Detailed information NTG0112386

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: LA50_RS09930
• Genome accession: NZ_CP009418
• Coordinates: 1879410..1881989 (-)
• Length: 859 a.a.
• NCBI ID: WP_002248313.1
• Uniprot ID: -
• Organism: Neisseria meningitidis strain NM3686
• Function: degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 1874410..1886989

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LA50_RS09910 (LA50_10445)	-	1875337..1876602 (+)	1266	WP_002221776.1	Glu/Leu/Phe/Val family dehydrogenase	-
LA50_RS09915 (LA50_10450)	-	1876660..1877466 (-)	807	WP_002212946.1	DUF4198 domain-containing protein	-
LA50_RS09920 (LA50_10455)	-	1877811..1878020 (+)	210	WP_002212949.1	tautomerase family protein	-
LA50_RS09925 (LA50_10460)	-	1878109..1879323 (+)	1215	WP_002220612.1	pyridoxal phosphate-dependent aminotransferase	-
LA50_RS09930 (LA50_10465)	clpC	1879410..1881989 (-)	2580	WP_002248313.1	ATP-dependent chaperone ClpB	Regulator
LA50_RS09935 (LA50_10470)	trpS	1882250..1883260 (+)	1011	WP_002226234.1	tryptophan--tRNA ligase	-
LA50_RS09940 (LA50_10475)	-	1883266..1883607 (+)	342	WP_002220616.1	hypothetical protein	-
LA50_RS09945 (LA50_10480)	-	1883927..1884292 (+)	366	WP_002220617.1	Ag473 family lipoprotein	-
LA50_RS09950 (LA50_10485)	ppx	1884501..1886009 (-)	1509	WP_002220619.1	exopolyphosphatase	-
LA50_RS09955 (LA50_10490)	-	1886126..1886857 (-)	732	WP_002220620.1	surface lipoprotein assembly modifier	-

Sequence

Protein

• Length: 859 a.a.
• Molecular weight: 95063.51 Da
• Isoelectric Point: 5.3089

>NTDB_id=112386 LA50_RS09930 WP_002248313.1 1879410..1881989(-) (clpC) [Neisseria meningitidis strain NM3686]
MRYDKLTAKFQQALAEAQSLALAADGSCLEAGFVLKALLDDQNSGAAALLAHAGVNVPQVKQRLQQHLNSLPKVSGQGGD
ILPSRELQAVLNLMDKAATKRGDAYIASELFLLALVQQNDAAGKILKEAGATEQNINAAIDAVRGGQNVNDANAEDQRDA
LKKYTLDLTQRARDGKLDPVIGRDDEIRRAIQVLQRRTKNNPVLIGEPGVGKTAIVEGLAQRIVNGEVPESLRNKRLLVL
DLAALIAGAKYRGEFEERLKGVLNDLAKDDGNTLIFIDEIHTLVGAGKTDGAMDAGNMLKPALARGELHCIGATTLDEYR
QYIEKDAALERRFQKVLVGEPSVEDTIAILRGLQERYEIHHGIDITDPAIVAAAELSDRYITDRFLPDKAIDLIDEAASR
VKMEKETKPEAMDKIDRRLIQLRMEKAHVEKEKDDASKKRLELIDEEINGLQKEYADLDEIWKAEKAISDGAANIKKQID
EVKIKIEQAKRQGDLALASKLMYEDLEHLEKQRAAAERADTDSTKPANKLLRNNVGAEEIAEVVSRMTGIPVSKMMEGER
DKLLKMEEVLHRRVVGQDEAVRAVSDAIRRSRSGLADPNKPYGSFLFLGPTGVGKTELCKALAGFLFDSEDHLIRIDMSE
YMEKHAVARLIGAPPGYVGYEEGGYLTEQVRRKPYSVILLDEVEKAHPDVFNILLQVLDDGRLTDGQGRTVDFKNTVIVM
TSNIGSQHIQQMSIQDYEAVKEVVMEDVKEHFRPEMINRIDEVVVFHGLDQANIRSIAKIQLKGLEKRLEKQNLRLTVSD
AALDIIAKAGFDPIYGARPLKRAIQSEIENPLAKALLAGNYAPESEIRVEADGDRLKFA

Nucleotide

• Length: 2580 bp

>NTDB_id=112386 LA50_RS09930 WP_002248313.1 1879410..1881989(-) (clpC) [Neisseria meningitidis strain NM3686]
ATGCGATACGACAAATTAACCGCCAAATTCCAACAGGCCCTTGCAGAAGCTCAGAGTTTGGCGTTGGCTGCGGACGGCAG
CTGTCTGGAAGCGGGCTTTGTGCTGAAAGCCCTGCTTGACGACCAAAACAGCGGTGCTGCCGCGCTCTTGGCTCATGCGG
GCGTGAACGTGCCGCAGGTGAAACAGCGTTTGCAGCAGCATTTGAACAGCCTGCCGAAAGTGTCCGGCCAGGGCGGCGAC
ATTCTGCCCAGCCGCGAATTGCAGGCGGTGTTGAACCTGATGGACAAAGCCGCAACCAAACGCGGCGATGCCTATATCGC
CAGTGAACTTTTCCTGCTTGCCTTGGTGCAGCAGAACGATGCGGCCGGCAAAATTTTGAAAGAAGCCGGCGCGACCGAAC
AAAACATCAATGCCGCGATTGACGCGGTACGAGGAGGACAAAACGTGAACGATGCCAATGCCGAAGACCAACGCGATGCT
TTGAAAAAATATACGCTCGATCTGACCCAACGCGCCCGAGACGGTAAGCTCGACCCCGTTATCGGCCGTGACGACGAAAT
CCGCCGTGCGATTCAGGTATTGCAACGCCGTACCAAAAACAACCCTGTGCTGATTGGCGAACCGGGCGTGGGTAAAACCG
CCATCGTCGAAGGTTTGGCACAACGCATCGTCAACGGCGAAGTACCCGAATCCCTGCGCAACAAACGCCTACTGGTTTTG
GACTTGGCGGCATTGATTGCCGGCGCGAAATACCGCGGCGAATTTGAAGAACGCTTGAAAGGCGTGTTGAACGACTTGGC
GAAAGACGACGGCAACACTCTGATTTTCATCGACGAAATCCATACTTTGGTCGGCGCAGGCAAAACCGACGGTGCGATGG
ATGCGGGCAATATGCTGAAACCGGCTTTGGCACGTGGCGAATTGCACTGTATCGGCGCGACCACCTTGGACGAATACCGC
CAATACATCGAAAAAGACGCGGCACTCGAACGCCGCTTCCAAAAAGTATTGGTTGGCGAGCCAAGTGTAGAAGACACCAT
CGCTATCTTGCGCGGTTTACAGGAGCGTTATGAAATCCACCACGGTATCGATATTACCGACCCTGCTATCGTTGCCGCAG
CGGAGTTGAGCGACCGCTACATTACCGACCGCTTCCTGCCTGATAAAGCGATTGATTTGATTGACGAAGCCGCCAGCCGT
GTCAAGATGGAAAAAGAAACCAAGCCGGAAGCAATGGACAAAATCGACCGCCGTCTAATTCAGCTTCGGATGGAAAAGGC
GCACGTTGAAAAAGAAAAAGACGATGCCAGCAAAAAACGTTTGGAACTGATAGACGAGGAAATCAACGGTCTGCAAAAAG
AATACGCCGATTTAGACGAAATCTGGAAAGCCGAAAAAGCAATTTCAGACGGTGCTGCTAATATTAAGAAACAAATTGAC
GAAGTCAAAATTAAAATCGAACAGGCAAAACGGCAAGGCGATTTGGCACTGGCTTCAAAATTGATGTATGAAGATTTGGA
GCATTTGGAAAAACAGCGTGCAGCCGCCGAACGGGCAGATACGGACAGCACAAAACCGGCAAACAAACTCTTGCGTAATA
ATGTCGGCGCAGAGGAAATCGCAGAGGTGGTTTCCCGTATGACCGGCATTCCCGTATCCAAAATGATGGAAGGCGAACGC
GACAAACTGCTGAAAATGGAAGAAGTATTGCACCGCCGCGTGGTCGGACAGGACGAAGCCGTGCGTGCCGTGTCCGACGC
TATCCGCCGCAGCCGCTCCGGTCTTGCCGATCCGAACAAGCCTTACGGCAGCTTCCTGTTCTTGGGCCCGACCGGCGTGG
GTAAAACCGAGTTGTGTAAAGCCCTGGCAGGCTTTCTGTTCGACAGCGAAGATCATCTGATTCGCATCGATATGTCCGAA
TATATGGAAAAACACGCCGTTGCACGCCTGATCGGTGCGCCTCCGGGCTATGTCGGCTACGAAGAAGGCGGCTACCTGAC
CGAACAAGTGCGCCGCAAACCGTACAGCGTGATTCTGCTGGACGAAGTGGAAAAAGCCCATCCCGATGTGTTCAACATCC
TGCTGCAAGTATTGGATGACGGTCGTTTGACCGACGGGCAAGGCAGGACGGTAGATTTTAAAAATACCGTGATTGTGATG
ACTTCCAACATCGGCAGCCAGCACATCCAACAAATGAGCATTCAGGATTACGAAGCGGTAAAAGAAGTTGTGATGGAGGA
TGTGAAAGAACATTTCCGTCCTGAAATGATCAACCGCATCGACGAAGTGGTCGTGTTCCACGGTTTGGATCAGGCAAACA
TCCGCAGCATTGCGAAAATCCAGCTCAAAGGTTTGGAAAAACGTTTGGAAAAACAAAACCTGCGCCTGACTGTTTCCGAT
GCCGCACTGGACATCATCGCCAAAGCCGGTTTCGACCCGATTTACGGCGCACGTCCGCTCAAACGCGCCATCCAGTCGGA
AATCGAAAACCCGCTGGCAAAAGCCCTGCTTGCCGGAAACTATGCGCCCGAAAGCGAAATCAGGGTAGAAGCCGACGGCG
ACAGACTGAAATTTGCCTGA

Domains

Predicted by InterProScan.

• Clp amino terminal domain, pathogenicity island component (Clp_N) (17-68)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (96-145)

• AAA domain (Cdc48 subfamily) (AAA_2) (601-763)

• AAA lid domain (AAA_lid_9) (342-442)

• ATPase family associated with various cellular activities (AAA) (AAA) (203-336)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (769-849)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Bacillus subtilis subsp. subtilis str. 168	43.902	100	0.44
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	38.393	100	0.4
clpC	Streptococcus pneumoniae TIGR4	40.904	95.343	0.39
clpC	Streptococcus pneumoniae Rx1	40.904	95.343	0.39
clpC	Streptococcus pneumoniae D39	40.904	95.343	0.39
clpC	Lactococcus lactis subsp. cremoris KW2	46.983	81.024	0.381
clpE	Streptococcus pneumoniae TIGR4	46.793	79.86	0.374