Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpC   Type   Regulator
Locus tag   EL254_RS09215 Genome accession   NZ_LR134512
Coordinates   1768811..1771258 (-) Length   815 a.a.
NCBI ID   WP_000020285.1    Uniprot ID   -
Organism   Streptococcus agalactiae strain NCTC13949     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1763811..1776258
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL254_RS09190 (NCTC13949_01814) - 1764092..1765348 (+) 1257 WP_001285395.1 toxic anion resistance protein -
  EL254_RS09195 (NCTC13949_01815) hslO 1765488..1766363 (+) 876 WP_000357828.1 Hsp33 family molecular chaperone HslO -
  EL254_RS09200 (NCTC13949_01816) dusB 1766347..1767324 (+) 978 WP_000192733.1 tRNA dihydrouridine synthase DusB -
  EL254_RS09205 (NCTC13949_01817) - 1767445..1768086 (+) 642 WP_000909523.1 deoxynucleoside kinase -
  EL254_RS09210 (NCTC13949_01818) - 1768100..1768591 (+) 492 WP_000586898.1 GNAT family N-acetyltransferase -
  EL254_RS09215 (NCTC13949_01819) clpC 1768811..1771258 (-) 2448 WP_000020285.1 ATP-dependent Clp protease ATP-binding subunit Regulator
  EL254_RS09220 (NCTC13949_01820) - 1771255..1771719 (-) 465 WP_000985641.1 CtsR family transcriptional regulator -
  EL254_RS09225 (NCTC13949_01821) - 1771892..1772353 (+) 462 WP_001106578.1 COG2426 family protein -
  EL254_RS09230 (NCTC13949_01822) tsf 1772513..1773553 (-) 1041 WP_000808080.1 translation elongation factor Ts -
  EL254_RS09235 (NCTC13949_01823) rpsB 1773647..1774417 (-) 771 WP_000268453.1 30S ribosomal protein S2 -
  EL254_RS09240 (NCTC13949_01824) ahpC 1774694..1775254 (+) 561 WP_000060538.1 alkyl hydroperoxide reductase subunit C -

Sequence

Protein


Download         Length: 815 a.a.        Molecular weight: 90626.08 Da        Isoelectric Point: 5.8782

>NTDB_id=1123641 EL254_RS09215 WP_000020285.1 1768811..1771258(-) (clpC) [Streptococcus agalactiae strain NCTC13949]
MSHYSIKLQEVFRLAQFQAARYESHYLESWHLLLAMVLVHDSVAGLTFAEYESEVAIEEYEAATILALGRAPKEEITDYQ
FLEQSSALKKILKLAENISIVVGAEDVGTEHVLLAMLVNKDLLATRILELVGFRGQDDGESVRMVDLRKALERHAGFTKD
DIKAIYELRNPKKAKSGASFSDMMKPPSTAGDLADFTRDLSQMTVDGEIEPVIGRDTEISRMVQVLSRKTKNNPVLVGDA
GVGKTALAYGLAQRIANGNIPYELRDMRVLELDMMSVVAGTRFRGDFEERMNQIIADIEEDGHIILFIDELHTIMGSGSG
IDSTLDAANILKPALARGTLRTVGATTQEEYQKHIEKDAALSRRFAKVLVEEPNLEDAYEILLGLKPAYEAFHNVTISDE
AVMTAVKVAHRYLTSKNLPDSAIDLLDEASATVQMMIKKNAPSLLTEVDQAILDDDMKSASKALKASHKDKKRKPIAVTE
DHIMATLSRLSGIPVEKLTQADSKKYLNLEKELHKRVIGQDDAVTAISRAIRRNQSGIRTGKRPIGSFMFLGPTGVGKTE
LAKALAEVLFDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYDEGGELTEKVRNKPYSVLLFDEVEKAHPDIFNVLLQV
LDDGVLTDSRGRKVDFSNTIIIMTSNLGATALRDDKTVGFGAKDISHDYTAMQKRIMEELKKAYRPEFINRIDEKVVFHS
LSQDNMREVVKIMVKPLILALKDKGMDLKFQPSALKHLAEDGYDIEMGARPLRRTIQTQVEDHLSELLLANQVKEGQVIK
IGVSKGKLKFDIAKS

Nucleotide


Download         Length: 2448 bp        

>NTDB_id=1123641 EL254_RS09215 WP_000020285.1 1768811..1771258(-) (clpC) [Streptococcus agalactiae strain NCTC13949]
ATGAGTCATTATTCCATAAAATTACAAGAAGTATTCAGATTGGCGCAATTTCAAGCAGCACGCTATGAAAGTCACTATTT
AGAAAGCTGGCATCTTCTTTTAGCAATGGTTTTAGTTCATGATTCAGTAGCTGGTTTGACATTTGCTGAATATGAGTCTG
AAGTTGCAATTGAAGAGTACGAAGCAGCAACAATTTTAGCTTTAGGTAGAGCACCGAAAGAAGAGATTACCGATTATCAA
TTTTTAGAGCAATCATCGGCTTTGAAAAAGATCTTAAAGTTAGCAGAAAATATTAGTATCGTAGTAGGAGCTGAAGATGT
GGGTACTGAACATGTCTTGCTTGCTATGTTGGTTAATAAAGATTTATTAGCCACACGTATCTTAGAATTAGTTGGTTTTA
GAGGTCAAGACGATGGTGAATCAGTTCGTATGGTTGATTTACGTAAGGCTCTAGAACGTCATGCCGGTTTTACAAAAGAT
GATATCAAAGCAATTTATGAATTACGTAATCCTAAAAAAGCAAAGTCGGGTGCTTCTTTTTCTGATATGATGAAACCACC
GAGTACTGCTGGTGATTTAGCTGATTTCACACGTGATTTATCACAGATGACGGTTGATGGGGAAATTGAACCTGTTATTG
GGCGTGATACAGAAATTTCACGTATGGTCCAAGTCTTAAGTCGTAAAACAAAGAATAATCCTGTCTTAGTTGGAGATGCG
GGTGTCGGTAAAACAGCTTTGGCGTACGGTCTAGCACAACGTATTGCTAATGGAAATATTCCTTATGAGCTTAGAGATAT
GCGTGTTCTAGAGTTAGATATGATGAGCGTTGTTGCTGGAACTCGTTTTCGTGGTGATTTTGAGGAACGTATGAATCAAA
TCATTGCAGATATTGAAGAAGACGGTCATATTATTCTTTTCATTGATGAACTGCATACTATTATGGGTTCTGGCTCTGGT
ATTGATAGCACACTTGATGCTGCTAATATTTTAAAACCAGCTTTGGCCCGAGGCACTTTACGCACTGTTGGAGCAACAAC
TCAAGAGGAATATCAAAAGCATATTGAAAAAGATGCTGCTTTATCTCGTCGCTTTGCAAAAGTTTTAGTAGAAGAACCAA
ATCTTGAAGACGCTTATGAAATTCTACTTGGATTGAAGCCAGCGTATGAAGCCTTTCATAATGTTACTATTTCAGATGAA
GCAGTTATGACTGCTGTAAAAGTGGCTCATCGTTATTTGACAAGTAAGAATTTACCAGACTCAGCTATAGACTTACTTGA
TGAAGCTTCTGCCACTGTGCAAATGATGATTAAGAAAAATGCTCCTTCGCTTTTAACAGAAGTTGACCAAGCTATTTTAG
ATGATGATATGAAATCTGCTTCTAAAGCTCTAAAAGCAAGCCATAAGGATAAAAAGCGTAAGCCTATTGCCGTAACCGAA
GATCATATTATGGCAACTCTCAGCCGTCTATCTGGTATTCCTGTTGAAAAATTGACACAAGCTGATAGTAAAAAATACCT
CAATTTAGAAAAAGAATTGCATAAACGTGTTATCGGTCAAGATGATGCAGTTACCGCCATTAGTCGTGCTATCCGTCGCA
ATCAATCTGGCATTCGTACTGGTAAGCGTCCTATTGGTTCCTTTATGTTCTTGGGACCAACTGGTGTTGGTAAGACAGAG
TTAGCAAAAGCCTTGGCAGAAGTGTTGTTTGATGATGAATCAGCCCTAATTCGTTTTGATATGTCGGAATATATGGAAAA
ATTCGCAGCTTCTCGCCTGAATGGGGCACCTCCAGGTTATGTTGGTTATGATGAAGGAGGAGAGCTGACTGAAAAAGTAC
GCAATAAACCATATTCAGTTTTACTTTTTGATGAAGTTGAAAAAGCTCATCCAGATATTTTTAATGTATTATTACAAGTG
CTTGATGATGGCGTTTTAACAGATAGTCGAGGACGAAAAGTTGATTTTTCAAATACTATAATCATTATGACTTCTAATTT
AGGAGCAACTGCATTACGTGACGATAAAACAGTTGGTTTTGGAGCTAAGGATATCAGCCATGATTATACTGCTATGCAAA
AACGTATTATGGAGGAGCTTAAAAAAGCTTATCGACCAGAATTTATCAATCGTATTGATGAGAAAGTTGTATTCCATAGT
CTCAGTCAAGATAATATGCGTGAAGTTGTGAAAATTATGGTTAAACCTTTAATTTTAGCGCTTAAAGATAAAGGTATGGA
TCTGAAATTCCAGCCTTCAGCCTTGAAACACTTGGCAGAGGATGGCTATGATATAGAAATGGGTGCTCGTCCACTGCGTA
GAACTATTCAAACGCAAGTAGAGGATCATTTATCAGAACTACTATTGGCAAATCAAGTGAAAGAGGGGCAAGTAATTAAG
ATTGGCGTATCCAAAGGCAAATTGAAATTTGATATTGCAAAATCATAA

Domains

Predicted by InterproScan.

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(721-801)

ATPase family associated with various cellular activities (AAA) (AAA)

(235-367)

AAA lid domain (AAA_lid_9)

(375-471)

AAA domain (Cdc48 subfamily) (AAA_2)

(543-714)

Clp amino terminal domain, pathogenicity island component (Clp_N)

(105-132)

Clp amino terminal domain, pathogenicity island component (Clp_N)

(15-46)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpC Streptococcus mutans UA159

76.478

99.632

0.762
  clpC Streptococcus thermophilus LMG 18311

72.583

100

0.728
  clpC Streptococcus thermophilus LMD-9

72.46

100

0.726
  clpC Streptococcus pneumoniae Rx1

68.428

99.877

0.683
  clpC Streptococcus pneumoniae D39

68.428

99.877

0.683
  clpC Streptococcus pneumoniae TIGR4

68.428

99.877

0.683
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

48.438

100

0.494
  clpC Bacillus subtilis subsp. subtilis str. 168

45.204

100

0.463
  clpE Streptococcus mutans UA159

46.238

78.282

0.362

Multiple sequence alignment