Detailed information NTG0112415

Bioinformatically predicted

Overview

• Name: kpsS
• Type: Regulator
• Locus tag: LA24_RS01870
• Genome accession: NZ_CP009419
• Coordinates: 366266..367525 (+)
• Length: 419 a.a.
• NCBI ID: WP_002223278.1
• Uniprot ID: Q05014
• Organism: Neisseria meningitidis M7124
• Function: repress natural transformation (predicted from homology) Competence regulation

Genomic Context

Location: 361266..372525

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LA24_RS01850 (LA24_01920)	rfbB	361311..362393 (+)	1083	WP_002224375.1	dTDP-glucose 4,6-dehydratase	-
LA24_RS01855 (LA24_01925)	rfbA	362456..363325 (+)	870	WP_002257595.1	glucose-1-phosphate thymidylyltransferase RfbA	-
LA24_RS01860 (LA24_01930)	rfbC	363380..363919 (+)	540	WP_002218523.1	dTDP-4-dehydrorhamnose 3,5-epimerase	-
LA24_RS01865 (LA24_01935)	-	364081..366129 (+)	2049	WP_002228852.1	capsular polysaccharide biosynthesis protein	-
LA24_RS01870 (LA24_01940)	kpsS	366266..367525 (+)	1260	WP_002223278.1	capsule biosynthesis protein	Regulator
LA24_RS01875 (LA24_01945)	-	367892..369298 (+)	1407	WP_002228855.1	tetratricopeptide repeat protein	-
LA24_RS01880 (LA24_01950)	gltS	369516..370730 (+)	1215	WP_002216198.1	sodium/glutamate symporter	-
LA24_RS01885 (LA24_01955)	-	370829..371845 (+)	1017	WP_002215314.1	lysozyme inhibitor LprI family protein	-
LA24_RS01890 (LA24_01960)	-	371856..372053 (+)	198	WP_002218528.1	hypothetical protein	-
LA24_RS13420 (LA24_01965)	-	372071..372220 (+)	150	WP_033908890.1	hypothetical protein	-

Sequence

Protein

• Length: 419 a.a.
• Molecular weight: 48701.63 Da
• Isoelectric Point: 9.0748

>NTDB_id=112415 LA24_RS01870 WP_002223278.1 366266..367525(+) (kpsS) [Neisseria meningitidis M7124]
MKQTVLKNNLQNLLESAENILLLQGPVGDFFLRLADWLTANGKTVHKFNFNAGDDYFYPPTQAHTVVFNDNYDAFPEFLQ
EYITQHHIQAVVCFGDTRPYHVIAKRIANENQASFWAFEEGYFRPYYITLEKDGVNAFSPLPRRADFFLEQFPKLAQQEY
KAPTPVHGGFTPMAKNAIRYYIELFRNPRKYPDYIHHRAPNAGHYLKPWSLSILKRLNYYIEDIQIAKRVEAGKYGKFFI
VPLQVFNDSQVRIHCDFPSVRSFLLHVLSSFAEHAPADTNIIIKHHPMDRGFIDYWRDIKRFIKEHPELKGRVIYVHDVP
LPVFLRHGLGMVTINSTSGLSGLIHNMPVKVLGRAYYDIPGITDQNTLAEFWNHPTPPDKELFHAYRMYHLNVTQINGNF
YSQVFFPNKKTSNSSTPVI

Nucleotide

• Length: 1260 bp

>NTDB_id=112415 LA24_RS01870 WP_002223278.1 366266..367525(+) (kpsS) [Neisseria meningitidis M7124]
ATGAAACAGACCGTCCTCAAAAATAACCTGCAAAACCTGCTTGAAAGCGCAGAAAATATCCTGCTGCTTCAAGGCCCTGT
CGGCGATTTTTTTCTGCGCCTTGCCGACTGGCTGACTGCAAACGGCAAAACCGTACATAAATTCAACTTTAATGCAGGCG
ACGACTATTTTTATCCGCCCACTCAAGCGCATACCGTTGTTTTTAACGACAACTACGATGCCTTTCCTGAGTTTTTGCAA
GAATACATCACTCAACATCACATCCAGGCCGTTGTCTGCTTTGGCGACACACGCCCTTATCACGTCATTGCAAAACGCAT
TGCAAACGAAAACCAAGCCAGTTTCTGGGCGTTTGAAGAAGGCTATTTCCGCCCCTACTACATCACCTTAGAAAAAGACG
GCGTCAACGCATTTTCCCCGTTGCCGCGCCGTGCCGACTTTTTTCTTGAACAATTCCCTAAGCTTGCCCAGCAAGAATAT
AAAGCGCCAACGCCGGTACACGGCGGTTTTACGCCCATGGCAAAAAACGCTATCCGTTACTATATCGAGTTGTTCCGCAA
TCCACGCAAATACCCCGACTACATCCACCACCGCGCACCCAATGCCGGCCATTACCTCAAACCGTGGTCGCTCTCCATCC
TCAAGCGTTTGAACTACTATATTGAAGACATCCAAATCGCCAAACGTGTGGAAGCAGGCAAATACGGCAAGTTTTTTATT
GTTCCCTTACAGGTATTCAACGACAGCCAAGTCCGTATCCATTGCGACTTTCCCAGCGTCCGCAGCTTCCTGCTCCATGT
TTTGAGTTCATTTGCCGAGCACGCGCCTGCCGATACCAACATCATCATCAAGCATCATCCGATGGACCGCGGTTTTATCG
ACTACTGGCGCGACATTAAACGCTTTATCAAAGAACACCCCGAACTCAAAGGCCGCGTGATTTATGTCCATGATGTCCCC
CTGCCCGTTTTCCTGCGCCACGGTCTCGGCATGGTCACCATCAACAGCACCAGCGGCCTGTCCGGACTGATTCACAATAT
GCCAGTTAAGGTTCTCGGCCGTGCCTATTATGATATTCCCGGCATTACTGACCAAAATACCTTGGCAGAATTTTGGAATC
ATCCGACACCGCCTGACAAAGAGCTGTTCCATGCCTACCGAATGTACCACCTCAACGTGACCCAAATTAACGGCAACTTC
TACAGTCAGGTGTTTTTCCCCAACAAAAAAACCTCCAACTCTTCCACACCAGTAATCTGA

Domains

Predicted by InterProScan.

• Capsule polysaccharide biosynthesis protein (Capsule_synth) (89-401)

3D structure

• AlphaFold DB: Q05014

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
kpsS	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	38.579	94.033	0.363