Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilA   Type   Machinery gene
Locus tag   EL276_RS09515 Genome accession   NZ_LR134516
Coordinates   2053097..2054467 (-) Length   456 a.a.
NCBI ID   WP_126305080.1    Uniprot ID   A0A448UE49
Organism   Neisseria animaloris strain NCTC12227     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2048097..2059467
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL276_RS09490 (NCTC12227_01927) - 2049125..2050021 (+) 897 WP_107879828.1 patatin-like phospholipase family protein -
  EL276_RS09495 (NCTC12227_01928) pncC 2050233..2050706 (-) 474 WP_107879803.1 nicotinamide-nucleotide amidase -
  EL276_RS09500 (NCTC12227_01929) ftsX 2051008..2051922 (-) 915 WP_126305079.1 permease-like cell division protein FtsX -
  EL276_RS09505 (NCTC12227_01930) ftsE 2051919..2052572 (-) 654 WP_085390592.1 cell division ATP-binding protein FtsE -
  EL276_RS09510 (NCTC12227_01931) - 2052777..2053028 (+) 252 WP_085390590.1 BolA family protein -
  EL276_RS09515 (NCTC12227_01932) pilA 2053097..2054467 (-) 1371 WP_126305080.1 signal recognition particle-docking protein FtsY Machinery gene
  EL276_RS09520 (NCTC12227_01933) - 2054674..2055120 (+) 447 WP_107879806.1 PH domain-containing protein -
  EL276_RS09525 (NCTC12227_01934) - 2055234..2056559 (+) 1326 WP_126305081.1 M16 family metallopeptidase -
  EL276_RS09530 (NCTC12227_01935) thiS 2056630..2056824 (+) 195 WP_107929229.1 sulfur carrier protein ThiS -
  EL276_RS09535 (NCTC12227_01936) yciA 2056871..2057326 (+) 456 WP_085390581.1 acyl-CoA thioester hydrolase YciA -
  EL276_RS09540 (NCTC12227_01937) - 2057450..2058244 (+) 795 WP_126305082.1 thiazole synthase -

Sequence

Protein


Download         Length: 456 a.a.        Molecular weight: 48747.32 Da        Isoelectric Point: 4.3397

>NTDB_id=1123740 EL276_RS09515 WP_126305080.1 2053097..2054467(-) (pilA) [Neisseria animaloris strain NCTC12227]
MFSFFKRKKKQETAETVAEPVQKPVSETGAEIADEPSALEISTPETLEPLTETQLEAVEEHEESSVLDQLVSGVVSGSSE
LPEQYDPNAPVAKIHVSPIPEGDAAPVEEAAELNSSELADALRLPDSIATMTAPVVAAADEPAEPVTEEDEPAKLGWAAR
LKKGLTKSRDQMAKSLAGVFGGGQIDEDLYEELETVLITSDMGMEATEYLMKDVRKRVSLRGLKDGNELRGALKDAIYDL
IKPLQKPLVIPDNGQPFVIMLAGINGAGKTTSIGKLAKYFQSQGKSVLLAAGDTFRAAAREQLQEWGARNGVTVISQSTG
DSAAVCFDAVEAAKARGIDIVLADTAGRLPTQLHLMEEIKKVKRVLQKSMPEAPHEIIVVLDANIGQNAINQVVAFDDAL
DVTGLIVTKLDGTAKGGILAALASNRPIPVRYIGVGESIDDLRPFDARAFVDALFD

Nucleotide


Download         Length: 1371 bp        

>NTDB_id=1123740 EL276_RS09515 WP_126305080.1 2053097..2054467(-) (pilA) [Neisseria animaloris strain NCTC12227]
ATGTTCAGCTTCTTTAAACGCAAGAAAAAACAGGAAACTGCCGAAACCGTTGCCGAACCTGTGCAAAAGCCGGTATCGGA
AACGGGTGCCGAAATCGCGGACGAGCCGTCCGCCCTTGAAATCTCCACGCCCGAAACCCTCGAACCGCTGACCGAAACCC
AGCTTGAAGCGGTAGAAGAACATGAAGAAAGCAGCGTGCTTGACCAGTTGGTGTCGGGCGTGGTTTCCGGCAGCAGCGAA
TTGCCCGAACAATACGATCCGAATGCGCCGGTAGCCAAAATCCATGTTTCGCCGATACCCGAAGGCGATGCCGCACCGGT
GGAAGAGGCGGCCGAACTCAACAGCAGCGAATTGGCCGATGCTTTGAGATTGCCCGACAGCATCGCTACGATGACTGCGC
CGGTGGTTGCCGCTGCCGACGAGCCTGCCGAACCTGTGACGGAGGAAGACGAACCAGCCAAGCTCGGTTGGGCGGCGCGT
TTGAAAAAAGGCTTAACCAAATCGCGCGACCAAATGGCCAAATCGCTGGCCGGCGTATTCGGCGGCGGCCAGATCGACGA
AGACCTTTATGAAGAATTGGAAACCGTGCTGATTACCAGCGATATGGGCATGGAAGCCACCGAATATCTGATGAAAGACG
TGCGCAAACGCGTGTCGCTACGCGGGTTGAAAGACGGTAACGAGTTGCGCGGCGCCTTGAAAGACGCGATTTATGATTTG
ATCAAGCCGTTGCAGAAACCGCTGGTGATTCCCGACAACGGGCAGCCTTTTGTGATTATGCTGGCCGGCATCAATGGCGC
GGGCAAAACCACTTCTATCGGCAAACTGGCCAAATATTTCCAATCGCAAGGTAAGTCGGTGCTGCTGGCGGCGGGCGATA
CTTTCCGTGCCGCCGCCCGCGAGCAGTTGCAGGAATGGGGCGCGCGCAACGGCGTGACCGTGATTTCGCAAAGCACGGGC
GATTCCGCCGCCGTCTGCTTCGATGCCGTAGAAGCTGCCAAAGCGCGCGGTATCGACATCGTGTTGGCCGACACCGCAGG
CCGCCTGCCGACCCAGCTTCATTTGATGGAAGAAATCAAAAAAGTGAAGCGCGTGCTGCAAAAATCCATGCCCGAAGCGC
CGCATGAAATTATTGTGGTGTTGGATGCGAATATCGGCCAAAACGCCATTAATCAGGTGGTGGCGTTTGATGACGCGCTC
GATGTTACCGGCCTGATTGTTACCAAACTCGACGGTACGGCCAAAGGCGGCATTCTGGCTGCGCTGGCTTCCAACCGCCC
GATTCCCGTTCGCTATATCGGCGTGGGCGAGAGCATCGACGACTTGCGCCCGTTTGACGCGCGTGCGTTTGTGGATGCTT
TGTTTGATTAA

Domains

Predicted by InterproScan.

SRP54-type protein, GTPase domain (SRP54)

(256-455)

SRP54-type protein, helical bundle domain (SRP54_N)

(171-236)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A448UE49

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilA Neisseria gonorrhoeae MS11

69.651

100

0.7

Multiple sequence alignment