Detailed information NTG1127312

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: FGL04_RS08000
• Genome accession: NZ_LR594035
• Coordinates: 1556672..1557715 (-)
• Length: 347 a.a.
• NCBI ID: WP_138068819.1
• Uniprot ID: A0A4U9Z5D8
• Organism: Streptococcus pseudoporcinus strain NCTC5385
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1551672..1562715

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FGL04_RS07975 (NCTC5385_01738)	-	1551744..1552688 (-)	945	WP_138068814.1	ABC transporter permease subunit	-
FGL04_RS07980 (NCTC5385_01739)	-	1552691..1554169 (-)	1479	WP_138068815.1	sugar ABC transporter ATP-binding protein	-
FGL04_RS07985 (NCTC5385_01740)	rbsD	1554185..1554583 (-)	399	WP_138068816.1	D-ribose pyranase	-
FGL04_RS07990 (NCTC5385_01741)	-	1554558..1555469 (-)	912	WP_138068817.1	ribokinase	-
FGL04_RS07995 (NCTC5385_01742)	-	1555462..1556445 (-)	984	WP_138068818.1	LacI family DNA-binding transcriptional regulator	-
FGL04_RS08000 (NCTC5385_01743)	sepM	1556672..1557715 (-)	1044	WP_138068819.1	SepM family pheromone-processing serine protease	Regulator
FGL04_RS08005 (NCTC5385_01744)	coaD	1557702..1558193 (-)	492	WP_138068820.1	pantetheine-phosphate adenylyltransferase	-
FGL04_RS08010 (NCTC5385_01745)	rsmD	1558183..1558722 (-)	540	WP_138068821.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
FGL04_RS08015 (NCTC5385_01746)	asnA	1558968..1559960 (-)	993	WP_138068822.1	aspartate--ammonia ligase	-
FGL04_RS08020 (NCTC5385_01747)	arcC	1560141..1561091 (-)	951	WP_138068823.1	carbamate kinase	-
FGL04_RS08025 (NCTC5385_01748)	-	1561108..1562439 (-)	1332	WP_138068824.1	dipeptidase	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 38335.32 Da
• Isoelectric Point: 10.1350

>NTDB_id=1127312 FGL04_RS08000 WP_138068819.1 1556672..1557715(-) (sepM) [Streptococcus pseudoporcinus strain NCTC5385]
MKIIKKVKWWLISILAVVALLFALFFPLPYYIEMPGGAYDIRSVLKVNDKRDKEKGSYNFVAVSLSRATFAQILYAWVTP
FTEISSLENTTGGYSAADYMRINQYYMETSQNGAIYQALQLAGKPVSLDYLGVYVLDVNKESTFRGILNIADTVTGVNQK
EFKSSTELIKYVSSLKRGETVTVQYTSGNEKKSKSGKVIKLKNGKNGIGIGLTDHTKVHTDEKIEFSTEGVGGPSAGLMF
TLDIYDQLNQENLRKGRRIAGTGTIDQDGKVGDIGGAGLKVVAAANEGADIFFVPNNPVDKRIKKVKPNAKTNYKEALEV
AKKIKTKMKIVPVRNVKEAIAYLQKTK

Nucleotide

• Length: 1044 bp

>NTDB_id=1127312 FGL04_RS08000 WP_138068819.1 1556672..1557715(-) (sepM) [Streptococcus pseudoporcinus strain NCTC5385]
ATGAAGATAATTAAAAAAGTCAAATGGTGGTTAATTAGTATTCTGGCAGTAGTTGCCCTCTTGTTTGCCCTCTTTTTCCC
TTTACCTTATTATATTGAGATGCCTGGTGGAGCCTACGATATCCGTTCAGTGCTTAAGGTAAACGATAAAAGGGATAAGG
AGAAAGGCTCTTATAATTTTGTGGCGGTCAGTTTGAGTCGAGCCACTTTTGCTCAAATTCTTTATGCTTGGGTAACGCCA
TTCACAGAGATTTCATCTTTGGAAAATACAACTGGGGGCTATAGTGCGGCAGATTATATGCGCATCAATCAATATTACAT
GGAGACCTCTCAAAACGGAGCTATCTATCAAGCCTTACAATTAGCTGGGAAACCTGTTTCTTTAGACTACCTAGGTGTTT
ATGTTTTGGATGTCAATAAAGAGTCTACTTTTCGTGGTATTCTAAATATTGCTGATACTGTTACAGGGGTCAATCAAAAA
GAATTTAAGAGTTCAACTGAACTTATTAAATACGTTTCAAGTTTGAAACGGGGTGAAACAGTGACGGTGCAATATACCAG
CGGTAATGAGAAAAAATCTAAAAGTGGTAAGGTTATTAAGCTAAAAAATGGGAAGAATGGTATTGGGATTGGCTTAACGG
ACCACACAAAAGTCCATACAGATGAAAAGATTGAGTTTTCGACAGAAGGTGTAGGTGGACCAAGTGCTGGGCTTATGTTT
ACACTGGATATTTATGATCAACTAAATCAAGAAAACCTGCGTAAAGGTCGTCGTATTGCTGGTACTGGAACGATTGATCA
AGATGGCAAAGTTGGTGATATTGGTGGTGCAGGATTAAAAGTTGTTGCTGCGGCTAACGAAGGAGCTGATATTTTCTTTG
TACCCAACAATCCAGTTGATAAACGGATCAAAAAAGTAAAACCAAATGCAAAGACCAATTATAAAGAAGCCTTAGAAGTT
GCTAAAAAAATAAAAACCAAGATGAAAATTGTTCCCGTTAGAAATGTCAAAGAAGCTATTGCTTACTTGCAAAAGACAAA
ATAA

Domains

Predicted by InterproScan.

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (232-340)

• PDZ domain (PDZ_2) (131-192)

3D structure

• AlphaFold DB: A0A4U9Z5D8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	72.174	99.424	0.718