Detailed information NTG1127320

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: FGL04_RS10165
• Genome accession: NZ_LR594035
• Coordinates: 1965860..1968301 (-)
• Length: 813 a.a.
• NCBI ID: WP_138069069.1
• Uniprot ID: A0A4U9ZRJ7
• Organism: Streptococcus pseudoporcinus strain NCTC5385
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 1960860..1973301

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FGL04_RS10155 (NCTC5385_02198)	groL	1963689..1965317 (-)	1629	WP_007893807.1	chaperonin GroEL	-
FGL04_RS10160 (NCTC5385_02199)	groES	1965357..1965647 (-)	291	WP_138069068.1	co-chaperone GroES	-
FGL04_RS10165 (NCTC5385_02200)	clpC	1965860..1968301 (-)	2442	WP_138069069.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
FGL04_RS10170 (NCTC5385_02201)	-	1968301..1968762 (-)	462	WP_138069070.1	CtsR family transcriptional regulator	-
FGL04_RS10175	-	1968935..1969138 (-)	204	WP_003085753.1	cold-shock protein	-
FGL04_RS10180 (NCTC5385_02203)	-	1969488..1969757 (+)	270	WP_007893877.1	hypothetical protein	-
FGL04_RS10185 (NCTC5385_02205)	-	1969760..1971834 (+)	2075	Protein_1985	cation:proton antiporter	-
FGL04_RS10190 (NCTC5385_02206)	-	1971958..1972920 (+)	963	WP_138069071.1	VOC family protein	-

Sequence

Protein

• Length: 813 a.a.
• Molecular weight: 90495.03 Da
• Isoelectric Point: 5.9118

>NTDB_id=1127320 FGL04_RS10165 WP_138069069.1 1965860..1968301(-) (clpC) [Streptococcus pseudoporcinus strain NCTC5385]
MIDYSLKMQEIFKQAQYQAARFDSQYLETWHLLLAMVVVNNSLAGLVFNEFDAKVTMEEYEAAAILAMGQTPNDDVKEWT
LKGQSRTLTKILQFSDAIRQVTGAQEVGSEHVLFALLLNPDVMATRLLEMAGFKLRDEGQGDLKISDLRKAIERQAAYSK
ETIKAIYELRKPKKTKAGGTFSDMMKPPSSAGDLSDFTRDLTQMASQGLLEPVIGREKEITRMVQVLSRKTKNNPVLVGD
AGVGKTALAYGLAQRIVEGAIPYELQDMRVLELDMMSVVAGTRFRGDFEERMNQIIDDIEADGKIILFVDELHTIMGSGS
GIDSTLDAANILKPTLSRGTLHMVGATTQEEYQKHIEKDAALSRRFAKILIEEPNLEDAYQILLGLKSSYEMYHNVRISD
QAVKVAVKVAHRYLTSKNLPDSAIDLLDEASATVQGLIKKETPSFLSPIDQAILDGNFKEVTSILKANKKTKPSPTPVTE
DDIMATLSRLSGIPLEKISQADSQKYLQLEKELHKRVIGQDEAISAISRAIRRNQSGIRTGKRPIGSFMFLGPTGVGKTE
LAKALAEVLFDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYDEGGELTEKVRNKPYSVLLFDEVEKAHPDIFNVLLQV
LDDGVLTDSRGRKVDFTNTIIIMTSNLGATALRDDKTVGFGARDVSQDHQAMEKRILEELKKAYRPEFINRIDEKVVFHS
LSQEDMQQVVRIMVKPLIAALEEKGITLKFQPSALKYLSEKGYDLEMGARPLRRTIQTEVEDKLSELLLSGQLGSGHKLK
IGLAKGKIKCDIE

Nucleotide

• Length: 2442 bp

>NTDB_id=1127320 FGL04_RS10165 WP_138069069.1 1965860..1968301(-) (clpC) [Streptococcus pseudoporcinus strain NCTC5385]
ATGATAGATTATTCACTAAAAATGCAGGAAATTTTCAAGCAGGCTCAATATCAGGCAGCTCGCTTTGATAGCCAATATTT
AGAAACATGGCATCTTCTTTTAGCGATGGTTGTGGTTAACAACTCACTAGCTGGACTTGTTTTCAATGAATTTGACGCTA
AAGTTACTATGGAAGAATATGAAGCGGCAGCTATTTTAGCTATGGGACAAACGCCAAATGATGATGTGAAAGAGTGGACC
TTGAAGGGTCAATCTAGAACCTTAACAAAAATTCTCCAATTTTCAGATGCTATCCGTCAGGTAACAGGTGCTCAGGAAGT
GGGGTCAGAACACGTCCTTTTTGCCCTATTGTTAAATCCTGATGTTATGGCAACTCGCTTACTAGAAATGGCTGGTTTTA
AACTACGTGATGAGGGTCAAGGAGATTTGAAAATCTCTGATTTACGTAAAGCAATTGAGAGGCAAGCTGCTTATAGTAAA
GAGACCATTAAGGCTATTTATGAATTGCGCAAACCTAAAAAAACAAAAGCAGGTGGGACATTCTCAGATATGATGAAACC
GCCAAGTTCAGCAGGTGACCTCTCTGATTTCACGCGTGATTTAACACAAATGGCCAGTCAAGGCCTTTTGGAACCGGTGA
TTGGCCGTGAAAAAGAAATTACTCGAATGGTTCAGGTGCTAAGCCGTAAAACTAAGAATAATCCTGTCTTAGTCGGAGAC
GCGGGTGTTGGGAAAACAGCCTTGGCTTATGGTCTAGCTCAACGAATTGTCGAGGGAGCTATTCCTTACGAATTGCAGGA
TATGCGAGTTTTGGAACTAGACATGATGAGTGTGGTTGCAGGAACTCGTTTTCGGGGTGATTTTGAAGAACGAATGAACC
AAATCATAGATGATATTGAAGCAGATGGGAAAATTATTCTGTTTGTTGATGAATTACATACGATTATGGGTTCTGGAAGT
GGTATTGATAGTACTTTAGATGCGGCTAATATTTTAAAACCAACTTTGTCTCGTGGGACACTACATATGGTAGGTGCGAC
AACTCAGGAAGAATACCAAAAACATATTGAAAAAGACGCAGCCTTATCTCGTCGCTTTGCTAAAATTTTAATTGAAGAAC
CAAATCTTGAAGATGCCTACCAAATCCTACTTGGACTAAAATCTTCTTATGAAATGTATCATAATGTTAGAATTTCAGAC
CAAGCTGTTAAAGTGGCAGTTAAGGTTGCACACCGTTATTTAACAAGTAAAAATTTGCCAGATTCAGCAATAGACCTCTT
AGATGAAGCCAGTGCAACGGTCCAAGGGCTCATAAAAAAAGAGACACCCTCCTTTTTAAGTCCTATAGACCAGGCTATCC
TCGATGGCAATTTTAAAGAAGTGACTAGCATATTAAAAGCTAATAAGAAAACGAAGCCTAGCCCAACCCCGGTTACAGAA
GATGACATCATGGCAACTTTAAGTAGATTGTCGGGGATACCACTTGAGAAAATTAGCCAAGCTGATAGTCAAAAATACCT
CCAATTAGAGAAAGAATTACACAAACGGGTTATTGGTCAAGACGAAGCTATTTCAGCTATTTCAAGGGCTATTCGTCGCA
ATCAATCTGGTATCCGAACTGGTAAGCGTCCAATTGGCTCATTTATGTTTCTAGGTCCAACAGGTGTTGGAAAAACAGAG
CTTGCTAAAGCCTTGGCTGAGGTTTTATTTGATGATGAGTCAGCATTAATCCGTTTCGATATGTCAGAATACATGGAGAA
ATTTGCAGCCAGTCGTCTCAATGGTGCCCCTCCAGGATATGTAGGCTATGATGAAGGTGGTGAACTGACAGAAAAAGTAA
GGAATAAACCTTATTCTGTTTTGCTTTTTGATGAAGTTGAAAAAGCTCATCCAGATATTTTCAACGTACTTCTTCAAGTT
TTGGACGATGGGGTACTGACAGACTCTCGTGGTCGAAAAGTTGATTTTACAAATACTATTATTATCATGACCAGTAATTT
AGGTGCGACAGCACTTCGAGATGATAAAACTGTAGGATTTGGTGCTCGAGATGTTAGTCAAGATCACCAAGCTATGGAAA
AACGTATTTTAGAGGAGCTAAAGAAAGCTTATCGTCCTGAATTTATTAATCGTATTGATGAAAAGGTTGTTTTCCACAGC
CTAAGTCAAGAAGATATGCAACAAGTGGTGAGGATTATGGTGAAACCGTTGATTGCTGCCTTAGAAGAAAAAGGAATCAC
TCTCAAATTTCAACCGTCAGCACTTAAATACCTATCTGAGAAAGGCTATGATCTGGAGATGGGAGCTCGTCCACTTCGAA
GAACGATTCAAACAGAAGTTGAGGATAAATTGTCAGAATTACTTCTTTCAGGACAGTTAGGCTCTGGGCATAAATTAAAA
ATTGGTTTAGCCAAAGGCAAAATAAAATGTGACATAGAATAA

Domains

Predicted by InterproScan.

• ATPase family associated with various cellular activities (AAA) (AAA) (236-368)

• AAA domain (Cdc48 subfamily) (AAA_2) (543-714)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (721-800)

• AAA lid domain (AAA_lid_9) (376-453)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (18-51)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (101-134)

3D structure

• AlphaFold DB: A0A4U9ZRJ7

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Streptococcus mutans UA159	74.539	100	0.745
clpC	Streptococcus thermophilus LMD-9	72.482	100	0.726
clpC	Streptococcus thermophilus LMG 18311	72.482	100	0.726
clpC	Streptococcus pneumoniae TIGR4	65.437	100	0.654
clpC	Streptococcus pneumoniae Rx1	65.437	100	0.654
clpC	Streptococcus pneumoniae D39	65.437	100	0.654
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	48.024	100	0.493
clpC	Bacillus subtilis subsp. subtilis str. 168	44.765	100	0.458