Detailed information NTG1127253

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: FGL00_RS08055
• Genome accession: NZ_LR594034
• Coordinates: 1597728..1598765 (-)
• Length: 345 a.a.
• NCBI ID: WP_015017242.1
• Uniprot ID: A0A9X8T209
• Organism: Streptococcus dysgalactiae subsp. equisimilis strain NCTC8546
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1592728..1603765

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FGL00_RS08030 (NCTC8546_01669)	-	1594013..1594791 (-)	779	Protein_1530	substrate-binding domain-containing protein	-
FGL00_RS08035 (NCTC8546_01670)	-	1594791..1595171 (-)	381	Protein_1531	ATP-binding cassette domain-containing protein	-
FGL00_RS08040 (NCTC8546_01671)	rbsD	1595187..1595585 (-)	399	WP_003051896.1	D-ribose pyranase	-
FGL00_RS08045 (NCTC8546_01672)	rbsK	1595560..1596471 (-)	912	WP_003061715.1	ribokinase	-
FGL00_RS08050 (NCTC8546_01673)	-	1596464..1597447 (-)	984	WP_003053684.1	LacI family DNA-binding transcriptional regulator	-
FGL00_RS08055 (NCTC8546_01674)	sepM	1597728..1598765 (-)	1038	WP_015017242.1	SepM family pheromone-processing serine protease	Regulator
FGL00_RS08060 (NCTC8546_01675)	coaD	1598752..1599243 (-)	492	WP_065957290.1	pantetheine-phosphate adenylyltransferase	-
FGL00_RS08065 (NCTC8546_01676)	rsmD	1599233..1599772 (-)	540	WP_014612463.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
FGL00_RS08070 (NCTC8546_01677)	asnA	1600007..1600999 (-)	993	WP_003061055.1	aspartate--ammonia ligase	-
FGL00_RS08075 (NCTC8546_01678)	arcC	1601326..1602276 (-)	951	WP_012767309.1	carbamate kinase	-

Sequence

Protein

• Length: 345 a.a.
• Molecular weight: 37603.18 Da
• Isoelectric Point: 9.4270

>NTDB_id=1127253 FGL00_RS08055 WP_015017242.1 1597728..1598765(-) (sepM) [Streptococcus dysgalactiae subsp. equisimilis strain NCTC8546]
MKTIKKIKWWLISLIALVALLIVLFFPLPYYVEMPGGAYDIRSVVKVNGKEDKDKGSYQFVAVSLSRASLAQLLYAWLTP
FTEISSVEDTTGGYSDADYIRINQFYMETSQNAAVYQALTLADKPVTLDYKGVYVLDISKDSTFKGTLNLADTVTGVNHK
QFTSSTELVDYVSHLKLGDKVTVQFISNSEPKSETGRIIKLKNGKNGIGIALTDHTKVNSAEKIEFSTQGVGGPSAGLMF
TLDIYDQINKEDLRKGRHIAGTGTIGKDGEVGDIGGAGLKVVAAADAGAEIFFVPNNPVDKAVKKANPKAISNYEEAKRA
AKQLKTKMKIVPVTTVQDALAYLRQ

Nucleotide

• Length: 1038 bp

>NTDB_id=1127253 FGL00_RS08055 WP_015017242.1 1597728..1598765(-) (sepM) [Streptococcus dysgalactiae subsp. equisimilis strain NCTC8546]
ATGAAAACAATTAAAAAAATTAAATGGTGGCTGATTAGCCTAATTGCCCTCGTGGCTCTGCTTATCGTCCTTTTTTTCCC
TCTTCCTTATTATGTTGAAATGCCTGGCGGAGCCTATGACATTCGATCTGTGGTCAAGGTTAATGGCAAAGAAGATAAAG
ATAAAGGCTCCTATCAGTTTGTGGCAGTCAGTCTCAGTCGAGCCAGTTTAGCTCAGTTGCTCTATGCTTGGCTAACCCCT
TTTACTGAAATCAGTTCAGTTGAGGATACCACAGGCGGTTATAGCGATGCAGACTATATCCGCATTAATCAATTCTACAT
GGAAACCTCACAAAATGCTGCGGTCTATCAGGCATTGACCTTGGCAGACAAACCAGTTACTTTGGACTACAAAGGGGTAT
ATGTGTTAGATATTAGCAAGGATTCAACCTTTAAAGGTACTTTAAACTTAGCAGATACGGTAACGGGAGTGAATCACAAA
CAATTTACGAGTTCAACAGAACTTGTGGACTATGTCTCTCATTTAAAACTTGGTGATAAGGTGACTGTGCAGTTTATTAG
TAATAGCGAACCTAAGTCTGAAACAGGTCGTATCATCAAACTAAAAAATGGTAAAAATGGTATCGGCATTGCTTTAACAG
ACCATACTAAAGTCAATTCAGCAGAGAAAATCGAGTTTAGTACCCAAGGTGTTGGGGGTCCTAGCGCAGGCTTAATGTTT
ACATTAGATATCTACGACCAAATTAATAAAGAAGACCTTCGTAAAGGAAGACATATCGCCGGGACAGGAACCATTGGTAA
AGATGGTGAAGTTGGAGATATTGGCGGTGCGGGTCTTAAGGTCGTTGCTGCTGCAGATGCTGGTGCTGAGATTTTCTTTG
TGCCGAATAATCCTGTGGATAAAGCTGTTAAAAAAGCCAATCCAAAAGCTATTAGCAATTATGAAGAGGCCAAGCGAGCA
GCCAAGCAGTTAAAAACAAAAATGAAAATTGTTCCTGTAACAACTGTTCAGGATGCCCTAGCCTACCTTCGTCAATAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (130-192)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (233-299)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	71.594	100	0.716