Detailed information NTG1126200

Bioinformatically predicted

Overview

• Name: treR
• Type: Regulator
• Locus tag: E0F39_RS09755
• Genome accession: NZ_LR216060
• Coordinates: 1810206..1810916 (+)
• Length: 236 a.a.
• NCBI ID: WP_001865045.1
• Uniprot ID: A0A0T8GPJ5
• Organism: Streptococcus pneumoniae strain GPSC47 substr. ST315
• Function: regulate expression of competence genes (predicted from homology) Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
IScluster/Tn	1811071..1812377	1810206..1810916	flank	155

Gene organization within MGE regions

Location: 1810206..1812377

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
E0F39_RS09755 (SAMEA3713867_01843)	treR	1810206..1810916 (+)	711	WP_001865045.1	trehalose operon repressor	Regulator
E0F39_RS09765	-	1811071..1812377 (+)	1307	Protein_1866	transposase	-

Sequence

Protein

• Length: 236 a.a.
• Molecular weight: 27665.81 Da
• Isoelectric Point: 8.2477

>NTDB_id=1126200 E0F39_RS09755 WP_001865045.1 1810206..1810916(+) (treR) [Streptococcus pneumoniae strain GPSC47 substr. ST315]
MKKYQQLFKQIQETIQNETYAVGDFLPSEHDLMEQYQVSRDTVRKALSLLQEEGLIKKIRGQGSQVVKEETVNFPVSNLT
SYQELVKELGLRSKTNVVSLDKIIIDKKSSLITGFPEFRMVWKVVRQRVVDDLVSVLDTDYLDMELIPNLTRQIAEQSIY
SYIENDLKLLIDYAQKEITIDHSSDRDKILMDIGKDPYVVSIKSKVYLQDGRQFQFTESRHKLEKFRFVDFAKRKK

Nucleotide

• Length: 711 bp

>NTDB_id=1126200 E0F39_RS09755 WP_001865045.1 1810206..1810916(+) (treR) [Streptococcus pneumoniae strain GPSC47 substr. ST315]
ATGAAGAAATACCAACAATTATTTAAGCAAATCCAAGAAACCATTCAAAACGAGACTTACGCTGTCGGAGATTTCCTTCC
TAGCGAGCACGACCTTATGGAGCAATATCAAGTGAGTCGTGATACCGTCCGAAAGGCCCTGTCTCTCCTCCAAGAGGAAG
GATTGATCAAAAAGATAAGAGGGCAAGGTTCTCAAGTCGTCAAAGAAGAAACCGTCAATTTCCCTGTATCCAACCTAACC
AGCTACCAAGAACTAGTTAAAGAACTTGGACTGCGCTCTAAAACCAACGTGGTCAGTCTGGACAAGATTATTATTGATAA
AAAATCCTCACTGATAACCGGTTTCCCAGAGTTTCGGATGGTTTGGAAGGTGGTCCGCCAGCGTGTGGTGGATGATCTGG
TATCCGTTCTGGATACAGACTATCTGGATATGGAACTAATTCCAAATCTCACTCGCCAAATTGCTGAGCAGTCTATCTAT
TCTTATATAGAAAATGACCTCAAACTCCTTATTGATTATGCTCAGAAGGAAATCACCATTGACCACTCAAGCGACCGAGA
CAAGATTCTCATGGACATTGGCAAAGACCCTTATGTCGTTTCGATTAAATCAAAAGTCTATCTCCAAGACGGACGCCAAT
TTCAGTTTACCGAAAGTCGCCATAAGTTAGAAAAATTTAGATTTGTAGATTTTGCAAAACGCAAGAAATAA

Domains

Predicted by InterproScan.

• Bacterial regulatory proteins, gntR family (GntR) (3-66)

• UTRA domain (UTRA) (89-227)

3D structure

• AlphaFold DB: A0A0T8GPJ5

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
treR	Streptococcus mutans UA159	59.322	100	0.593