Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   EL323_RS00325 Genome accession   NZ_LR134526
Coordinates   56024..59149 (-) Length   1041 a.a.
NCBI ID   WP_105184309.1    Uniprot ID   -
Organism   Neisseria meningitidis strain NCTC10026     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 51024..64149
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL323_RS14305 - 51194..51361 (-) 168 WP_153312129.1 hypothetical protein -
  EL323_RS00290 (NCTC10026_00047) - 51365..51754 (-) 390 WP_002219820.1 endonuclease domain-containing protein -
  EL323_RS15360 - 51934..52279 (+) 346 Protein_49 hypothetical protein -
  EL323_RS00300 (NCTC10026_00048) - 52314..52451 (-) 138 WP_002243840.1 VOC family protein -
  EL323_RS00305 (NCTC10026_00049) carA 52505..53638 (-) 1134 WP_002217954.1 glutamine-hydrolyzing carbamoyl-phosphate synthase small subunit -
  EL323_RS00325 (NCTC10026_00050) pilC 56024..59149 (-) 3126 WP_105184309.1 PilC family type IV pilus tip adhesin Machinery gene
  EL323_RS00340 (NCTC10026_00051) apbC 60286..61365 (-) 1080 WP_080542403.1 iron-sulfur cluster carrier protein ApbC -
  EL323_RS00350 (NCTC10026_00053) - 61735..62244 (+) 510 WP_002225670.1 protein disulfide oxidoreductase -
  EL323_RS00360 (NCTC10026_00054) nadR 62585..63025 (+) 441 WP_002214596.1 MarR family adhesin repressor NadR -
  EL323_RS00365 (NCTC10026_00055) hpaC 63140..63640 (+) 501 WP_002223009.1 4-hydroxyphenylacetate 3-monooxygenase, reductase component -

Sequence

Protein


Download         Length: 1041 a.a.        Molecular weight: 113998.02 Da        Isoelectric Point: 9.7529

>NTDB_id=1123954 EL323_RS00325 WP_105184309.1 56024..59149(-) (pilC) [Neisseria meningitidis strain NCTC10026]
MNKTLKRRVFRHTALYAAILMFSHTGGGGAQAQTSKYAIIMNEGNQLEVKQNGQYSTIKDKDREREYTHHQPAVGGGSVS
FNNSDELVSRQSGTAVFGTATYLPPYGKVSGFDADALKERNNAVDWIRTTRIALAGYSYADVVCRSNAGCPKLVYKTRFS
FDNPDLVKIGGGLDRHTEPSRDNSPIYKLKDHPWLGVSFNLGAEGTAKNGKVTNKLVSSFDEKNSNNNLVYTTESGDISL
GNRHRETTAMAYYLNAKLHLLNKKQIQNITDKTVLLGVLRPSIDVRQGNTGIAGILSFWTKWDIKDDGQIPVKLGLPQVK
AGRCINKPNPNNNTKVPSPALTAPALWFGPVQNGKAEMYSASVSTYPDSSSSQIFLQNLSRKDDTSKPGRYSLKPLSTSE
IKSKEPTFTGRQTVIRLDGGVQQIKLSRNNDEVVNFNVNNGKNNTFGIVREGSFTPDASEWKKVLLPWTVRASNDDNQFK
TINQQLNQQKIQYSQRYRIRENGNNSKRDLGDIVNSPIVAVGGYLATSANDGMVHIFKQSGGDKRGYNLKLSYIPGTMPR
KDIQNTESTLAKELRAFAEKGYVGDRYGVDGGFVLRRITDDQDKQKHFFMFGAMGLGGRGAYALDLTKADDNDPTKASLF
DVKDNGNNGNNGNNRVELGYTVGTPQIGKTHNGKYAAFLASGYATKQIDSGENKTALYVYDLESNNGTLIRKIEVTDGKG
GLSSPTLVDKDLDGTVDIAYAGDRGGKMYRFDLSGNNPNSWTVRTIFQDTKPITSAPAISQLKDKRVVIFGTGSDLSEED
VLNTEEQHIYGIFDDDTAASNVDVKLKGLGGGLLEQELKQEGKTLFLTDYKRSDGSGDKGWVVKLQPGQRVTVKPTVVLR
TAFVTIHKYTGNDKCGAETAILGINTADGGKLTKKSARPIVPDANKDVAQYSGHKQTAKGKSIPIGCMEKNGGTVCPNGY
VYDKPVNVRYLDEKKTDGFSTTADGDAGGSGTFKEGKKPARNNRCFSGKGVRTLLMNDLDSLDITGPMCGMKRISWREVF
Y

Nucleotide


Download         Length: 3126 bp        

>NTDB_id=1123954 EL323_RS00325 WP_105184309.1 56024..59149(-) (pilC) [Neisseria meningitidis strain NCTC10026]
ATGAATAAAACTTTAAAAAGGCGGGTTTTCCGCCATACCGCGCTTTATGCCGCCATCTTGATGTTTTCCCATACCGGCGG
GGGGGGGGCGCAGGCGCAAACCAGTAAATACGCTATTATCATGAACGAGGGAAACCAGCTCGAGGTAAAGCAGAATGGGC
AATATTCAACAATAAAGGACAAAGACAGGGAGCGCGAATATACTCATCATCAGCCCGCAGTAGGAGGAGGCTCTGTCTCA
TTCAACAATAGCGATGAGCTTGTTTCTCGACAAAGCGGTACTGCCGTTTTTGGCACAGCCACCTACCTGCCGCCCTACGG
CAAGGTTTCCGGTTTTGATGCCGACGCTCTGAAAGAGCGCAACAATGCCGTCGATTGGATTCGTACCACCCGCATCGCGC
TGGCAGGCTACAGCTACGCCGATGTCGTATGCAGAAGCAACGCAGGCTGTCCCAAACTTGTCTATAAAACCCGATTTTCC
TTCGATAATCCCGACTTGGTAAAAATAGGAGGCGGGCTGGATAGGCACACAGAGCCAAGCCGCGACAATTCGCCCATTTA
CAAATTGAAGGATCATCCATGGTTGGGCGTGTCTTTCAATTTGGGCGCCGAGGGTACCGCCAAAAATGGTAAGGTAACCA
ACAAATTGGTATCTTCTTTTGATGAAAAGAATAGTAATAACAACCTCGTCTATACCACGGAAAGCGGCGATATTTCCTTG
GGCAACAGGCATCGCGAAACGACCGCCATGGCCTATTATCTGAACGCCAAGCTGCACCTGCTGAATAAAAAACAGATTCA
AAATATCACCGACAAAACAGTGCTGTTGGGTGTCTTGAGGCCGAGCATCGATGTGCGGCAAGGAAATACGGGGATTGCCG
GCATTCTATCTTTTTGGACTAAGTGGGACATTAAAGATGACGGGCAGATTCCAGTCAAGCTCGGCCTGCCGCAAGTCAAA
GCAGGCCGCTGCATCAACAAACCGAACCCCAATAATAATACCAAAGTCCCCTCCCCCGCACTGACTGCCCCCGCGCTGTG
GTTCGGACCTGTGCAAAATGGTAAGGCGGAGATGTATTCCGCTTCGGTTTCCACCTACCCCGACAGTTCGAGCAGCCAAA
TTTTCCTGCAAAACCTTTCCCGCAAGGATGACACAAGCAAACCGGGCCGCTATTCCCTCAAACCCTTGAGTACGTCGGAG
ATTAAAAGTAAAGAGCCGACTTTCACAGGGCGGCAAACCGTCATCCGATTGGATGGCGGCGTGCAGCAGATCAAACTGAG
TAGAAACAATGATGAGGTCGTCAATTTTAATGTAAACAACGGCAAAAACAACACTTTCGGCATTGTTAGAGAAGGGAGCT
TCACGCCTGATGCCAGCGAGTGGAAAAAAGTATTGCTGCCTTGGACGGTTCGTGCTTCCAATGATGACAATCAATTTAAA
ACAATTAACCAACAACTTAACCAACAAAAAATCCAATACAGCCAAAGATACCGCATCCGCGAAAACGGCAACAATAGCAA
GCGTGATTTGGGCGACATCGTCAACAGCCCCATCGTGGCGGTCGGCGGGTATTTGGCAACTTCTGCCAACGACGGGATGG
TGCATATCTTCAAACAAAGCGGCGGGGACAAGCGCGGCTACAATCTGAAGCTCAGTTATATCCCGGGTACGATGCCGCGC
AAGGATATTCAAAACACCGAATCCACCCTTGCCAAAGAGCTGCGCGCCTTTGCCGAAAAAGGCTATGTGGGCGACCGCTA
CGGCGTGGACGGCGGCTTTGTCTTGCGCCGCATTACAGATGACCAAGACAAGCAAAAACACTTCTTTATGTTCGGCGCAA
TGGGCCTTGGCGGCAGAGGCGCATACGCCTTGGATTTGACCAAAGCCGACGACAATGACCCGACAAAAGCCTCTTTGTTT
GATGTAAAAGATAACGGCAATAATGGCAATAACGGCAATAATCGCGTGGAATTAGGCTACACCGTCGGCACGCCGCAAAT
CGGCAAAACCCACAACGGCAAATACGCCGCCTTCCTCGCCTCCGGTTATGCGACTAAACAGATTGACAGCGGCGAGAATA
AAACCGCGCTGTATGTGTATGATTTGGAAAGCAACAACGGTACGCTGATTAGAAAAATCGAAGTAACCGACGGCAAGGGC
GGGCTTTCGTCCCCCACGCTGGTGGATAAAGATTTGGACGGCACGGTCGATATCGCCTATGCCGGCGATCGCGGCGGCAA
GATGTACCGCTTTGATTTAAGCGGCAACAACCCGAACAGTTGGACTGTACGCACTATTTTCCAAGACACGAAGCCGATTA
CTTCCGCGCCCGCCATTTCCCAACTGAAAGACAAACGCGTGGTTATCTTCGGCACGGGCAGCGATTTGAGTGAAGAGGAT
GTACTCAATACGGAAGAACAACATATTTACGGTATCTTTGACGACGATACGGCGGCGAGTAATGTAGATGTAAAACTCAA
AGGTTTGGGAGGCGGGTTGCTCGAGCAAGAGCTTAAGCAGGAGGGTAAAACCTTATTCCTGACCGATTACAAGCGATCCG
ACGGCTCGGGCGACAAGGGCTGGGTAGTGAAATTGCAGCCCGGACAGCGCGTTACCGTCAAACCGACCGTGGTATTGCGT
ACCGCCTTTGTAACCATCCATAAATATACGGGTAATGACAAATGCGGCGCGGAAACCGCCATTTTGGGCATCAATACCGC
CGACGGCGGCAAGCTGACGAAGAAAAGCGCGCGCCCGATTGTGCCGGACGCCAATAAGGATGTCGCGCAATATTCCGGTC
ATAAGCAAACCGCCAAAGGCAAATCCATCCCTATAGGTTGTATGGAAAAAAACGGGGGAACCGTCTGCCCGAACGGATAT
GTTTACGACAAACCGGTTAATGTGCGTTATCTGGATGAAAAGAAAACAGACGGATTTTCAACAACGGCAGACGGTGATGC
GGGCGGCAGCGGAACATTCAAAGAGGGTAAAAAACCCGCCCGCAATAACCGCTGCTTCTCCGGAAAAGGTGTGCGCACCC
TGCTGATGAACGATTTGGACAGCTTGGACATTACCGGCCCGATGTGCGGTATGAAACGAATCAGCTGGCGTGAAGTCTTC
TACTGA

Domains

Predicted by InterproScan.

Neisseria PilC beta-propeller domain (T4P_PilY1)

(510-848)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Neisseria meningitidis A1493

75.977

100

0.766

Multiple sequence alignment