Detailed information NTG1127822

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: FGL18_RS09855
• Genome accession: NZ_LR594046
• Coordinates: 2040972..2043416 (-)
• Length: 814 a.a.
• NCBI ID: WP_138126725.1
• Uniprot ID: -
• Organism: Streptococcus dysgalactiae strain NCTC6403
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 2035972..2048416

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FGL18_RS09835 (NCTC6403_02022)	-	2036329..2037825 (+)	1497	WP_138126721.1	C69 family dipeptidase	-
FGL18_RS09840 (NCTC6403_02023)	-	2038158..2038625 (+)	468	WP_003060031.1	8-oxo-dGTP diphosphatase	-
FGL18_RS09845 (NCTC6403_02024)	groL	2038843..2040468 (-)	1626	WP_138126723.1	chaperonin GroEL	-
FGL18_RS09850 (NCTC6403_02025)	groES	2040504..2040794 (-)	291	WP_003054738.1	co-chaperone GroES	-
FGL18_RS09855 (NCTC6403_02026)	clpC	2040972..2043416 (-)	2445	WP_138126725.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
FGL18_RS09860 (NCTC6403_02027)	-	2043416..2043877 (-)	462	WP_003054759.1	CtsR family transcriptional regulator	-
FGL18_RS09865	-	2044073..2044276 (-)	204	WP_003053018.1	cold-shock protein	-
FGL18_RS09870 (NCTC6403_02029)	-	2044688..2045662 (+)	975	WP_138126727.1	amidohydrolase family protein	-
FGL18_RS09875 (NCTC6403_02030)	-	2045793..2046248 (+)	456	WP_049519538.1	MarR family transcriptional regulator	-
FGL18_RS09880 (NCTC6403_02031)	-	2046235..2047626 (+)	1392	WP_138126729.1	GNAT family N-acetyltransferase	-
FGL18_RS09885 (NCTC6403_02032)	-	2047742..2048020 (+)	279	WP_138126731.1	GNAT family N-acetyltransferase	-

Sequence

Protein

• Length: 814 a.a.
• Molecular weight: 90246.80 Da
• Isoelectric Point: 6.4813

>NTDB_id=1127822 FGL18_RS09855 WP_138126725.1 2040972..2043416(-) (clpC) [Streptococcus dysgalactiae strain NCTC6403]
MIMYSLKMQEIFRQAQFQAARFDSQYLETWHILLAMARVDHSLAGLVLSEFDAKVAVEEYEAAAILAMGKSPKDQVSHID
FRPQSKTLTNLLQFAQAISQVTKDQEVGSEHVLFAILLNPDIMATRLLEMAGYTIKDKGNGEPRLADLRKAIEIHAGYSK
EIIKAIHELRKPKKTKNQGSFSDMMKPPSTAGDLADFTRDLTEMASQGLLEPVIGRDAEVSRMIQVLSRKTKNNPVLVGD
AGVGKTALAYGLAQRIANGAIPYELQDMRVLELDMMSVVAGTRFRGDFEERMNQIIDDIESDGKIILFVDELHTIMGSGS
GIDSTLDAANILKPALSRGTLHMVGATTQEEYQKHIEKDAALSRRFAKILIEEPNVEDAYQILLGLKGSYETYHNVTIAD
QAVRTAVKMAHRYLTSKNLPDSAIDLLDEASATVQGMVKKSSPEIITPLDQALIDGDMKKASRLLAKDVKGQHRKPTAVT
EEDILTTLSKLSGIPLEKLSQADSKKYLNLEKELHKRVIGQEDAVSAISRAIRRNQSGIRTGKRPIGSFMFLGPTGVGKT
ELAKALAEVLFDDASALIRFDMSEYMEKFAASRLNGAPPGYVGYDEGGELTEKVRNKPYSVLLFDEVEKAHPDIFNVLLQ
VLDDGMLTDSRGRKVDFSNTIIIMTSNLGATALRDDKTVGFGAKGISHDHQAMEKRILEELKKAYRPEFINRIDEKVVFH
SLTQDNMREVVKIMVQPLIATLAEKGITLKFQPMALKYLSEEGYDVEMGARPLRRTLQTQVEDKLSELILAGELASGHTL
KIGLSHGKLSFNIE

Nucleotide

• Length: 2445 bp

>NTDB_id=1127822 FGL18_RS09855 WP_138126725.1 2040972..2043416(-) (clpC) [Streptococcus dysgalactiae strain NCTC6403]
ATGATCATGTATTCATTGAAGATGCAAGAAATTTTCAGACAGGCGCAGTTTCAAGCAGCCCGCTTTGATAGCCAATACCT
AGAAACTTGGCATATATTGCTAGCTATGGCGAGGGTTGATCACTCCCTAGCGGGTTTGGTGCTAAGCGAATTTGATGCTA
AGGTTGCAGTGGAAGAATATGAGGCTGCAGCTATTTTAGCGATGGGCAAAAGCCCTAAAGACCAAGTGTCTCACATTGAC
TTTAGGCCTCAGTCAAAAACCTTAACGAACCTTTTGCAATTTGCCCAAGCTATCAGTCAAGTCACCAAAGACCAAGAGGT
AGGTTCAGAGCATGTTCTCTTTGCCATTTTGCTTAATCCAGATATTATGGCGACTCGCTTATTAGAGATGGCGGGTTATA
CTATCAAGGATAAAGGAAATGGGGAGCCTCGCTTAGCTGATTTACGAAAAGCTATCGAGATTCATGCAGGCTATAGCAAA
GAAATAATTAAGGCTATCCACGAGTTGCGTAAGCCAAAGAAAACCAAAAATCAAGGTTCTTTTTCAGACATGATGAAGCC
ACCAAGCACGGCTGGGGACTTGGCGGACTTTACACGTGATTTGACCGAGATGGCAAGCCAAGGTCTCTTAGAGCCAGTTA
TTGGCCGTGATGCTGAAGTATCACGGATGATTCAAGTGCTTAGTCGTAAAACCAAGAATAACCCTGTTCTGGTGGGTGAT
GCAGGTGTGGGTAAAACGGCCCTAGCCTACGGCCTAGCCCAACGCATTGCTAATGGTGCTATTCCTTATGAACTGCAAGA
CATGCGTGTTCTAGAGTTAGACATGATGAGTGTTGTTGCGGGGACCCGTTTTCGTGGGGATTTTGAAGAGCGCATGAATC
AAATCATTGACGATATTGAGTCAGATGGTAAGATTATTCTCTTTGTAGATGAATTGCATACCATTATGGGATCAGGAAGT
GGCATTGATAGCACGCTTGATGCTGCTAATATTTTAAAACCAGCCTTATCTCGTGGAACCCTCCATATGGTGGGTGCAAC
AACGCAGGAAGAATACCAAAAACACATTGAAAAAGATGCCGCTCTTTCGCGTCGCTTTGCTAAGATTTTAATTGAAGAAC
CTAATGTAGAAGATGCTTATCAGATTCTGCTAGGACTAAAAGGCTCTTACGAGACTTACCATAATGTGACCATTGCTGAT
CAGGCTGTTAGAACTGCTGTGAAAATGGCACATCGCTATCTGACCAGCAAAAACCTTCCGGATTCTGCCATTGATTTGTT
GGATGAAGCCAGTGCTACAGTGCAAGGTATGGTTAAAAAATCTAGTCCAGAAATCATCACGCCATTAGATCAAGCTTTGA
TTGATGGCGATATGAAGAAGGCCTCTCGTTTGTTGGCAAAAGACGTTAAAGGGCAACATCGCAAGCCAACAGCTGTGACA
GAAGAGGACATCCTGACGACCTTGAGCAAGCTATCAGGTATTCCACTGGAAAAACTCAGCCAAGCTGATAGCAAAAAATA
CCTTAATTTGGAAAAAGAACTGCATAAGCGCGTGATTGGGCAAGAAGATGCTGTCTCAGCTATTTCTAGAGCCATTCGCC
GTAATCAGTCAGGCATTCGTACAGGTAAACGTCCAATCGGTTCTTTCATGTTCCTTGGTCCAACAGGGGTTGGTAAGACC
GAGTTGGCAAAAGCCTTGGCAGAAGTTCTCTTTGATGACGCGTCCGCCCTTATCCGCTTTGATATGTCAGAGTATATGGA
GAAATTTGCGGCTTCTCGCCTTAATGGCGCACCTCCAGGCTATGTTGGTTACGATGAAGGTGGTGAATTAACAGAGAAGG
TCAGAAACAAGCCTTATTCTGTGCTCCTCTTTGACGAGGTGGAAAAAGCTCACCCTGATATTTTCAACGTCCTCTTACAA
GTGCTTGATGATGGCATGTTGACAGATAGCCGTGGGCGTAAAGTGGACTTCTCAAATACCATTATTATCATGACAAGTAA
TCTAGGGGCAACAGCTCTGCGTGATGATAAAACAGTTGGCTTTGGGGCAAAAGGCATTAGCCATGACCACCAAGCCATGG
AAAAACGGATTTTGGAAGAGTTGAAGAAAGCTTACCGACCAGAATTTATCAACCGAATTGATGAAAAGGTTGTCTTCCAC
AGCCTCACTCAGGACAATATGAGAGAAGTGGTCAAGATTATGGTGCAACCGTTGATCGCTACTTTGGCAGAAAAAGGCAT
TACCCTCAAATTCCAGCCAATGGCCCTCAAGTATTTATCAGAAGAAGGGTATGATGTGGAAATGGGTGCTCGTCCATTGC
GCCGCACTTTGCAAACTCAGGTGGAAGATAAATTGTCTGAATTGATTCTTGCTGGTGAATTGGCAAGTGGTCATACCCTG
AAAATTGGCCTTTCTCATGGAAAACTCAGCTTTAACATTGAGTGA

Domains

Predicted by InterproScan.

• ATPase family associated with various cellular activities (AAA) (AAA) (236-368)

• AAA lid domain (AAA_lid_9) (376-462)

• AAA domain (Cdc48 subfamily) (AAA_2) (544-715)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (15-53)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (95-137)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (722-801)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Streptococcus mutans UA159	76.876	99.877	0.768
clpC	Streptococcus thermophilus LMG 18311	73.162	100	0.733
clpC	Streptococcus thermophilus LMD-9	73.162	100	0.733
clpC	Streptococcus pneumoniae TIGR4	67.282	99.877	0.672
clpC	Streptococcus pneumoniae Rx1	67.282	99.877	0.672
clpC	Streptococcus pneumoniae D39	67.282	99.877	0.672
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	48.921	100	0.501
clpC	Bacillus subtilis subsp. subtilis str. 168	42.96	100	0.439