Detailed information NTG1123824

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: EL267_RS08385
• Genome accession: NZ_LR134520
• Coordinates: 1648806..1649879 (-)
• Length: 357 a.a.
• NCBI ID: WP_000796095.1
• Uniprot ID: A0A0E1EG10
• Organism: Streptococcus agalactiae strain NCTC13947
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1643806..1654879

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EL267_RS08365 (NCTC13947_01664)	-	1645080..1645595 (-)	516	WP_000919803.1	VanZ family protein	-
EL267_RS08370 (NCTC13947_01665)	rlmN	1645595..1646701 (-)	1107	WP_001124990.1	23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN	-
EL267_RS08375 (NCTC13947_01666)	-	1646752..1647330 (-)	579	WP_001224500.1	YutD family protein	-
EL267_RS08380	-	1647399..1648731 (-)	1333	Protein_1592	bifunctional metallophosphatase/5'-nucleotidase	-
EL267_RS08385 (NCTC13947_01669)	sepM	1648806..1649879 (-)	1074	WP_000796095.1	SepM family pheromone-processing serine protease	Regulator
EL267_RS08390 (NCTC13947_01670)	coaD	1649869..1650354 (-)	486	WP_000161892.1	pantetheine-phosphate adenylyltransferase	-
EL267_RS08395 (NCTC13947_01671)	-	1650351..1650641 (-)	291	WP_000384889.1	hypothetical protein	-
EL267_RS08400 (NCTC13947_01672)	rsmD	1650653..1651192 (-)	540	WP_001266831.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
EL267_RS08410 (NCTC13947_01673)	-	1651322..1651771 (+)	450	WP_000592263.1	thiol reductase thioredoxin	-
EL267_RS08415 (NCTC13947_01674)	asnA	1651816..1652808 (-)	993	WP_000748011.1	aspartate--ammonia ligase	-
EL267_RS08420 (NCTC13947_01675)	-	1652922..1653986 (-)	1065	WP_000021304.1	MmcQ/YjbR family DNA-binding protein	-

Sequence

Protein

• Length: 357 a.a.
• Molecular weight: 39199.43 Da
• Isoelectric Point: 10.4385

>NTDB_id=1123824 EL267_RS08385 WP_000796095.1 1648806..1649879(-) (sepM) [Streptococcus agalactiae strain NCTC13947]
MKNRDPKRKHKSLLGLLKWWIIGFAFLLLVLASLVVRLPYYLEMPGGAYDIRSVLKVNKKADKAKGSYNFVAVSVSQATP
AQVLYAWLTPFTELSSKEETTGGFSNDDYLRINQFYMETSQNESIYQALKLANKQVSLTYKGVYVLNLAKNSTFKDRLHL
ADTVTGVNGKSFKNSSQLIKYVAALHLGDKVKVQYTSQGKKKESVGKVIKLSNGKNGIGIGLTDHTEVLSDVPVDFNTEG
VGGPSAGLMFTLAIYDQLVKEDLRKGRKIAGTGTIEQNGHVGDIGGAGLKVVSAAKKGMDIFFVPNNPIDKNAKKGKTKV
QTNYQEAKAAAKRLGTKMKIVPVQNVQQAIDYLKKTK

Nucleotide

• Length: 1074 bp

>NTDB_id=1123824 EL267_RS08385 WP_000796095.1 1648806..1649879(-) (sepM) [Streptococcus agalactiae strain NCTC13947]
GTGAAGAATAGAGATCCAAAAAGAAAACATAAAAGTTTACTAGGTCTGCTTAAATGGTGGATTATAGGTTTTGCTTTTTT
ATTGTTAGTATTAGCAAGCCTTGTAGTGAGACTACCTTATTATTTGGAAATGCCAGGTGGAGCTTATGATATCCGTTCGG
TATTGAAAGTGAATAAAAAGGCTGATAAAGCTAAGGGTTCGTACAATTTTGTAGCGGTATCTGTCAGTCAAGCAACGCCA
GCTCAGGTTCTTTATGCTTGGTTAACTCCTTTTACAGAATTATCTAGTAAAGAGGAGACAACAGGTGGCTTTAGTAATGA
CGATTATCTCAGAATTAATCAATTCTACATGGAGACTTCTCAAAATGAGTCCATCTATCAAGCTTTAAAGTTAGCTAATA
AGCAAGTATCTCTTACTTATAAAGGAGTTTATGTGCTTAACTTAGCTAAAAATTCGACATTTAAAGATAGATTACATTTA
GCTGATACAGTCACAGGAGTTAATGGCAAAAGTTTCAAAAATTCTTCTCAACTTATCAAATATGTTGCAGCTCTTCATCT
AGGTGATAAAGTAAAGGTACAATACACAAGTCAAGGTAAAAAGAAAGAATCAGTTGGTAAAGTTATTAAACTATCAAACG
GTAAAAATGGTATTGGTATCGGTTTGACAGACCATACAGAAGTATTATCTGATGTTCCTGTGGACTTTAATACTGAAGGT
GTTGGAGGACCAAGTGCAGGTTTAATGTTTACTTTAGCGATTTACGACCAATTGGTTAAAGAAGATTTACGTAAAGGACG
TAAGATTGCAGGTACTGGTACTATTGAGCAAAATGGGCATGTTGGCGATATTGGTGGAGCAGGTTTGAAAGTTGTTTCAG
CGGCTAAAAAAGGAATGGATATTTTCTTTGTTCCTAATAATCCGATCGATAAAAATGCTAAAAAAGGCAAAACAAAGGTT
CAGACGAATTATCAAGAGGCAAAAGCAGCAGCTAAGCGATTAGGTACGAAGATGAAAATTGTACCAGTTCAAAATGTTCA
GCAAGCTATTGATTATTTGAAAAAAACAAAATAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (137-203)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (242-307)

3D structure

• AlphaFold DB: A0A0E1EG10

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	69.322	94.958	0.658