Detailed information NTG1127929

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: FGL22_RS07765
• Genome accession: NZ_LR594048
• Coordinates: 1557512..1558549 (-)
• Length: 345 a.a.
• NCBI ID: WP_065355406.1
• Uniprot ID: A0AB38XZ54
• Organism: Streptococcus dysgalactiae subsp. equisimilis strain NCTC11556
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1552512..1563549

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FGL22_RS07740 (NCTC11556_01606)	-	1552944..1554173 (+)	1230	WP_003054206.1	IS110 family transposase	-
FGL22_RS11180 (NCTC11556_01607)	-	1554400..1554761 (-)	362	Protein_1465	ATP-binding cassette domain-containing protein	-
FGL22_RS11090 (NCTC11556_01608)	-	1554776..1554955 (-)	180	WP_003053686.1	ATP-binding cassette domain-containing protein	-
FGL22_RS07750 (NCTC11556_01609)	rbsD	1554971..1555369 (-)	399	WP_003051896.1	D-ribose pyranase	-
FGL22_RS07755 (NCTC11556_01610)	rbsK	1555344..1556255 (-)	912	WP_003053680.1	ribokinase	-
FGL22_RS07760 (NCTC11556_01611)	-	1556248..1557231 (-)	984	WP_003053684.1	LacI family DNA-binding transcriptional regulator	-
FGL22_RS07765 (NCTC11556_01612)	sepM	1557512..1558549 (-)	1038	WP_065355406.1	SepM family pheromone-processing serine protease	Regulator
FGL22_RS07770 (NCTC11556_01613)	coaD	1558536..1559027 (-)	492	WP_003051905.1	pantetheine-phosphate adenylyltransferase	-
FGL22_RS07775 (NCTC11556_01614)	rsmD	1559017..1559556 (-)	540	WP_014612463.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
FGL22_RS07780 (NCTC11556_01615)	asnA	1559750..1560742 (-)	993	WP_065355407.1	aspartate--ammonia ligase	-
FGL22_RS07785 (NCTC11556_01616)	arcC	1561068..1562018 (-)	951	WP_014612465.1	carbamate kinase	-

Sequence

Protein

• Length: 345 a.a.
• Molecular weight: 37630.20 Da
• Isoelectric Point: 9.4270

>NTDB_id=1127929 FGL22_RS07765 WP_065355406.1 1557512..1558549(-) (sepM) [Streptococcus dysgalactiae subsp. equisimilis strain NCTC11556]
MKTIKKIKWWLINLIALVALLIVLFFPLPYYVEMPGGAYDIRSVVKVNGKEDKDKGSYQFVAVSLSRASLAQLLYAWLTP
FTEISSVEDTTGGYSDADYIRINQFYMETSQNAAVYQALTLADKPVTLDYKGVYVLDISKDSTFKGTLNLADTVTGVNHK
QFTSSTELVDYVSHLKLGDKVTVQFISNSEPKSETGRIIKLKNGKNGIGIALTDHTKVNSAEKIEFSTQGVGGPSAGLMF
TLDIYDQINKEDLRKGRHIAGTGTIGKDGEVGDIGGAGLKVVAAADAGAEIFFVPNNPVDKAVKKANPKAISNYEEAKRA
AKQLKTKMKIVPVTTVQDALAYLRQ

Nucleotide

• Length: 1038 bp

>NTDB_id=1127929 FGL22_RS07765 WP_065355406.1 1557512..1558549(-) (sepM) [Streptococcus dysgalactiae subsp. equisimilis strain NCTC11556]
ATGAAAACAATTAAAAAAATTAAATGGTGGCTGATTAATCTAATTGCCCTCGTGGCTCTGCTTATCGTCCTTTTTTTCCC
TCTTCCTTATTATGTTGAAATGCCTGGCGGAGCCTATGACATTCGATCTGTGGTCAAGGTTAATGGCAAAGAAGATAAAG
ATAAAGGCTCCTATCAGTTTGTGGCAGTCAGTCTCAGTCGAGCCAGTTTAGCTCAGTTGCTCTATGCTTGGCTAACCCCT
TTTACTGAAATCAGTTCAGTTGAGGATACCACAGGCGGTTATAGCGATGCAGACTATATCCGCATTAATCAATTCTACAT
GGAAACCTCACAAAATGCTGCGGTCTATCAGGCATTGACCTTGGCAGACAAACCAGTTACTTTGGACTACAAAGGGGTAT
ATGTGTTAGATATTAGCAAGGATTCAACCTTTAAAGGTACTTTAAACTTAGCAGATACGGTAACGGGAGTGAATCACAAA
CAATTTACGAGTTCAACAGAACTTGTGGACTATGTCTCTCATTTAAAACTTGGTGATAAGGTGACTGTGCAGTTTATTAG
TAACAGCGAACCTAAGTCTGAAACAGGTCGTATCATCAAACTAAAAAATGGTAAAAATGGTATCGGCATTGCTTTAACAG
ACCATACTAAAGTCAATTCAGCAGAGAAAATCGAGTTTAGTACCCAAGGTGTTGGGGGTCCTAGCGCAGGCTTAATGTTT
ACATTAGATATCTACGACCAAATTAATAAAGAAGACCTTCGTAAAGGAAGACATATCGCCGGGACAGGAACCATTGGTAA
AGATGGTGAAGTTGGAGATATTGGCGGTGCGGGTCTTAAGGTCGTTGCTGCTGCAGATGCTGGTGCTGAGATTTTCTTTG
TGCCGAATAATCCTGTGGATAAAGCTGTTAAAAAAGCCAATCCAAAAGCTATTAGCAATTATGAAGAGGCCAAGCGAGCA
GCCAAGCAGTTAAAAACAAAAATGAAAATTGTTCCTGTAACAACTGTTCAGGATGCCCTAGCCTACCTTCGTCAATAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (130-192)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (233-299)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	71.304	100	0.713