Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpC   Type   Regulator
Locus tag   FGK99_RS00830 Genome accession   NZ_LR594033
Coordinates   146993..149434 (+) Length   813 a.a.
NCBI ID   WP_138118665.1    Uniprot ID   -
Organism   Streptococcus equi subsp. zooepidemicus strain NCTC4675     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 141993..154434
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FGK99_RS00800 (NCTC4675_00162) rpsB 142184..142954 (-) 771 WP_012677249.1 30S ribosomal protein S2 -
  FGK99_RS00805 (NCTC4675_00163) ahpF 143414..144946 (-) 1533 WP_138118663.1 alkyl hydroperoxide reductase subunit F -
  FGK99_RS00810 (NCTC4675_00164) ahpC 144967..145527 (-) 561 WP_012514798.1 alkyl hydroperoxide reductase subunit C -
  FGK99_RS00820 - 146159..146362 (+) 204 WP_012514799.1 cold-shock protein -
  FGK99_RS00825 (NCTC4675_00167) - 146532..146993 (+) 462 WP_012677252.1 CtsR family transcriptional regulator -
  FGK99_RS00830 (NCTC4675_00168) clpC 146993..149434 (+) 2442 WP_138118665.1 ATP-dependent Clp protease ATP-binding subunit Regulator
  FGK99_RS00835 - 149784..149930 (-) 147 WP_080312399.1 putative holin-like toxin -
  FGK99_RS00840 (NCTC4675_00171) - 150210..150641 (+) 432 WP_138118667.1 hypothetical protein -
  FGK99_RS00845 (NCTC4675_00173) - 150862..151293 (+) 432 WP_014622158.1 hypothetical protein -
  FGK99_RS00850 (NCTC4675_00174) - 151295..152584 (+) 1290 WP_138118669.1 lipase family protein -
  FGK99_RS00855 (NCTC4675_00175) - 152566..152958 (+) 393 WP_111710688.1 hypothetical protein -
  FGK99_RS00860 (NCTC4675_00176) - 152939..153229 (+) 291 WP_138118671.1 hypothetical protein -
  FGK99_RS00865 (NCTC4675_00177) groES 153529..153816 (+) 288 WP_012514806.1 co-chaperone GroES -

Sequence

Protein


Download         Length: 813 a.a.        Molecular weight: 90410.21 Da        Isoelectric Point: 6.3498

>NTDB_id=1127161 FGK99_RS00830 WP_138118665.1 146993..149434(+) (clpC) [Streptococcus equi subsp. zooepidemicus strain NCTC4675]
MMIYSLKMQDIFNQAQFQAERFDSPYLETWHILLAMVAVDHSLAAMVLSEFERKIRAEEYEAAAILAMGKSPKEVTSVQF
KPQSKALSEILAFAHAICQVTNEHEVGSEHVLFAILLNPDIMASRLLELAGYRLKDSGKGEPRFADLRKAIELNAGYSKE
TIKAIHELRKPKKSKSVGTFSEMMKPQSTAGELSDFTRDLTEMARQGLLEPVIGREKEVSRMVQVLCRKTKNNPVLVGDA
GVGKTALAYGLAQRIANGAIPYELQDMRVLELDMMSVVAGTRFRGDFEERMNQLIDDIEADGKIILFVDELHTIMGSGSG
IDSTLDAANILKPALSRGTLHMVGATTQEEYQKHIEKDAALSRRFAKILIEEPSVEDAYQILLGLKPSYEQYHNVTISDT
AIHTAVKLAQRYLTSKQLPDSAIDLLDEASAMVQSMVKKTQPDFITPLDQALLDGDMSKVSALLAKEDKQPKLKPTAVTE
DDMLHTLSRLSGIPLEKLTQADSKKYLNLEKELHKRVVGQEMAVSAIARAIRRNQSGIRTGRRPIGSFMFLGPTGVGKTE
LAKALAELLFDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYDEGGELTEKVRNKPYAVLLFDEVEKAHPDIFNILLQV
LDDGMLTDSRGRKVDFSNTIIIMTSNLGATALRDDKTVGFGAKAISHDHQAMEKRILEELKKAYRPEFINRIDEKVVFHS
LTQENMRDVVKIMVKPLIAALAEKHISLKFQPSALKYLSEAGYDVEMGARPLRRTLQTEVEDRLAELMLSGDLSSGQSLK
IGVSRGKLAFDIA

Nucleotide


Download         Length: 2442 bp        

>NTDB_id=1127161 FGK99_RS00830 WP_138118665.1 146993..149434(+) (clpC) [Streptococcus equi subsp. zooepidemicus strain NCTC4675]
GTGATGATTTATTCATTAAAGATGCAAGACATTTTTAATCAGGCTCAATTTCAAGCAGAGCGCTTTGATAGTCCTTACCT
TGAGACCTGGCATATTTTATTGGCTATGGTGGCTGTTGACCATTCCTTAGCGGCCATGGTGTTAAGCGAATTTGAACGAA
AGATTAGGGCTGAAGAGTATGAGGCTGCTGCTATTTTAGCCATGGGAAAAAGTCCCAAAGAGGTGACTTCTGTCCAATTC
AAGCCACAATCCAAGGCCTTATCAGAAATACTAGCATTTGCTCATGCTATCTGTCAGGTTACCAATGAGCATGAGGTTGG
CTCAGAGCATGTACTCTTTGCTATTTTGCTCAATCCGGATATTATGGCCAGTCGTCTGTTAGAGTTGGCAGGCTACAGGC
TCAAGGATTCTGGCAAGGGAGAGCCTAGGTTTGCGGATTTACGTAAGGCTATTGAGCTAAATGCCGGCTATAGCAAGGAA
ACTATTAAGGCGATTCATGAGTTGCGTAAGCCTAAAAAGAGTAAATCAGTAGGCACCTTTTCTGAAATGATGAAGCCACA
GAGTACAGCTGGTGAGCTATCAGACTTTACAAGAGACCTGACAGAGATGGCAAGACAGGGCTTATTAGAGCCAGTCATCG
GACGAGAAAAAGAGGTGTCACGTATGGTTCAGGTGCTTTGTCGTAAGACGAAAAATAATCCTGTTCTTGTTGGTGATGCG
GGTGTCGGAAAAACTGCTCTAGCTTATGGCTTAGCGCAGCGAATTGCTAATGGAGCCATTCCTTATGAATTACAAGACAT
GCGTGTCTTGGAGCTTGACATGATGAGTGTGGTTGCAGGTACCCGTTTTCGTGGGGATTTTGAAGAGCGCATGAATCAAC
TCATTGACGATATTGAAGCAGATGGTAAGATCATTTTGTTTGTCGATGAGCTACATACCATTATGGGATCAGGAAGTGGT
ATTGACAGCACACTTGATGCCGCTAATATTCTAAAGCCAGCCCTTTCTCGCGGTACCCTGCATATGGTTGGCGCTACAAC
TCAAGAGGAATATCAAAAGCACATTGAAAAGGACGCAGCTCTTTCTCGTCGCTTTGCCAAGATATTGATTGAGGAGCCTA
GTGTTGAGGACGCTTATCAGATTTTGCTTGGCTTGAAGCCTTCCTATGAACAGTACCATAATGTAACAATCTCTGATACA
GCTATCCATACTGCTGTGAAGCTGGCTCAGCGCTATTTGACAAGTAAGCAGCTTCCAGACTCAGCGATTGATCTGCTTGA
TGAAGCCAGTGCGATGGTGCAAAGTATGGTTAAAAAGACGCAGCCTGACTTTATAACACCGCTTGATCAAGCCCTGCTTG
ATGGTGATATGAGCAAGGTGTCGGCCCTTTTAGCCAAAGAGGATAAGCAACCAAAGCTAAAACCAACAGCAGTCACTGAA
GATGATATGTTACACACCTTAAGCAGGCTATCAGGTATTCCACTAGAAAAACTAACTCAGGCGGATAGTAAAAAATACCT
AAATTTGGAAAAGGAATTGCATAAGCGTGTTGTTGGTCAGGAAATGGCTGTTTCTGCTATTGCACGAGCCATTCGTCGTA
ATCAGTCAGGCATTCGCACAGGCAGACGCCCGATTGGCTCCTTTATGTTTCTTGGCCCAACCGGTGTCGGAAAAACAGAG
CTAGCAAAGGCCTTGGCCGAATTACTCTTTGATGATGAGTCAGCCCTTATTCGTTTTGACATGTCTGAGTACATGGAAAA
ATTTGCAGCCTCTCGTCTCAATGGTGCTCCTCCTGGCTATGTTGGCTATGATGAAGGAGGCGAGCTAACCGAAAAGGTTA
GAAATAAGCCTTATGCCGTTCTTCTTTTTGATGAGGTCGAAAAGGCTCACCCAGACATCTTTAATATCCTGCTGCAGGTC
CTTGATGATGGTATGTTAACAGATAGTCGTGGACGTAAGGTTGATTTTTCAAACACGATTATTATCATGACGAGCAACCT
AGGAGCAACTGCTCTGCGTGATGATAAGACTGTGGGATTTGGTGCTAAAGCGATCAGTCATGACCATCAGGCTATGGAAA
AACGTATTTTAGAGGAGCTGAAAAAGGCTTACAGACCTGAATTTATCAACAGAATTGATGAAAAGGTGGTCTTCCACAGC
CTAACACAGGAAAACATGCGTGATGTGGTCAAAATTATGGTTAAGCCGCTGATTGCAGCCTTGGCAGAAAAGCATATTAG
CCTTAAGTTCCAGCCATCAGCTCTCAAGTACTTATCTGAAGCTGGTTACGATGTTGAAATGGGTGCTCGCCCACTTCGCC
GTACCTTGCAAACAGAGGTTGAGGACAGGTTAGCAGAATTAATGCTGTCAGGAGATTTATCAAGCGGTCAAAGCCTCAAG
ATTGGTGTATCACGTGGGAAGCTAGCTTTTGATATCGCTTAA

Domains

Predicted by InterproScan.

AAA domain (Cdc48 subfamily) (AAA_2)

(543-714)

ATPase family associated with various cellular activities (AAA) (AAA)

(235-367)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(721-800)

AAA lid domain (AAA_lid_9)

(374-457)

Clp amino terminal domain, pathogenicity island component (Clp_N)

(95-131)

Clp amino terminal domain, pathogenicity island component (Clp_N)

(15-51)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpC Streptococcus mutans UA159

74.785

100

0.748
  clpC Streptococcus thermophilus LMD-9

72.426

100

0.727
  clpC Streptococcus thermophilus LMG 18311

72.181

100

0.724
  clpC Streptococcus pneumoniae Rx1

65.971

100

0.661
  clpC Streptococcus pneumoniae D39

65.971

100

0.661
  clpC Streptococcus pneumoniae TIGR4

65.848

100

0.659
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

48.743

100

0.501
  clpC Bacillus subtilis subsp. subtilis str. 168

43.952

100

0.451

Multiple sequence alignment