCCAGGAACACCTCCGTCACTTTATACTGACCTGAAAGGGGATGCTTTTGCCT
TGCGTTCTGACTACGCAATGCAGATTGACTTCGAACAAAAAGCTCCTCAATTCTCAGTATCAGAGACACATTGGGCTAAA
ACTTGGCTTCTTCATGAGGATGCTCCAAAAGTAGAAAAACCAGCTGTGATTGCAAATCTCCATGATAAGATCCGTGAAAA
AATGGGATTTGCCCATCTGGCTGACTAG

Domains

Predicted by InterproScan.

• Oligopeptide/dipeptide transporter, C-terminal region (oligo_HPY) (239-301)

• ABC transporter (ABC_tran) (29-187)

3D structure

• AlphaFold DB: A0A062WMA1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
amiE	Streptococcus salivarius strain HSISS4	88.169	100	0.882
amiE	Streptococcus thermophilus LMG 18311	86.479	100	0.865
amiE	Streptococcus thermophilus LMD-9	86.479	100	0.865
oppD	Streptococcus mutans UA159	54.545	99.155	0.541