Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpE   Type   Regulator
Locus tag   FGL23_RS03365 Genome accession   NZ_LR594049
Coordinates   708821..711052 (-) Length   743 a.a.
NCBI ID   WP_061604076.1    Uniprot ID   -
Organism   Streptococcus gordonii strain NCTC10231     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 703821..716052
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FGL23_RS03335 (NCTC10231_00666) - 705225..705641 (-) 417 WP_060554050.1 MarR family winged helix-turn-helix transcriptional regulator -
  FGL23_RS03340 (NCTC10231_00667) - 705703..706140 (+) 438 WP_060554049.1 GNAT family N-acetyltransferase -
  FGL23_RS03345 (NCTC10231_00668) - 706177..706476 (-) 300 WP_060554048.1 DUF1827 family protein -
  FGL23_RS03350 (NCTC10231_00669) - 706575..707027 (-) 453 WP_061604073.1 NUDIX hydrolase -
  FGL23_RS03355 (NCTC10231_00670) - 707185..708075 (+) 891 WP_061604074.1 helix-turn-helix transcriptional regulator -
  FGL23_RS03360 (NCTC10231_00671) - 708135..708740 (+) 606 WP_061604075.1 GyrI-like domain-containing protein -
  FGL23_RS03365 (NCTC10231_00672) clpE 708821..711052 (-) 2232 WP_061604076.1 ATP-dependent Clp protease ATP-binding subunit Regulator
  FGL23_RS03370 (NCTC10231_00673) - 711305..711535 (+) 231 WP_008809091.1 DUF1797 family protein -
  FGL23_RS03375 (NCTC10231_00674) - 711668..712522 (+) 855 WP_138115421.1 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase -
  FGL23_RS03380 (NCTC10231_00675) - 712519..713292 (+) 774 WP_061604078.1 HAD hydrolase family protein -
  FGL23_RS03385 (NCTC10231_00676) - 713400..714242 (+) 843 WP_060554042.1 NAD(P)H-hydrate dehydratase -
  FGL23_RS03395 (NCTC10231_00677) xseA 714398..715738 (+) 1341 WP_060554041.1 exodeoxyribonuclease VII large subunit -
  FGL23_RS03400 (NCTC10231_00678) - 715716..715928 (+) 213 WP_060554040.1 exodeoxyribonuclease VII small subunit -

Sequence

Protein


Download         Length: 743 a.a.        Molecular weight: 82916.96 Da        Isoelectric Point: 5.0186

>NTDB_id=1127959 FGL23_RS03365 WP_061604076.1 708821..711052(-) (clpE) [Streptococcus gordonii strain NCTC10231]
MLCQNCKINESTIHLYTNVNGKKQQVDLCQNCYQIMKTDPNNSLLSGLTNMNNHNMDPFDDFFNHLGNFQGPKDSTPPTQ
SGGSYGGGNYGPGSNNQHPQSASNKPKGLLEEFGINVTEIARRGDIDPVIGRDDEIRRVIEILNRRTKNNPVLIGEPGVG
KTAVVEGLAQKIVDSDVPQKLQGKEVIRLDVVSLVQGTGIRGQFEERMQKLMDEIRNRNDIILFIDEIHEIVGAGSAGDG
NMDAGNILKPALARGELQLVGATTLNEYRIIEKDAALERRMQPVKVDEPTVEETITILKGIQKKYEDYHHVRYTDEAIEA
AAILSNRYIQDRFLPDKAIDLLDESGSKMNLTLNFVDPKEIDRRLIEAENLKTQATRDEDYEKAAYFRDQIAKYKEMQTA
KIDEQDTPIISEKEIEAIVEQKTNIPVGDLKEKEQSQLIHLASDLKSHVIGQDDAVDKIAKAIRRNRVGLGSPNRPIGSF
LFVGPTGVGKTELSKQLAIELFGSADSMIRFDMSEYMEKHSVAKLVGAPPGYVGYEEAGQLTERVRRNPYSLILLDEVEK
AHPDVMHMFLQVLDDGRLTDGQGRTVSFKDTIIIMTSNAGTGKVEASVGFGAAREGRTNSVLGELGNFFSPEFMNRFDGI
IEFKALSKDNLLQIVDLMLEDVNNRLASNEIHLDVTTKVKEKLVDLGYDPKMGARPLRRTIQDYIEDAITDYYLEHPTDK
DLKAIMTSNGKIIIKGKQKAELD

Nucleotide


Download         Length: 2232 bp        

>NTDB_id=1127959 FGL23_RS03365 WP_061604076.1 708821..711052(-) (clpE) [Streptococcus gordonii strain NCTC10231]
ATGCTTTGTCAAAACTGTAAAATCAATGAATCTACCATTCATTTATACACTAATGTAAATGGTAAAAAACAACAAGTCGA
CCTCTGTCAAAATTGCTATCAGATTATGAAAACTGATCCAAATAACTCTCTTTTGAGTGGACTGACGAACATGAACAATC
ATAATATGGATCCTTTTGATGATTTCTTTAATCATCTGGGGAATTTCCAAGGGCCGAAGGATTCTACCCCTCCAACTCAG
TCAGGTGGTAGTTACGGAGGGGGCAACTATGGTCCTGGTTCTAACAACCAGCATCCTCAGTCAGCTTCCAATAAACCAAA
AGGTCTTTTGGAAGAGTTTGGCATTAACGTTACAGAAATTGCTCGACGTGGTGATATTGATCCAGTGATTGGACGAGATG
ATGAAATTCGTCGTGTTATAGAAATTCTCAATCGCCGAACTAAGAATAATCCAGTCCTTATTGGCGAACCTGGTGTCGGC
AAGACTGCTGTTGTAGAGGGCTTGGCACAGAAAATAGTCGATAGTGACGTTCCTCAAAAACTGCAAGGAAAAGAGGTCAT
TCGGCTCGATGTTGTCAGCCTTGTTCAAGGAACTGGTATTCGTGGACAGTTTGAAGAACGAATGCAAAAACTCATGGATG
AGATTCGCAATCGCAATGATATCATTCTCTTTATTGATGAAATCCATGAAATTGTTGGAGCTGGCTCTGCGGGCGACGGT
AATATGGATGCTGGAAATATTCTCAAACCTGCTCTTGCTCGAGGTGAACTTCAACTGGTCGGAGCTACTACTCTCAATGA
ATATCGTATCATTGAAAAAGATGCAGCTTTAGAAAGACGGATGCAACCAGTCAAGGTAGATGAACCAACCGTAGAAGAAA
CGATCACAATTCTAAAGGGAATTCAAAAGAAATACGAAGATTACCACCATGTTCGCTACACAGATGAAGCTATTGAAGCT
GCTGCCATCCTATCCAATCGTTATATTCAGGACCGTTTCCTTCCCGATAAAGCTATTGATCTTTTGGATGAATCAGGATC
TAAGATGAACCTAACCCTCAATTTTGTTGATCCAAAAGAAATTGACAGACGCTTGATAGAGGCTGAAAATCTGAAAACAC
AGGCCACTCGCGATGAAGATTACGAAAAAGCAGCCTACTTCCGCGACCAAATTGCCAAATATAAGGAAATGCAAACTGCT
AAAATAGATGAACAAGATACTCCTATCATCAGTGAGAAGGAGATCGAGGCTATTGTAGAGCAAAAAACAAATATTCCAGT
TGGCGACTTGAAGGAAAAAGAACAGTCTCAACTTATTCATTTAGCCAGTGATTTGAAGTCTCATGTCATTGGGCAGGATG
ATGCTGTTGATAAGATTGCAAAAGCCATCCGTCGTAATCGTGTGGGATTAGGCAGTCCAAACCGGCCAATCGGAAGTTTC
CTTTTTGTTGGACCGACAGGCGTTGGAAAAACTGAACTTTCCAAACAATTGGCCATCGAACTTTTTGGCTCGGCCGATAG
CATGATTCGTTTTGATATGAGTGAATACATGGAAAAACATAGTGTTGCCAAACTTGTGGGAGCACCTCCAGGCTACGTTG
GCTATGAAGAAGCAGGCCAGTTGACTGAACGTGTTCGTCGTAATCCATACTCACTCATTCTCCTAGATGAGGTGGAAAAA
GCTCATCCAGATGTCATGCATATGTTCTTACAAGTCCTAGATGATGGACGTTTGACTGATGGTCAAGGTAGGACAGTCAG
CTTCAAAGATACCATTATTATCATGACTTCCAATGCAGGAACTGGCAAAGTGGAAGCTAGCGTTGGCTTTGGTGCTGCTC
GAGAAGGTCGGACAAATTCTGTCTTAGGTGAGTTAGGTAACTTCTTTAGTCCAGAATTCATGAATCGATTTGATGGTATC
ATTGAATTCAAGGCATTAAGCAAGGATAATCTCTTACAGATTGTGGATCTAATGCTGGAAGATGTTAATAATCGACTCGC
TAGCAACGAAATTCATCTAGATGTAACAACTAAAGTCAAAGAAAAATTGGTTGATCTGGGCTACGATCCTAAGATGGGGG
CACGACCACTCCGTAGAACTATTCAGGATTATATCGAAGATGCTATTACGGACTACTACCTAGAACATCCGACAGATAAG
GATTTAAAAGCAATTATGACTAGCAATGGCAAGATTATAATTAAGGGTAAACAAAAAGCTGAGCTTGATTAA

Domains

Predicted by InterproScan.

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(646-718)

AAA domain (Cdc48 subfamily) (AAA_2)

(475-638)

AAA lid domain (AAA_lid_9)

(290-387)

ATPase family associated with various cellular activities (AAA) (AAA)

(152-271)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpE Streptococcus pneumoniae Rx1

86.863

100

0.872
  clpE Streptococcus pneumoniae D39

86.863

100

0.872
  clpE Streptococcus pneumoniae R6

86.863

100

0.872
  clpE Streptococcus pneumoniae TIGR4

86.729

100

0.871
  clpE Streptococcus mutans UA159

84.987

100

0.853
  clpC Lactococcus lactis subsp. cremoris KW2

78.138

99.731

0.779
  clpC Bacillus subtilis subsp. subtilis str. 168

50.444

90.983

0.459
  clpC Streptococcus pneumoniae Rx1

47.68

84.118

0.401
  clpC Streptococcus pneumoniae D39

47.68

84.118

0.401
  clpC Streptococcus pneumoniae TIGR4

47.52

84.118

0.4
  clpC Streptococcus thermophilus LMD-9

44.985

88.56

0.398
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

46.603

85.195

0.397
  clpC Streptococcus thermophilus LMG 18311

44.681

88.56

0.396
  clpC Streptococcus mutans UA159

47.343

83.58

0.396

Multiple sequence alignment