Detailed information NTG1127751

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: FGL14_RS08020
• Genome accession: NZ_LR594045
• Coordinates: 1569360..1570397 (-)
• Length: 345 a.a.
• NCBI ID: WP_015017242.1
• Uniprot ID: A0A9X8T209
• Organism: Streptococcus dysgalactiae subsp. equisimilis strain NCTC9413
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1564360..1575397

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FGL14_RS07995 (NCTC9413_01659)	-	1565645..1566423 (-)	779	Protein_1504	substrate-binding domain-containing protein	-
FGL14_RS08000 (NCTC9413_01660)	-	1566423..1566803 (-)	381	Protein_1505	ATP-binding cassette domain-containing protein	-
FGL14_RS08005 (NCTC9413_01661)	rbsD	1566819..1567217 (-)	399	WP_003051896.1	D-ribose pyranase	-
FGL14_RS08010 (NCTC9413_01662)	rbsK	1567192..1568103 (-)	912	WP_003061715.1	ribokinase	-
FGL14_RS08015 (NCTC9413_01663)	-	1568096..1569079 (-)	984	WP_003053684.1	LacI family DNA-binding transcriptional regulator	-
FGL14_RS08020 (NCTC9413_01664)	sepM	1569360..1570397 (-)	1038	WP_015017242.1	SepM family pheromone-processing serine protease	Regulator
FGL14_RS08025 (NCTC9413_01665)	coaD	1570384..1570875 (-)	492	WP_065957290.1	pantetheine-phosphate adenylyltransferase	-
FGL14_RS08030 (NCTC9413_01666)	rsmD	1570865..1571404 (-)	540	WP_014612463.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
FGL14_RS08035 (NCTC9413_01667)	asnA	1571680..1572672 (-)	993	WP_003061055.1	aspartate--ammonia ligase	-
FGL14_RS08040 (NCTC9413_01668)	arcC	1572999..1573949 (-)	951	WP_012767309.1	carbamate kinase	-

Sequence

Protein

• Length: 345 a.a.
• Molecular weight: 37603.18 Da
• Isoelectric Point: 9.4270

>NTDB_id=1127751 FGL14_RS08020 WP_015017242.1 1569360..1570397(-) (sepM) [Streptococcus dysgalactiae subsp. equisimilis strain NCTC9413]
MKTIKKIKWWLISLIALVALLIVLFFPLPYYVEMPGGAYDIRSVVKVNGKEDKDKGSYQFVAVSLSRASLAQLLYAWLTP
FTEISSVEDTTGGYSDADYIRINQFYMETSQNAAVYQALTLADKPVTLDYKGVYVLDISKDSTFKGTLNLADTVTGVNHK
QFTSSTELVDYVSHLKLGDKVTVQFISNSEPKSETGRIIKLKNGKNGIGIALTDHTKVNSAEKIEFSTQGVGGPSAGLMF
TLDIYDQINKEDLRKGRHIAGTGTIGKDGEVGDIGGAGLKVVAAADAGAEIFFVPNNPVDKAVKKANPKAISNYEEAKRA
AKQLKTKMKIVPVTTVQDALAYLRQ

Nucleotide

• Length: 1038 bp

>NTDB_id=1127751 FGL14_RS08020 WP_015017242.1 1569360..1570397(-) (sepM) [Streptococcus dysgalactiae subsp. equisimilis strain NCTC9413]
ATGAAAACAATTAAAAAAATTAAATGGTGGCTGATTAGCCTAATTGCCCTCGTGGCTCTGCTTATCGTCCTTTTTTTCCC
TCTTCCTTATTATGTTGAAATGCCTGGCGGAGCCTATGACATTCGATCTGTGGTCAAGGTTAATGGCAAAGAAGATAAAG
ATAAAGGCTCCTATCAGTTTGTGGCAGTCAGTCTCAGTCGAGCCAGTTTAGCTCAGTTGCTCTATGCTTGGCTAACCCCT
TTTACTGAAATCAGTTCAGTTGAGGATACCACAGGCGGTTATAGCGATGCAGACTATATCCGCATTAATCAATTCTACAT
GGAAACCTCACAAAATGCTGCGGTCTATCAGGCATTGACCTTGGCAGACAAACCAGTTACTTTGGACTACAAAGGGGTAT
ATGTGTTAGATATTAGCAAGGATTCAACCTTTAAAGGTACTTTAAACTTAGCAGATACGGTAACGGGAGTGAATCACAAA
CAATTTACGAGTTCAACAGAACTTGTGGACTATGTCTCTCATTTAAAACTTGGTGATAAGGTGACTGTGCAGTTTATTAG
TAATAGCGAACCTAAGTCTGAAACAGGTCGTATCATCAAACTAAAAAATGGTAAAAATGGTATCGGCATTGCTTTAACAG
ACCATACTAAAGTCAATTCAGCAGAGAAAATCGAGTTTAGTACCCAAGGTGTTGGGGGTCCTAGCGCAGGCTTAATGTTT
ACATTAGATATCTACGACCAAATTAATAAAGAAGACCTTCGTAAAGGAAGACATATCGCCGGGACAGGAACCATTGGTAA
AGATGGTGAAGTTGGAGATATTGGCGGTGCGGGTCTTAAGGTCGTTGCTGCTGCAGATGCTGGTGCTGAGATTTTCTTTG
TGCCGAATAATCCTGTGGATAAAGCTGTTAAAAAAGCCAATCCAAAAGCTATTAGCAATTATGAAGAGGCCAAGCGAGCA
GCCAAGCAGTTAAAAACAAAAATGAAAATTGTTCCTGTAACAACTGTTCAGGATGCCCTAGCCTACCTTCGTCAATAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (130-192)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (233-299)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	71.594	100	0.716