Detailed information NTG1128155

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: FGL17_RS09160
• Genome accession: NZ_LR594052
• Coordinates: 1850793..1853234 (-)
• Length: 813 a.a.
• NCBI ID: WP_093959022.1
• Uniprot ID: A0A4V0HD83
• Organism: Streptococcus porcinus strain NCTC10924
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 1845793..1858234

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FGL17_RS09150 (NCTC10924_01844)	groL	1848691..1850319 (-)	1629	WP_003084572.1	chaperonin GroEL	-
FGL17_RS09155 (NCTC10924_01845)	groES	1850361..1850651 (-)	291	WP_039984709.1	co-chaperone GroES	-
FGL17_RS09160 (NCTC10924_01846)	clpC	1850793..1853234 (-)	2442	WP_093959022.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
FGL17_RS09165 (NCTC10924_01847)	-	1853234..1853695 (-)	462	WP_003085318.1	CtsR family transcriptional regulator	-
FGL17_RS09170	-	1853866..1854069 (-)	204	WP_003085753.1	cold-shock protein	-
FGL17_RS09175 (NCTC10924_01849)	-	1854418..1854687 (+)	270	WP_003083519.1	hypothetical protein	-
FGL17_RS09180 (NCTC10924_01850)	-	1854690..1856759 (+)	2070	WP_093959023.1	cation:proton antiporter	-
FGL17_RS09185 (NCTC10924_01851)	-	1856878..1857840 (+)	963	WP_093959024.1	ring-cleaving dioxygenase	-

Sequence

Protein

• Length: 813 a.a.
• Molecular weight: 90237.72 Da
• Isoelectric Point: 5.6873

>NTDB_id=1128155 FGL17_RS09160 WP_093959022.1 1850793..1853234(-) (clpC) [Streptococcus porcinus strain NCTC10924]
MIDYSLKMQEIFKQAQYQAARFDSQYLETWHLLLAMVVVNNSLAGLVFNEFDDKVAIEEYEAAAILAMGQTPNDDVKEWA
LKGQSRTLTKILQFSDAIRQVTGAQEVGSEHVLFAILLNPDVMAARLLEMAGFKLRDEGQGDLKISDLRKAIERQAAYSK
EIIKAIYELRKPKKSKAGGTFSDMMKPASSAGELSDFTRDLTQMASQGLLEPVIGRDKEITRMVQVLSRKTKNNPVLVGD
AGVGKTALAYGLAQRIVEGAIPYELQDMRVLELDMMSVVAGTRFRGDFEERMNQIIDDIEADGKIILFVDELHTIMGSGS
GIDSTLDAANILKPALSRGTLHMVGATTQEEYQKHIEKDAALSRRFAKILIEEPSLEDAYKILLGLKSSYEMYHNVSISD
QAVKVAVKVAHRYLTSKNLPDSAIDLLDEASATVQGLIKKETPSFLSPIDQAILDGNFKKVASLLKAGQKTKPNPTPVTE
DDIMATLSKLSGIPLEKISQADSQKYLRLEEELHKRVIGQDEAISAISRAIRRNQSGIRTGKRPIGSFMFLGPTGVGKTE
LAKALAEVLFDDESALIRFDMSEYMEKFSASRLNGAPPGYVGYDEGGELTEKVRNRPYSVLLFDEVEKAHPDIFNVLLQV
LDDGVLTDSRGRKVDFTNTIIIMTSNLGATALRDDKTVGFGARDISQDHQAMEKRILEELKKAYRPEFINRIDEKVVFHS
LTQDDMQQVVRIMVKPLVAALEEKGIALKFQPSALKYLSEKGYDIEMGARPLRRTIQTEVEDKLSELLLSGQLASGNKLK
VGLTKGKIKCDIE

Nucleotide

• Length: 2442 bp

>NTDB_id=1128155 FGL17_RS09160 WP_093959022.1 1850793..1853234(-) (clpC) [Streptococcus porcinus strain NCTC10924]
ATGATAGATTATTCACTTAAAATGCAGGAAATTTTCAAGCAGGCTCAATATCAAGCGGCACGCTTTGATAGCCAATATTT
AGAAACATGGCATCTTCTTTTAGCAATGGTTGTGGTTAACAATTCACTCGCTGGACTTGTCTTCAATGAATTTGATGATA
AAGTTGCTATAGAAGAATATGAAGCAGCAGCTATTTTGGCTATGGGACAAACGCCAAATGATGATGTGAAAGAATGGGCT
TTAAAAGGTCAGTCTAGAACTTTAACAAAAATTCTCCAGTTTTCAGATGCTATCCGTCAAGTAACGGGTGCCCAGGAAGT
GGGATCAGAACACGTGCTTTTTGCAATATTGTTGAACCCTGATGTGATGGCAGCACGTTTGCTTGAAATGGCTGGTTTTA
AACTAAGAGATGAGGGACAAGGGGACTTGAAAATCTCTGATTTACGTAAAGCAATTGAAAGACAGGCTGCCTATAGCAAA
GAGATTATTAAAGCTATTTATGAATTACGCAAACCTAAAAAATCAAAAGCGGGTGGGACATTCTCAGATATGATGAAACC
GGCAAGTTCAGCAGGTGAACTTTCTGATTTCACACGTGATTTAACGCAAATGGCCAGTCAAGGACTTTTAGAACCGGTGA
TTGGTCGAGATAAAGAAATTACCCGAATGGTTCAGGTATTGAGCCGCAAGACTAAGAATAATCCGGTCTTAGTTGGAGAT
GCGGGTGTTGGGAAAACGGCTTTGGCATATGGACTAGCTCAACGAATTGTCGAGGGGGCTATTCCCTACGAATTGCAGGA
TATGCGAGTTTTGGAATTGGACATGATGAGTGTGGTTGCAGGAACTCGTTTTCGTGGAGATTTTGAAGAGCGAATGAATC
AAATCATAGATGATATTGAAGCTGATGGGAAAATCATTCTTTTTGTTGATGAGTTACATACGATTATGGGTTCAGGAAGT
GGTATTGATAGTACCTTAGATGCGGCTAACATTTTGAAACCAGCCTTGTCTCGCGGAACGCTACATATGGTAGGTGCAAC
AACTCAGGAAGAATATCAAAAACATATTGAAAAAGATGCAGCTCTATCTCGTCGTTTTGCTAAAATTTTAATTGAAGAAC
CAAGCCTTGAAGATGCTTACAAAATTCTTCTTGGTCTAAAATCTTCTTATGAGATGTATCATAATGTTAGTATTTCTGAT
CAGGCTGTCAAAGTGGCTGTTAAAGTTGCACATCGTTATTTAACTAGTAAAAACCTGCCAGATTCTGCTATAGACCTCTT
AGATGAGGCAAGTGCAACTGTCCAGGGACTAATAAAAAAAGAGACCCCATCCTTTTTAAGCCCTATTGATCAAGCTATCC
TAGATGGGAATTTTAAAAAAGTGGCTAGTTTGTTAAAAGCCGGTCAGAAAACAAAGCCCAATCCAACCCCAGTTACAGAA
GATGATATTATGGCAACTTTGAGTAAACTATCAGGGATACCGCTAGAGAAAATTAGTCAAGCTGATAGCCAAAAATACCT
TCGTTTAGAGGAAGAATTACACAAACGCGTTATTGGTCAAGACGAAGCTATTTCAGCTATTTCAAGGGCTATACGTCGTA
ATCAATCTGGTATTCGAACTGGCAAACGCCCAATCGGTTCATTTATGTTTCTAGGTCCAACAGGTGTTGGGAAAACAGAG
CTGGCTAAAGCCTTGGCTGAGGTTTTATTTGATGATGAATCAGCATTAATTCGTTTTGATATGTCAGAGTACATGGAAAA
ATTTTCAGCCAGTCGTCTTAATGGTGCCCCTCCAGGATATGTGGGCTATGACGAGGGTGGAGAATTGACAGAAAAAGTAA
GAAATAGACCTTACTCCGTTTTGCTCTTTGATGAAGTTGAAAAAGCTCATCCAGATATTTTCAACGTTCTTCTTCAAGTT
TTGGATGATGGGGTGCTGACAGATTCTCGCGGTCGCAAAGTTGACTTCACGAATACTATTATTATCATGACTAGCAATTT
AGGTGCAACAGCACTTCGAGATGATAAGACTGTAGGTTTTGGTGCTCGAGATATTAGCCAAGATCACCAAGCTATGGAAA
AACGTATTTTAGAAGAACTAAAGAAAGCTTATCGTCCTGAATTTATTAATCGAATTGATGAAAAGGTTGTTTTCCACAGT
TTAACTCAAGATGATATGCAACAAGTAGTGAGGATTATGGTGAAACCGTTAGTTGCTGCCTTAGAAGAAAAGGGAATTGC
TCTAAAATTCCAGCCGTCAGCACTTAAATACCTATCTGAAAAAGGTTATGATATTGAAATGGGAGCTCGTCCTCTTCGAA
GAACGATTCAAACAGAAGTTGAGGATAAATTGTCAGAGTTACTCCTTTCGGGACAGTTAGCTTCTGGAAATAAATTAAAA
GTTGGTTTAACTAAAGGTAAAATAAAATGTGACATAGAATAA

Domains

Predicted by InterproScan.

• AAA lid domain (AAA_lid_9) (375-452)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (721-801)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (18-51)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (101-134)

• AAA domain (Cdc48 subfamily) (AAA_2) (543-714)

• ATPase family associated with various cellular activities (AAA) (AAA) (236-368)

3D structure

• AlphaFold DB: A0A4V0HD83

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Streptococcus mutans UA159	73.801	100	0.738
clpC	Streptococcus thermophilus LMD-9	72.604	100	0.727
clpC	Streptococcus thermophilus LMG 18311	72.604	100	0.727
clpC	Streptococcus pneumoniae TIGR4	65.437	100	0.654
clpC	Streptococcus pneumoniae Rx1	65.437	100	0.654
clpC	Streptococcus pneumoniae D39	65.437	100	0.654
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	47.904	100	0.492
clpC	Bacillus subtilis subsp. subtilis str. 168	44.471	100	0.46
clpE	Streptococcus pneumoniae Rx1	45.666	79.459	0.363
clpE	Streptococcus pneumoniae D39	45.666	79.459	0.363
clpE	Streptococcus pneumoniae R6	45.666	79.459	0.363
clpE	Streptococcus pneumoniae TIGR4	45.666	79.459	0.363