Detailed information NTG1128033

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: FGL20_RS02535
• Genome accession: NZ_LR594050
• Coordinates: 492645..493688 (+)
• Length: 347 a.a.
• NCBI ID: WP_003082628.1
• Uniprot ID: A0A4V0GZT7
• Organism: Streptococcus porcinus strain NCTC10925
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 487645..498688

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FGL20_RS02510 (NCTC10925_00507)	-	488067..489398 (+)	1332	WP_093958901.1	dipeptidase	-
FGL20_RS02515 (NCTC10925_00508)	arcC	489415..490365 (+)	951	WP_003082752.1	carbamate kinase	-
FGL20_RS02520 (NCTC10925_00509)	asnA	490544..491536 (+)	993	WP_093958900.1	aspartate--ammonia ligase	-
FGL20_RS02525 (NCTC10925_00510)	rsmD	491638..492177 (+)	540	WP_093958899.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
FGL20_RS02530 (NCTC10925_00511)	coaD	492167..492658 (+)	492	WP_093958898.1	pantetheine-phosphate adenylyltransferase	-
FGL20_RS02535 (NCTC10925_00512)	sepM	492645..493688 (+)	1044	WP_003082628.1	SepM family pheromone-processing serine protease	Regulator
FGL20_RS02540 (NCTC10925_00513)	-	493818..495773 (+)	1956	WP_003084642.1	BglG family transcription antiterminator	-
FGL20_RS02545 (NCTC10925_00514)	-	495801..496274 (+)	474	WP_039985002.1	PTS sugar transporter subunit IIA	-
FGL20_RS02550 (NCTC10925_00515)	-	496276..496554 (+)	279	WP_003083266.1	PTS sugar transporter subunit IIB	-
FGL20_RS02555 (NCTC10925_00516)	-	496566..497906 (+)	1341	WP_003085397.1	PTS galactitol transporter subunit IIC	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 38318.33 Da
• Isoelectric Point: 10.1692

>NTDB_id=1128033 FGL20_RS02535 WP_003082628.1 492645..493688(+) (sepM) [Streptococcus porcinus strain NCTC10925]
MKIIKKVKWWLISILAVVALLFALFFPLPYYIEMPGGAYDIRSVLQINNKKDKEKGSYNFVAVSLSRATFAQILYAWVTP
FTEISSVENTTGGYSAADYMRINQYYMETSQNGAIYQALKLAGKPVSLDYLGVYVLDVNKDSTFRGVLNIADTVTGVNKK
EFKSSADLIKYVSSLKRGEQVTVQYTTGNEKRSKSGKVIKLKNGKNGIGIGLTDHTKVHTDEKIEFSTEGVGGPSAGLMF
TLDIYDQLNQENLRKGRRIAGTGTIDQDGKVGDIGGAGLKVVAAAKEGAEIFFVPNNPVDKRIKKVKPNAKTNYKEALDV
AKKLKTKMKIVPVRNVKEAIAYLQKTE

Nucleotide

• Length: 1044 bp

>NTDB_id=1128033 FGL20_RS02535 WP_003082628.1 492645..493688(+) (sepM) [Streptococcus porcinus strain NCTC10925]
ATGAAGATAATTAAAAAAGTCAAATGGTGGTTAATTAGTATTCTGGCAGTAGTTGCCCTCTTATTTGCCCTCTTTTTCCC
TTTACCTTATTATATTGAGATGCCTGGCGGCGCTTACGATATTCGTTCAGTACTCCAGATAAACAATAAGAAGGATAAGG
AAAAAGGCTCTTACAATTTTGTAGCAGTTAGTTTGAGTCGAGCTACCTTTGCGCAAATCCTTTATGCTTGGGTAACGCCA
TTTACAGAGATTTCATCTGTAGAAAATACAACTGGTGGTTACAGTGCGGCAGATTATATGCGTATAAATCAATATTACAT
GGAGACCTCTCAAAATGGAGCTATCTACCAAGCTTTAAAATTAGCTGGAAAACCTGTTTCATTAGACTATTTAGGTGTTT
ATGTTTTGGATGTTAATAAAGATTCAACTTTTCGTGGTGTTTTAAATATTGCAGATACAGTTACAGGAGTCAATAAAAAG
GAATTTAAAAGTTCAGCTGATCTCATTAAGTACGTTTCAAGTTTGAAACGAGGTGAACAGGTCACGGTTCAATATACTAC
TGGTAATGAGAAAAGATCCAAAAGTGGTAAGGTCATTAAGCTAAAAAACGGTAAAAATGGTATTGGTATTGGTTTAACAG
ACCACACAAAAGTACATACAGACGAAAAAATTGAGTTTTCAACAGAAGGTGTAGGTGGGCCAAGTGCTGGACTTATGTTT
ACACTGGATATTTATGATCAACTGAATCAAGAAAATCTGCGTAAAGGTCGTCGTATTGCAGGTACTGGAACAATTGATCA
AGATGGTAAAGTTGGTGATATTGGTGGTGCAGGTTTAAAAGTCGTGGCTGCAGCCAAGGAAGGTGCAGAGATTTTCTTCG
TGCCTAATAACCCAGTTGATAAGCGTATCAAAAAAGTGAAGCCAAATGCAAAGACCAATTACAAAGAGGCCTTAGATGTA
GCAAAAAAATTAAAAACCAAGATGAAAATCGTCCCAGTTAGAAATGTTAAAGAAGCTATTGCTTATTTGCAAAAGACTGA
ATAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (131-192)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (232-340)

3D structure

• AlphaFold DB: A0A4V0GZT7

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	71.304	99.424	0.709