Detailed information NTG1127869

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: FGL21_RS08025
• Genome accession: NZ_LR594047
• Coordinates: 1592895..1593932 (-)
• Length: 345 a.a.
• NCBI ID: WP_065355406.1
• Uniprot ID: A0AB38XZ54
• Organism: Streptococcus dysgalactiae subsp. equisimilis strain NCTC11554
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1587895..1598932

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FGL21_RS08000 (NCTC11554_01676)	-	1588327..1589556 (+)	1230	WP_003054206.1	IS110 family transposase	-
FGL21_RS11560 (NCTC11554_01677)	-	1589783..1590144 (-)	362	Protein_1505	ATP-binding cassette domain-containing protein	-
FGL21_RS11425 (NCTC11554_01678)	-	1590159..1590338 (-)	180	WP_003053686.1	ATP-binding cassette domain-containing protein	-
FGL21_RS08010 (NCTC11554_01679)	rbsD	1590354..1590752 (-)	399	WP_003051896.1	D-ribose pyranase	-
FGL21_RS08015 (NCTC11554_01680)	rbsK	1590727..1591638 (-)	912	WP_003053680.1	ribokinase	-
FGL21_RS08020 (NCTC11554_01681)	-	1591631..1592614 (-)	984	WP_003053684.1	LacI family DNA-binding transcriptional regulator	-
FGL21_RS08025 (NCTC11554_01682)	sepM	1592895..1593932 (-)	1038	WP_065355406.1	SepM family pheromone-processing serine protease	Regulator
FGL21_RS08030 (NCTC11554_01683)	coaD	1593919..1594410 (-)	492	WP_003051905.1	pantetheine-phosphate adenylyltransferase	-
FGL21_RS08035 (NCTC11554_01684)	rsmD	1594400..1594939 (-)	540	WP_014612463.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
FGL21_RS08040 (NCTC11554_01685)	asnA	1595133..1596125 (-)	993	WP_003055679.1	aspartate--ammonia ligase	-
FGL21_RS08045 (NCTC11554_01686)	arcC	1596451..1597401 (-)	951	WP_014612465.1	carbamate kinase	-

Sequence

Protein

• Length: 345 a.a.
• Molecular weight: 37630.20 Da
• Isoelectric Point: 9.4270

>NTDB_id=1127869 FGL21_RS08025 WP_065355406.1 1592895..1593932(-) (sepM) [Streptococcus dysgalactiae subsp. equisimilis strain NCTC11554]
MKTIKKIKWWLINLIALVALLIVLFFPLPYYVEMPGGAYDIRSVVKVNGKEDKDKGSYQFVAVSLSRASLAQLLYAWLTP
FTEISSVEDTTGGYSDADYIRINQFYMETSQNAAVYQALTLADKPVTLDYKGVYVLDISKDSTFKGTLNLADTVTGVNHK
QFTSSTELVDYVSHLKLGDKVTVQFISNSEPKSETGRIIKLKNGKNGIGIALTDHTKVNSAEKIEFSTQGVGGPSAGLMF
TLDIYDQINKEDLRKGRHIAGTGTIGKDGEVGDIGGAGLKVVAAADAGAEIFFVPNNPVDKAVKKANPKAISNYEEAKRA
AKQLKTKMKIVPVTTVQDALAYLRQ

Nucleotide

• Length: 1038 bp

>NTDB_id=1127869 FGL21_RS08025 WP_065355406.1 1592895..1593932(-) (sepM) [Streptococcus dysgalactiae subsp. equisimilis strain NCTC11554]
ATGAAAACAATTAAAAAAATTAAATGGTGGCTGATTAATCTAATTGCCCTCGTGGCTCTGCTTATCGTCCTTTTTTTCCC
TCTTCCTTATTATGTTGAAATGCCTGGCGGAGCCTATGACATTCGATCTGTGGTCAAGGTTAATGGCAAAGAAGATAAAG
ATAAAGGCTCCTATCAGTTTGTGGCAGTCAGTCTCAGTCGAGCCAGTTTAGCTCAGTTGCTCTATGCTTGGCTAACCCCT
TTTACTGAAATCAGTTCAGTTGAGGATACCACAGGCGGTTATAGCGATGCAGACTATATCCGCATTAATCAATTCTACAT
GGAAACCTCACAAAATGCTGCGGTCTATCAGGCATTGACCTTGGCAGACAAACCAGTTACTTTGGACTACAAAGGGGTAT
ATGTGTTAGATATTAGCAAGGATTCAACCTTTAAAGGTACTTTAAACTTAGCAGATACGGTAACGGGAGTGAATCACAAA
CAATTTACGAGTTCAACAGAACTTGTGGACTATGTCTCTCATTTAAAACTTGGTGATAAGGTGACTGTGCAGTTTATTAG
TAACAGCGAACCTAAGTCTGAAACAGGTCGTATCATCAAACTAAAAAATGGTAAAAATGGTATCGGCATTGCTTTAACAG
ACCATACTAAAGTCAATTCAGCAGAGAAAATCGAGTTTAGTACCCAAGGTGTTGGGGGTCCTAGCGCAGGCTTAATGTTT
ACATTAGATATCTACGACCAAATTAATAAAGAAGACCTTCGTAAAGGAAGACATATCGCCGGGACAGGAACCATTGGTAA
AGATGGTGAAGTTGGAGATATTGGCGGTGCGGGTCTTAAGGTCGTTGCTGCTGCAGATGCTGGTGCTGAGATTTTCTTTG
TGCCGAATAATCCTGTGGATAAAGCTGTTAAAAAAGCCAATCCAAAAGCTATTAGCAATTATGAAGAGGCCAAGCGAGCA
GCCAAGCAGTTAAAAACAAAAATGAAAATTGTTCCTGTAACAACTGTTCAGGATGCCCTAGCCTACCTTCGTCAATAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (130-192)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (233-299)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	71.304	100	0.713