Detailed information NTG1126864

Bioinformatically predicted

Overview

• Name: clpE
• Type: Regulator
• Locus tag: FGK94_RS03375
• Genome accession: NZ_LR590471
• Coordinates: 733921..736176 (+)
• Length: 751 a.a.
• NCBI ID: WP_012678297.1
• Uniprot ID: -
• Organism: Streptococcus equi subsp. zooepidemicus strain NCTC11854
• Function: repress competence development (at the early growth phase) (predicted from homology) Competence regulation

Genomic Context

Location: 728921..741176

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FGK94_RS03355 (NCTC11854_00696)	-	730043..730780 (-)	738	WP_012515254.1	amino acid ABC transporter ATP-binding protein	-
FGK94_RS03360 (NCTC11854_00697)	-	730782..731465 (-)	684	WP_043029481.1	amino acid ABC transporter permease	-
FGK94_RS03365 (NCTC11854_00698)	-	731809..732963 (+)	1155	WP_138082965.1	LPXTG cell wall anchor domain-containing protein	-
FGK94_RS03370 (NCTC11854_00699)	-	733408..733638 (-)	231	WP_012515249.1	DUF1797 family protein	-
FGK94_RS03375 (NCTC11854_00700)	clpE	733921..736176 (+)	2256	WP_012678297.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
FGK94_RS03380 (NCTC11854_00701)	-	736323..736769 (+)	447	WP_012515247.1	NUDIX hydrolase	-
FGK94_RS03385 (NCTC11854_00702)	-	736831..737133 (+)	303	WP_012515246.1	DUF1827 family protein	-
FGK94_RS03390 (NCTC11854_00703)	ileS	737603..740401 (-)	2799	WP_043029479.1	isoleucine--tRNA ligase	-

Sequence

Protein

• Length: 751 a.a.
• Molecular weight: 83861.28 Da
• Isoelectric Point: 5.6718

>NTDB_id=1126864 FGK94_RS03375 WP_012678297.1 733921..736176(+) (clpE) [Streptococcus equi subsp. zooepidemicus strain NCTC11854]
MLCQNCNLNESTIHLYTSINGKQRQIDLCQNCYQIMKTDPKNPILGGYNGNQKAQQPSQNPFFDDFFGDLNNFRAFGQLP
NTPPTQSGGQHGGGHNGGYRPNQTQPTQEASKGLLEEFGINITEMAKRGDIDPVIGRDDEIIRVIEILNRRTKNNPVLIG
EPGVGKTAVVEGLAQKIVDGDVPQKLQSKQVIRLDVVSLVQGTGIRGQFEERMQKLMEEIRKRHDVILFIDEIHEIVGAG
AVGDGSMDAGNILKPALARGELQLVGATTLNEYRIIEKDAALERRMQPVKVDEPSVEETITILKGIQAKYEDYHHVKYSQ
SAIEAAANLSNRYIQDRFLPDKAIDLLDEAGSKMNLTLNFVDPKDIDKRLIEAENLKTQATRDEDYERAAYFRDQIAKYK
EMQAQKLDEQDIPIITDKTIEAIVEQKTNIPVGDLKEKEQSQLVNLAADLKKHVIGQDDAVDKIAKAIRRNRVGLGAPNR
PIGSFLFVGPTGVGKTELSKQLAIELFGSADNMIRFDMSEYMEKHAVAKLVGAPPGYVGYEEAGQLTEQVRRNPYSLILL
DEIEKAHPDVMHMFLQVLDDGRLTDGQGRTVSFKDTIIIMTSNAGTGKTEASVGFGAAREGRTNSVLGELSHFFSPEFMN
RFDGIIEFQPLSKDNLLHIVHLMLDDVNHRLAHNNIRLDVTQKVKEKLVELGYDPKMGARPLRRTIQDYIEDAITDFYLE
HPAEKDLRAVLTSNGHIIIKPVVKSQAKQAD

Nucleotide

• Length: 2256 bp

>NTDB_id=1126864 FGK94_RS03375 WP_012678297.1 733921..736176(+) (clpE) [Streptococcus equi subsp. zooepidemicus strain NCTC11854]
ATGCTTTGTCAAAACTGTAATTTAAATGAATCAACCATTCATCTTTATACAAGCATTAACGGAAAGCAAAGGCAGATTGA
CCTCTGTCAAAATTGCTACCAAATCATGAAAACAGACCCTAAAAATCCTATCTTAGGAGGCTATAATGGCAACCAAAAGG
CGCAGCAGCCTTCTCAAAACCCTTTCTTTGATGACTTTTTTGGTGACCTCAACAACTTTAGAGCCTTTGGTCAGCTCCCC
AATACACCACCTACCCAATCAGGAGGCCAGCATGGCGGAGGTCACAACGGTGGCTATCGCCCCAATCAAACACAGCCAAC
ACAGGAGGCTAGCAAGGGGCTTCTGGAGGAATTCGGCATTAATATCACTGAAATGGCTAAGCGTGGTGATATTGACCCGG
TCATCGGACGAGATGATGAGATTATCCGCGTCATCGAAATTCTCAACCGTCGTACCAAAAATAACCCTGTCCTAATCGGT
GAGCCTGGAGTTGGTAAGACTGCTGTCGTTGAAGGCCTTGCTCAAAAAATCGTTGATGGTGATGTGCCACAAAAGCTACA
GAGTAAGCAGGTGATTCGCCTTGATGTGGTTAGCCTCGTTCAGGGGACAGGTATTCGTGGCCAATTTGAAGAGCGCATGC
AAAAGCTCATGGAGGAAATCCGCAAGCGCCATGACGTTATCCTTTTTATTGATGAAATCCATGAAATTGTGGGAGCCGGG
GCAGTTGGTGATGGCAGTATGGACGCAGGAAATATTTTAAAGCCAGCACTTGCTCGTGGTGAGCTTCAATTAGTGGGAGC
CACCACTCTCAATGAATACCGCATTATCGAAAAGGACGCAGCCCTCGAACGACGCATGCAGCCGGTTAAGGTAGATGAGC
CCTCGGTTGAAGAAACAATCACGATCCTAAAAGGAATCCAAGCCAAATACGAGGACTATCACCATGTCAAATATAGCCAG
TCGGCTATTGAAGCAGCTGCTAACCTCTCCAACCGCTATATTCAAGACCGCTTCTTGCCTGATAAGGCCATTGACCTGCT
AGATGAAGCCGGCTCAAAGATGAACCTAACCCTTAACTTTGTTGACCCCAAAGACATTGATAAGCGTTTGATTGAGGCTG
AAAACCTCAAGACACAAGCCACACGTGATGAGGATTATGAGCGAGCAGCCTATTTCCGCGATCAAATCGCCAAATATAAA
GAAATGCAGGCTCAAAAGCTAGATGAGCAGGATATTCCAATCATCACTGACAAGACCATCGAAGCAATCGTTGAGCAAAA
AACCAATATTCCAGTTGGTGATTTAAAGGAAAAGGAACAATCACAGCTAGTCAATCTGGCTGCTGATCTCAAAAAGCATG
TTATCGGTCAAGACGATGCTGTTGATAAAATTGCAAAAGCTATCCGTCGTAATCGTGTTGGACTGGGAGCCCCAAATCGT
CCTATCGGCTCCTTCCTCTTTGTTGGCCCAACTGGTGTCGGTAAAACAGAGCTTTCCAAGCAATTAGCCATTGAGCTTTT
TGGCTCTGCTGATAACATGATTCGCTTTGACATGTCTGAATACATGGAAAAGCACGCTGTGGCTAAGCTTGTCGGTGCCC
CTCCCGGCTACGTCGGCTATGAGGAGGCAGGTCAGTTAACAGAGCAGGTGCGCCGCAACCCTTACTCGCTCATTTTGTTA
GATGAGATCGAAAAGGCTCACCCTGATGTCATGCACATGTTTTTACAGGTCCTAGATGACGGACGATTAACCGACGGACA
AGGACGTACCGTTAGCTTTAAGGACACTATTATCATCATGACATCAAATGCTGGCACTGGCAAAACAGAGGCCTCAGTAG
GCTTTGGCGCTGCTAGAGAAGGGCGGACAAACTCTGTTTTAGGAGAGCTCAGTCATTTCTTTAGCCCCGAGTTCATGAAT
CGCTTTGATGGCATTATTGAGTTTCAGCCACTAAGCAAGGACAATCTTTTACATATCGTTCATTTAATGCTCGATGATGT
TAACCACCGCCTTGCTCACAATAACATTCGCCTTGATGTCACCCAAAAGGTCAAAGAAAAGCTCGTTGAGCTAGGCTATG
ATCCTAAGATGGGAGCACGACCATTGCGCCGCACCATTCAGGACTACATTGAGGATGCCATTACCGACTTCTACCTTGAG
CACCCAGCAGAAAAAGACCTGCGAGCTGTCCTGACCTCTAATGGACACATTATAATCAAGCCTGTAGTCAAATCTCAGGC
GAAGCAGGCGGACTAA

Domains

Predicted by InterproScan.

• ATPase family associated with various cellular activities (AAA) (AAA) (157-270)

• AAA lid domain (AAA_lid_9) (295-392)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (651-725)

• AAA domain (Cdc48 subfamily) (AAA_2) (480-643)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpE	Streptococcus mutans UA159	84.232	98.802	0.832
clpE	Streptococcus pneumoniae Rx1	82.493	100	0.828
clpE	Streptococcus pneumoniae D39	82.493	100	0.828
clpE	Streptococcus pneumoniae R6	82.493	100	0.828
clpE	Streptococcus pneumoniae TIGR4	82.361	100	0.827
clpC	Lactococcus lactis subsp. cremoris KW2	75.532	100	0.756
clpC	Bacillus subtilis subsp. subtilis str. 168	50.074	90.146	0.451
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	46.729	85.486	0.399
clpC	Streptococcus pneumoniae Rx1	48.214	82.024	0.395
clpC	Streptococcus pneumoniae D39	48.214	82.024	0.395
clpC	Streptococcus pneumoniae TIGR4	48.052	82.024	0.394
clpC	Streptococcus mutans UA159	47.343	82.69	0.391
clpC	Streptococcus thermophilus LMD-9	46.508	83.888	0.39
clpC	Streptococcus thermophilus LMG 18311	46.19	83.888	0.387