Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Machinery gene
Locus tag   EL276_RS04770 Genome accession   NZ_LR134516
Coordinates   1039549..1041780 (-) Length   743 a.a.
NCBI ID   WP_126304558.1    Uniprot ID   A0A3S4ZC30
Organism   Neisseria animaloris strain NCTC12227     
Function   DNA processing; DNA transport into the cytoplasm (predicted from homology)   
DNA processing DNA binding and uptake

Genomic Context

Location: 1034549..1046780
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL276_RS04755 (NCTC12227_00962) - 1037155..1037514 (+) 360 WP_085389726.1 hypothetical protein -
  EL276_RS04760 (NCTC12227_00963) - 1037581..1038552 (+) 972 WP_126304556.1 class 1 fructose-bisphosphatase -
  EL276_RS04765 (NCTC12227_00964) - 1038669..1039403 (+) 735 WP_107879071.1 ankyrin repeat domain-containing protein -
  EL276_RS04770 (NCTC12227_00965) comA 1039549..1041780 (-) 2232 WP_126304558.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  EL276_RS04775 (NCTC12227_00966) - 1041985..1043061 (+) 1077 WP_107879069.1 sulfate ABC transporter substrate-binding protein -
  EL276_RS04780 (NCTC12227_00967) - 1043168..1043506 (-) 339 WP_054598602.1 P-II family nitrogen regulator -

Sequence

Protein


Download         Length: 743 a.a.        Molecular weight: 81499.59 Da        Isoelectric Point: 10.1042

>NTDB_id=1123726 EL276_RS04770 WP_126304558.1 1039549..1041780(-) (comA) [Neisseria animaloris strain NCTC12227]
MPRFWLPLWVSGVVVSFALPAVPSWTVLAAVWLCLFAAAWRFRAAAWLLIAFSGALYGIWRTQSALEQQWPAVQTASVPL
TIEVADLPQRDDKRVRFTARARDDAGREYRLLLSDYGLRDWPVGSRWQVKARVRPPVGEVNLRGFNREAWALADSIGGVG
SIGKERQPLPENRAGVLLRVREAVSLRWRQTDTGGRDFSDGIGLMRALSIGEQSALSAQSWQAFRPLGLNHLVSISGLHV
GMVAVLAGWLTKQLLRLLPRVPKRPRVWMLAAGLAAALFYAGLAGFSVPTQRSVLMLCALAWAWWRGSGASVWAGWWQAL
AWVLLFDPLAVLSAGFWLSFGLVGALLWVSAGRLNERGWLLAVRGQWAVSLLSVAALGSMFASLPLISPLVNALAIPWFS
WMLVPLALLASLLPFGWLQWLAAAAGEYTMRVLVWVAEYAPEYAVAASPPYLLPLAVLAVLMVLLPRGTGWKPLAWLVLA
GFVLYRPPPVVEGRLKVTVWDAGQGLSVLMQTKNHHLLFDTGTEHIANAQILPALNAAGVRRLDALVLSHHDADHDGGFA
EISRSKQPRRIWAGQPEFYQGAEFCGERQWQWDGTVFEFLRPSENLKTADDNEQSCVLRVLAGGQSLLVTGDLGKRGELA
LVEKYGEGLYSQVLVLGHHGSDTSSAGGFLNAVAPQYAVASSGYANAYKHPAAAVQNRVKAHGIELLRTDLSGALVFELG
AGEEVRAGRLKTIKPYWQRKPFE

Nucleotide


Download         Length: 2232 bp        

>NTDB_id=1123726 EL276_RS04770 WP_126304558.1 1039549..1041780(-) (comA) [Neisseria animaloris strain NCTC12227]
ATGCCCCGTTTCTGGCTGCCGCTTTGGGTAAGCGGCGTTGTTGTTTCGTTTGCGCTGCCCGCCGTGCCGTCTTGGACGGT
GCTGGCGGCGGTATGGCTGTGCCTGTTTGCAGCGGCGTGGCGGTTTCGGGCGGCGGCTTGGCTGCTGATCGCCTTTTCCG
GCGCGTTATACGGCATCTGGCGCACGCAGTCTGCTTTGGAACAACAATGGCCTGCGGTTCAGACGGCCTCTGTGCCGCTC
ACGATAGAAGTGGCGGATTTGCCGCAGCGCGACGACAAACGGGTGCGTTTTACGGCGCGGGCGCGTGATGATGCGGGGCG
GGAATACCGTTTGCTGCTGTCGGATTACGGCCTGCGCGATTGGCCGGTCGGCAGCCGCTGGCAGGTTAAGGCGCGGGTTA
GGCCGCCGGTAGGCGAGGTTAATCTGCGCGGTTTCAACCGTGAGGCGTGGGCGTTGGCCGACAGCATCGGCGGGGTGGGC
AGCATCGGCAAGGAAAGGCAGCCGTTGCCGGAAAACCGTGCCGGTGTGTTGTTGCGTGTGCGCGAAGCGGTGAGCCTGCG
CTGGCGGCAAACCGATACCGGCGGGCGGGATTTTTCAGACGGCATCGGTTTGATGCGGGCATTGAGCATAGGCGAGCAGT
CGGCTTTGAGCGCACAATCTTGGCAGGCATTCCGGCCTTTGGGCCTGAACCATTTGGTGAGTATTTCCGGCCTGCATGTG
GGTATGGTGGCGGTGCTGGCGGGGTGGCTGACGAAGCAGTTGCTGCGTCTGCTGCCGCGCGTACCGAAACGGCCACGGGT
GTGGATGTTGGCGGCGGGTTTGGCTGCGGCGTTGTTTTATGCGGGTTTGGCGGGGTTTTCGGTGCCGACGCAGCGCAGCG
TTTTGATGCTGTGTGCGCTGGCGTGGGCTTGGTGGCGCGGCAGCGGTGCGTCGGTATGGGCGGGCTGGTGGCAGGCGTTG
GCTTGGGTGCTGCTGTTTGACCCGTTGGCGGTATTGAGCGCGGGGTTTTGGCTCTCGTTCGGCTTGGTGGGTGCTTTGCT
GTGGGTGTCGGCAGGCCGTCTGAACGAACGCGGTTGGCTGTTGGCGGTGCGCGGGCAATGGGCGGTGTCGCTGTTGTCGG
TGGCGGCCTTGGGCAGCATGTTTGCTTCGCTGCCGCTCATCAGCCCGTTGGTGAATGCGTTGGCGATTCCGTGGTTTTCG
TGGATGCTGGTGCCGCTGGCTCTGCTGGCTTCGCTGCTGCCGTTTGGTTGGCTGCAATGGCTGGCGGCCGCAGCGGGCGA
ATACACCATGCGCGTGTTGGTTTGGGTGGCGGAATATGCACCCGAATATGCGGTGGCGGCCTCGCCGCCTTATCTGCTGC
CGTTGGCGGTGCTGGCGGTATTGATGGTGCTGCTGCCGCGCGGCACGGGCTGGAAACCGCTGGCGTGGCTGGTGTTGGCG
GGGTTTGTGCTGTACCGCCCGCCGCCTGTTGTGGAAGGCCGTCTGAAAGTAACGGTGTGGGACGCGGGGCAAGGTTTGTC
AGTATTGATGCAGACGAAAAACCATCATCTGCTGTTCGACACCGGTACGGAACACATCGCCAACGCGCAGATTCTGCCTG
CGCTGAATGCCGCCGGTGTACGCCGTTTGGATGCACTGGTGCTGTCGCATCACGATGCCGACCACGACGGCGGATTTGCC
GAAATCAGCCGCTCGAAACAGCCGCGCCGAATCTGGGCGGGGCAGCCTGAGTTTTATCAAGGTGCGGAGTTTTGCGGGGA
GCGGCAATGGCAATGGGACGGCACGGTGTTTGAGTTTTTAAGGCCGTCTGAAAATCTGAAAACGGCCGACGACAACGAGC
AAAGCTGCGTTCTGCGCGTGCTGGCGGGCGGGCAGTCGCTGCTGGTAACGGGCGATTTGGGCAAACGCGGCGAGCTGGCG
TTGGTGGAAAAATACGGCGAAGGTTTGTACAGCCAAGTGCTGGTGTTGGGGCATCACGGCAGCGACACTTCGTCGGCGGG
CGGTTTTCTGAATGCCGTTGCACCGCAATACGCCGTGGCTTCGAGCGGTTATGCCAACGCCTACAAACACCCCGCCGCTG
CGGTGCAAAACCGCGTAAAAGCCCACGGTATCGAACTGCTGCGTACCGATTTGTCGGGCGCGCTGGTGTTTGAACTAGGA
GCGGGGGAAGAAGTGCGGGCAGGCCGTCTGAAAACAATTAAACCGTATTGGCAGAGAAAGCCGTTTGAATGA

Domains

Predicted by InterproScan.

Domain of unknown function (DUF4131) (DUF4131)

(23-163)

Competence protein (Competence)

(208-465)

Metallo-beta-lactamase superfamily (Lactamase_B)

(501-666)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A3S4ZC30

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Neisseria gonorrhoeae MS11

63.833

99.731

0.637

Multiple sequence alignment