Detailed information NTG1123616

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: EL254_RS02740
• Genome accession: NZ_LR134512
• Coordinates: 466557..467630 (+)
• Length: 357 a.a.
• NCBI ID: WP_000790651.1
• Uniprot ID: A0AAW6XPT9
• Organism: Streptococcus agalactiae strain NCTC13949
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 461557..472630

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EL254_RS02705 (NCTC13949_00530)	-	462448..463512 (+)	1065	WP_000021293.1	MmcQ/YjbR family DNA-binding protein	-
EL254_RS02710 (NCTC13949_00531)	asnA	463627..464619 (+)	993	WP_000748015.1	aspartate--ammonia ligase	-
EL254_RS02715 (NCTC13949_00532)	-	464664..465113 (-)	450	WP_000592261.1	hypothetical protein	-
EL254_RS02725 (NCTC13949_00533)	rsmD	465244..465783 (+)	540	WP_001266830.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
EL254_RS02730 (NCTC13949_00534)	-	465795..466085 (+)	291	WP_000384889.1	hypothetical protein	-
EL254_RS02735 (NCTC13949_00535)	coaD	466082..466567 (+)	486	WP_000161894.1	pantetheine-phosphate adenylyltransferase	-
EL254_RS02740 (NCTC13949_00536)	sepM	466557..467630 (+)	1074	WP_000790651.1	SepM family pheromone-processing serine protease	Regulator
EL254_RS02745 (NCTC13949_00537)	-	467705..469039 (+)	1335	WP_000137518.1	bifunctional metallophosphatase/5'-nucleotidase	-
EL254_RS02750 (NCTC13949_00538)	-	469108..469686 (+)	579	WP_001224500.1	YutD family protein	-
EL254_RS02755 (NCTC13949_00539)	rlmN	469737..470843 (+)	1107	WP_000039434.1	23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN	-
EL254_RS02760 (NCTC13949_00540)	-	470843..471358 (+)	516	WP_000919803.1	VanZ family protein	-

Sequence

Protein

• Length: 357 a.a.
• Molecular weight: 39131.31 Da
• Isoelectric Point: 10.4286

>NTDB_id=1123616 EL254_RS02740 WP_000790651.1 466557..467630(+) (sepM) [Streptococcus agalactiae strain NCTC13949]
MKNKDPKRKHKSLLGLLKWWIIGFAFLLLVLASLVVRLPYYLEMPGGAYDIRSVLKVNKKADKAKGSYNFVAVSVSQATP
AQVLYAWLTPFTELSSKEETTGGFSNDDYLRINQFYMETSQNESVYQALKLANKQVSLTYKGVYVLNLAKNSTFKDRLHL
ADTVTGVNGKSFKNSSQLIKYVAALHLGDKVKVQYTSQGKKKESVGKVIKLSNGKNGIGIGLTDHTEVSSDVPVDFNTEG
VGGPSAGLMFTLAIYDQLVKEDLRKGRKIAGTGTIEQNGHVGDIGGAGLKVVSAAKKGMDIFFVPNNPIDKNAKKGKTKV
QTNYQEAKAAAKRLGTKMKIVPVQNVQQAIDYLKKTK

Nucleotide

• Length: 1074 bp

>NTDB_id=1123616 EL254_RS02740 WP_000790651.1 466557..467630(+) (sepM) [Streptococcus agalactiae strain NCTC13949]
GTGAAGAATAAAGATCCAAAAAGAAAACATAAAAGTTTACTAGGTCTGCTTAAATGGTGGATTATAGGTTTTGCTTTTTT
ATTGTTAGTATTAGCAAGCCTTGTGGTGAGGCTACCTTATTATTTGGAAATGCCAGGTGGAGCTTATGATATCCGTTCGG
TATTGAAAGTGAATAAAAAGGCTGATAAAGCTAAGGGTTCGTACAATTTTGTAGCGGTTTCTGTCAGTCAAGCAACGCCA
GCTCAGGTTCTTTATGCTTGGTTAACTCCTTTTACAGAATTATCTAGTAAAGAGGAGACAACAGGTGGCTTTAGTAATGA
CGATTATCTCAGAATTAATCAATTCTACATGGAGACTTCTCAAAATGAGTCCGTCTATCAAGCTTTAAAGTTAGCTAATA
AGCAAGTATCTCTTACTTATAAAGGAGTTTATGTGCTTAACTTAGCTAAAAATTCGACATTTAAAGATAGATTACATTTA
GCTGATACAGTCACAGGAGTTAATGGCAAAAGTTTCAAAAATTCTTCTCAACTTATCAAATATGTTGCAGCTCTTCATCT
AGGTGATAAAGTAAAGGTACAATACACAAGTCAAGGTAAAAAGAAAGAATCGGTTGGTAAAGTTATTAAACTATCAAACG
GTAAAAATGGTATTGGTATCGGTTTGACAGACCATACAGAAGTATCATCTGATGTTCCTGTGGACTTTAATACTGAAGGT
GTTGGAGGACCAAGTGCAGGTTTAATGTTTACTTTAGCGATTTACGACCAATTGGTTAAAGAAGATTTACGTAAAGGACG
TAAGATTGCAGGTACTGGTACTATTGAGCAAAATGGGCATGTTGGCGATATTGGTGGAGCAGGTTTGAAAGTTGTTTCAG
CGGCTAAAAAAGGAATGGATATTTTCTTTGTTCCTAATAATCCGATCGATAAAAATGCTAAAAAAGGCAAAACAAAGGTT
CAGACGAATTATCAAGAGGCAAAAGCAGCAGCTAAGCGATTAGGTACGAAGATGAAAATTGTACCAGTTCAAAATGTTCA
GCAAGCTATTGATTATTTGAAAAAAACAAAATAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (137-203)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (241-307)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	69.027	94.958	0.655