Detailed information NTG1127171

Bioinformatically predicted

Overview

• Name: clpE
• Type: Regulator
• Locus tag: FGK99_RS02870
• Genome accession: NZ_LR594033
• Coordinates: 600784..603039 (-)
• Length: 751 a.a.
• NCBI ID: WP_115267039.1
• Uniprot ID: -
• Organism: Streptococcus equi subsp. zooepidemicus strain NCTC4675
• Function: repress competence development (at the early growth phase) (predicted from homology) Competence regulation

Genomic Context

Location: 595784..608039

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FGK99_RS02855 (NCTC4675_00583)	ileS	596370..599168 (+)	2799	WP_138118945.1	isoleucine--tRNA ligase	-
FGK99_RS02860 (NCTC4675_00584)	-	599827..600129 (-)	303	WP_012515246.1	DUF1827 family protein	-
FGK99_RS02865 (NCTC4675_00585)	-	600191..600637 (-)	447	WP_043040277.1	NUDIX hydrolase	-
FGK99_RS02870 (NCTC4675_00586)	clpE	600784..603039 (-)	2256	WP_115267039.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
FGK99_RS02875 (NCTC4675_00587)	-	603322..603552 (+)	231	WP_012515249.1	DUF1797 family protein	-
FGK99_RS02880 (NCTC4675_00588)	-	603995..605302 (-)	1308	WP_138118947.1	LPXTG cell wall anchor domain-containing protein	-
FGK99_RS02885 (NCTC4675_00589)	-	605655..606338 (+)	684	WP_111692289.1	amino acid ABC transporter permease	-
FGK99_RS02890 (NCTC4675_00590)	-	606340..607077 (+)	738	WP_138118949.1	amino acid ABC transporter ATP-binding protein	-

Sequence

Protein

• Length: 751 a.a.
• Molecular weight: 83922.32 Da
• Isoelectric Point: 5.7427

>NTDB_id=1127171 FGK99_RS02870 WP_115267039.1 600784..603039(-) (clpE) [Streptococcus equi subsp. zooepidemicus strain NCTC4675]
MLCQNCNLNESTIHLYTSINGKQRQIDLCQNCYQIMKTDPKNPILGGYTGNQKAQQQSQNPFFDDFFGDLNNFRAFGQLP
NTPPTQSGGQHGGGHNGGYRPNHTQPAQETNKGLLEEFGINITEMAKRGDIDPVIGRDDEIIRVIEILNRRTKNNPVLIG
EPGVGKTAVVEGLAQKIVDGDVPQKLQSKQVIRLDVVSLVQGTGIRGQFEERMQKLMEEIRKRHDVILFIDEIHEIVGAG
AVGDGSMDAGNILKPALARGELQLVGATTLNEYRIIEKDAALERRMQPVKVDEPSVEETITILKGIQPKYEDYHHVKYSQ
SAIEAAANLSNRYIQDRFLPDKAIDLLDEAGSKMNLTLNFVDPKDIDKRLIEAENLKTQATRDEDYERAAYFRDQIAKYK
EMQAQKLDEQDIPIITDKTIEAIVEQKTNIPVGDLKEKEQSQLVNLAADLKKHVIGQDDAVDKIAKAIRRNRVGLGAPNR
PIGSFLFVGPTGVGKTELSKQLAIELFGSADNMIRFDMSEYMEKHAVAKLVGAPPGYVGYEEAGQLTEQVRRNPYSLILL
DEIEKAHPDVMHMFLQVLDDGRLTDGQGRTVSFKDTIIIMTSNAGTGKTEASVGFGAAREGRTNSVLGELSHFFSPEFMN
RFDGIIEFQPLSKDNLLHIVHLMLDDVNHRLAHNNIHLDVTQKVKEKLVELGYDPKMGARPLRRTIQDYIEDAITDFYLE
HPAEKDLRAVLTSNGHIIIKPVVKSQAKQAD

Nucleotide

• Length: 2256 bp

>NTDB_id=1127171 FGK99_RS02870 WP_115267039.1 600784..603039(-) (clpE) [Streptococcus equi subsp. zooepidemicus strain NCTC4675]
ATGCTTTGTCAAAACTGTAATTTAAACGAATCAACTATTCATCTTTATACAAGTATTAACGGAAAGCAAAGACAGATTGA
TCTGTGCCAAAATTGCTACCAAATCATGAAAACAGACCCTAAAAATCCTATCCTGGGAGGCTATACTGGCAATCAAAAGG
CCCAGCAGCAGTCTCAAAACCCTTTCTTTGATGACTTTTTTGGTGACCTCAACAACTTTAGAGCCTTTGGTCAGCTCCCC
AATACACCACCTACCCAATCAGGAGGCCAGCATGGCGGAGGTCACAACGGTGGCTACCGTCCCAATCACACACAGCCAGC
ACAAGAGACTAACAAAGGTTTGCTTGAGGAATTCGGCATTAATATCACTGAAATGGCTAAGCGTGGTGATATTGATCCTG
TCATCGGACGTGACGATGAGATTATCCGCGTGATCGAGATTCTCAACCGTCGTACCAAAAATAACCCTGTCCTAATCGGA
GAACCAGGTGTTGGTAAGACTGCTGTCGTTGAAGGCCTTGCTCAAAAAATCGTTGATGGCGATGTGCCACAAAAGCTACA
GAGTAAGCAGGTGATTCGCCTTGATGTGGTTAGCCTCGTTCAGGGGACAGGTATTCGTGGCCAATTTGAAGAGCGCATGC
AAAAGCTCATGGAAGAAATCCGCAAGCGCCATGACGTGATTCTATTTATTGATGAAATCCATGAAATTGTGGGAGCTGGT
GCAGTTGGTGACGGCAGCATGGACGCAGGAAATATTTTAAAGCCAGCACTTGCTCGTGGTGAGCTTCAATTAGTGGGAGC
GACCACTCTCAATGAATACCGCATCATCGAAAAGGACGCAGCCCTTGAGCGACGCATGCAGCCGGTTAAGGTGGATGAGC
CCTCGGTTGAAGAAACAATCACTATCCTAAAAGGAATCCAACCCAAATATGAGGACTATCATCATGTCAAATATAGCCAG
TCAGCTATCGAAGCAGCTGCTAACCTCTCCAACCGCTATATTCAAGACCGCTTCTTGCCTGATAAGGCCATTGACCTGCT
AGATGAAGCCGGCTCAAAGATGAACCTAACCCTTAACTTTGTTGACCCCAAAGACATTGATAAGCGTTTGATTGAGGCTG
AAAACCTCAAGACACAAGCCACACGTGATGAGGATTATGAGCGAGCAGCCTATTTCCGCGATCAAATCGCCAAATATAAA
GAAATGCAGGCTCAAAAGCTAGATGAGCAGGATATTCCAATCATCACTGACAAGACCATCGAAGCAATCGTTGAGCAAAA
AACCAATATTCCAGTTGGTGATTTAAAGGAAAAGGAACAATCACAGCTAGTCAATCTGGCCGCCGATCTCAAAAAGCATG
TTATCGGTCAAGACGATGCTGTTGATAAAATTGCAAAAGCTATCCGTCGTAATCGTGTTGGACTGGGAGCCCCAAATCGT
CCTATCGGCTCCTTCCTCTTTGTTGGGCCGACTGGTGTCGGTAAAACAGAGCTTTCCAAGCAATTAGCCATTGAGCTTTT
TGGCTCTGCTGATAACATGATTCGCTTTGACATGTCTGAATACATGGAAAAGCACGCTGTGGCTAAGCTTGTCGGTGCCC
CTCCAGGCTACGTCGGCTACGAGGAAGCAGGTCAGCTAACAGAGCAGGTGCGCCGCAACCCTTATTCACTCATTCTTTTA
GATGAAATCGAAAAAGCCCACCCTGATGTCATGCACATGTTTTTACAGGTCCTAGATGACGGTCGATTGACTGATGGTCA
GGGACGAACCGTTAGCTTCAAGGACACTATTATCATCATGACGTCAAATGCTGGCACCGGCAAAACAGAAGCCTCAGTCG
GCTTTGGTGCTGCTAGAGAAGGACGGACAAACTCTGTCCTAGGTGAGCTTAGTCATTTCTTTAGTCCCGAATTTATGAAC
CGCTTTGACGGGATTATTGAGTTTCAGCCGCTAAGCAAGGACAATCTTTTACATATCGTTCATTTAATGCTCGATGATGT
TAACCACCGCCTTGCTCACAATAACATTCACCTTGATGTCACCCAAAAGGTCAAGGAAAAGCTCGTCGAGCTAGGCTATG
ATCCTAAGATGGGAGCACGACCATTGCGCCGCACCATTCAGGACTACATTGAGGATGCCATTACCGACTTCTACCTTGAG
CACCCAGCAGAAAAAGACCTGCGAGCTGTCCTGACCTCTAATGGACACATTATAATCAAGCCTGTAGTCAAATCTCAGGC
GAAGCAGGCGGACTAA

Domains

Predicted by InterproScan.

• AAA lid domain (AAA_lid_9) (295-392)

• AAA domain (Cdc48 subfamily) (AAA_2) (480-643)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (651-725)

• ATPase family associated with various cellular activities (AAA) (AAA) (157-270)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpE	Streptococcus mutans UA159	84.677	99.068	0.839
clpE	Streptococcus pneumoniae Rx1	82.47	100	0.827
clpE	Streptococcus pneumoniae D39	82.47	100	0.827
clpE	Streptococcus pneumoniae R6	82.47	100	0.827
clpE	Streptococcus pneumoniae TIGR4	82.337	100	0.826
clpC	Lactococcus lactis subsp. cremoris KW2	75.399	100	0.755
clpC	Bacillus subtilis subsp. subtilis str. 168	49.926	90.146	0.45
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	46.729	85.486	0.399
clpC	Streptococcus pneumoniae Rx1	47.903	82.557	0.395
clpC	Streptococcus pneumoniae D39	47.903	82.557	0.395
clpC	Streptococcus pneumoniae TIGR4	47.742	82.557	0.394
clpC	Streptococcus mutans UA159	47.343	82.69	0.391
clpC	Streptococcus thermophilus LMD-9	46.349	83.888	0.389
clpC	Streptococcus thermophilus LMG 18311	46.032	83.888	0.386