Detailed information NTG1127643

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: FGL16_RS08315
• Genome accession: NZ_LR594043
• Coordinates: 1561902..1562951 (-)
• Length: 349 a.a.
• NCBI ID: WP_014736227.1
• Uniprot ID: A0A0Z8PJI1
• Organism: Streptococcus suis strain NCTC10237
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1556902..1567951

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FGL16_RS08290 (NCTC10237_01628)	nadE	1557569..1558393 (+)	825	WP_014736225.1	ammonia-dependent NAD(+) synthetase	-
FGL16_RS08300 (NCTC10237_01630)	-	1559428..1559955 (-)	528	WP_002942846.1	VanZ family protein	-
FGL16_RS08305 (NCTC10237_01631)	rlmN	1559952..1561064 (-)	1113	WP_014736226.1	23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN	-
FGL16_RS08310 (NCTC10237_01632)	-	1561073..1561714 (-)	642	WP_014638483.1	YutD-like domain-containing protein	-
FGL16_RS08315 (NCTC10237_01633)	sepM	1561902..1562951 (-)	1050	WP_014736227.1	SepM family pheromone-processing serine protease	Regulator
FGL16_RS08320 (NCTC10237_01634)	coaD	1562938..1563426 (-)	489	WP_014736228.1	pantetheine-phosphate adenylyltransferase	-
FGL16_RS08325 (NCTC10237_01635)	rsmD	1563416..1563955 (-)	540	WP_014638485.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
FGL16_RS08330 (NCTC10237_01636)	-	1564264..1564986 (-)	723	WP_014736229.1	hypothetical protein	-
FGL16_RS08335 (NCTC10237_01637)	-	1565043..1565429 (-)	387	WP_004194735.1	rhodanese-like domain-containing protein	-
FGL16_RS08340 (NCTC10237_01638)	-	1565429..1565647 (-)	219	WP_032512480.1	YqgQ family protein	-
FGL16_RS08345 (NCTC10237_01639)	-	1565931..1566479 (-)	549	WP_014736231.1	response regulator transcription factor	-
FGL16_RS08350 (NCTC10237_01640)	-	1566476..1567570 (-)	1095	WP_014736232.1	histidine kinase	-

Sequence

Protein

• Length: 349 a.a.
• Molecular weight: 37775.85 Da
• Isoelectric Point: 4.6112

>NTDB_id=1127643 FGL16_RS08315 WP_014736227.1 1561902..1562951(-) (sepM) [Streptococcus suis strain NCTC10237]
MKKNRKLTLIASIVLGTLLIWFAVFVRLPYYLESPGGAADIRQVLTVNNQIDQEDGSYNFTYVSVQQATALQLFAAQFDP
YTTVRSSEEMTGGADNEEYFRIARFYMETSQNMAKYQGLTLAGKEVNLDFFGVYVLALTDDSTFKKVLNIADTVVSINGK
TFESSPDLIKYVSGLELGSDVTVGYISAGQEKSADGKIIKLSNGKNGIGITLVDHTEVQSSIPIDFQTGDIGGPSAGLMF
TLAIYTQLAEPDLRDGRIIAGTGTIEQDGKVGDIGGADKKVISAAKSGASIFFVPNNPVDVEVLKKNPKAKTNYEEAKEA
AEKAGLDIEVVPVKTVQEAIDYLKKTKGE

Nucleotide

• Length: 1050 bp

>NTDB_id=1127643 FGL16_RS08315 WP_014736227.1 1561902..1562951(-) (sepM) [Streptococcus suis strain NCTC10237]
ATGAAGAAAAATAGGAAGTTAACCTTAATTGCATCTATTGTTTTAGGAACTCTTTTGATTTGGTTTGCCGTTTTTGTTCG
TCTGCCTTATTATTTGGAAAGTCCAGGTGGAGCTGCCGATATTCGTCAGGTACTAACGGTGAACAATCAAATAGACCAAG
AGGATGGCTCTTACAACTTCACCTATGTATCAGTCCAACAAGCTACAGCTTTACAACTATTCGCTGCTCAGTTTGATCCC
TATACGACAGTTCGTTCCTCTGAAGAGATGACAGGAGGGGCCGACAATGAGGAGTATTTCCGTATAGCACGGTTTTACAT
GGAAACTTCGCAAAATATGGCGAAGTATCAAGGATTGACCTTGGCAGGAAAAGAAGTCAATCTTGATTTCTTTGGTGTCT
ATGTGCTTGCCTTGACGGATGATTCAACCTTTAAAAAAGTTCTTAATATTGCCGACACTGTTGTGAGTATCAATGGAAAA
ACATTTGAGTCTTCTCCTGATTTGATTAAATATGTGAGTGGCTTGGAACTTGGAAGTGATGTAACAGTTGGTTATATTAG
CGCTGGTCAGGAAAAATCTGCGGACGGTAAGATTATCAAATTGTCTAATGGCAAAAACGGGATAGGTATCACTCTCGTAG
ATCATACAGAGGTTCAAAGTTCGATTCCGATTGATTTCCAAACAGGAGATATTGGTGGTCCAAGTGCTGGTCTGATGTTT
ACACTTGCCATCTATACTCAACTCGCAGAGCCTGACTTACGTGATGGTCGGATTATTGCTGGTACGGGGACTATCGAGCA
GGATGGAAAAGTAGGTGACATTGGTGGGGCTGATAAGAAGGTCATTTCGGCAGCTAAGTCTGGTGCAAGTATCTTTTTTG
TACCAAACAATCCAGTTGATGTAGAAGTTTTGAAGAAAAACCCAAAGGCTAAAACGAACTATGAAGAAGCTAAGGAAGCA
GCCGAGAAAGCAGGTCTAGATATTGAGGTAGTTCCTGTGAAAACTGTTCAAGAGGCTATTGATTATTTGAAGAAAACAAA
GGGCGAGTAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (132-195)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (232-315)

3D structure

• AlphaFold DB: A0A0Z8PJI1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	61.095	99.427	0.607