Detailed information NTG1122616

Bioinformatically predicted

Overview

• Name: comEC
• Type: Machinery gene
• Locus tag: EL220_RS05480
• Genome accession: NZ_LR134388
• Coordinates: 1220905..1223127 (-)
• Length: 740 a.a.
• NCBI ID: WP_027271728.1
• Uniprot ID: A0A0W0YPW9
• Organism: Legionella sainthelensi strain NCTC11988
• Function: ssDNA transport through the inner membrane (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1215905..1228127

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EL220_RS19630 (NCTC11988_01139)	cydP	1216054..1216224 (-)	171	WP_330987400.1	cytochrome oxidase putative small subunit CydP	-
EL220_RS05450 (NCTC11988_01140)	-	1216218..1216652 (-)	435	WP_232002640.1	group III truncated hemoglobin	-
EL220_RS05455 (NCTC11988_01141)	-	1216907..1217230 (+)	324	WP_027271723.1	hypothetical protein	-
EL220_RS05460 (NCTC11988_01142)	-	1217433..1218251 (+)	819	WP_027271724.1	mechanosensitive ion channel family protein	-
EL220_RS05465 (NCTC11988_01143)	-	1218350..1218919 (-)	570	WP_027271725.1	hypothetical protein	-
EL220_RS05470 (NCTC11988_01144)	-	1219170..1219400 (+)	231	WP_027271726.1	hypothetical protein	-
EL220_RS05475 (NCTC11988_01145)	-	1219737..1220795 (-)	1059	WP_027271727.1	bifunctional transcriptional activator/DNA repair enzyme AdaA	-
EL220_RS05480 (NCTC11988_01146)	comEC	1220905..1223127 (-)	2223	WP_027271728.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
EL220_RS05485 (NCTC11988_01147)	potA	1223402..1224496 (+)	1095	WP_027271729.1	spermidine/putrescine ABC transporter ATP-binding protein PotA	-
EL220_RS05490 (NCTC11988_01148)	-	1224486..1225310 (+)	825	WP_027271730.1	ABC transporter permease	-
EL220_RS05495 (NCTC11988_01149)	-	1225495..1226073 (+)	579	WP_232002641.1	ABC transporter permease subunit	-
EL220_RS05500 (NCTC11988_01150)	-	1226070..1227095 (+)	1026	WP_027271732.1	ABC transporter substrate-binding protein	-
EL220_RS05505 (NCTC11988_01151)	-	1227343..1227981 (+)	639	WP_027271733.1	hypothetical protein	-

Sequence

Protein

• Length: 740 a.a.
• Molecular weight: 83680.67 Da
• Isoelectric Point: 9.6896

>NTDB_id=1122616 EL220_RS05480 WP_027271728.1 1220905..1223127(-) (comEC) [Legionella sainthelensi strain NCTC11988]
MEVFCFFIGILYRYTLHGFLPVIIFLICFIIPKYTNILFFLLGVLTASLHQSQNLPKGIPDVEVIPQASIEGTIASIPVQ
GSSKTLFVLALEQYDHHPAQGIIQLVWYNKAPKIHAGQRWAFNVKLKKPRNYLNPGSMDYVRSLTTRHIAWTGYIHSRGN
KLLQKSSSSFNWLELREQLSDQLNLLAPDQQTAGIIEALALNITTHIAPKSWDLFRRTGTTHLFGISGEHIALISGIVYW
LLRWLWTRNSRLCLYIPAPYIASIGGLLAALGYAFLAGFAPPVQRALIGCFFYTLYSLGHQRFTAWQVWRYALCGVLWIE
PHAVFMQGFYFSFLAVACLLLTQQRWRFKGYKASLVLQLSCLIGLMPLTLYWYAYGSINGFIANLFAIPLVGLLIVPLSL
MTMTVSSLSIAKILMKPLSLLISLLFKGLSLTEHLAAVNINCSLYSMEMAIVLIGALLMWVLLPIRSFQWIAMLWLLLPF
FPPRTMLQSGEAKIDVLDVGQGLAVAIRTQRHVLLYDTGDRFFQGNDLGKMVILPYLKALGIKKVDMIVVSHPDKDHRGG
LNSLEREMQVDRLLVNDPHFYHRGLKCHDYPPWQWDGISFRFLPIKTHFTGKNNSSCILQIETHAGRMLLTGDIEKIAED
YLVQTYGNKLKSDVLVVPHHGSKTSSSYRFLLEVAPIYAIASLGFDNRFHFPHAKTLANMKNLSIPFYRTDICGMVQITL
PVQGSINKPICFSGQRLQPV

Nucleotide

• Length: 2223 bp

>NTDB_id=1122616 EL220_RS05480 WP_027271728.1 1220905..1223127(-) (comEC) [Legionella sainthelensi strain NCTC11988]
ATGGAAGTTTTTTGCTTTTTTATAGGCATATTATATCGATATACCTTGCACGGATTTTTGCCTGTAATTATTTTTTTGAT
TTGTTTCATTATTCCTAAGTACACGAATATTCTGTTTTTTCTTTTAGGTGTCCTCACCGCCTCTCTGCATCAATCACAAA
ATTTACCTAAAGGAATACCTGATGTAGAGGTAATACCTCAAGCGAGTATAGAAGGAACCATTGCATCAATACCAGTCCAA
GGCTCATCCAAGACACTTTTTGTATTAGCTTTAGAACAATACGACCACCATCCGGCCCAAGGGATAATCCAATTAGTATG
GTACAACAAAGCCCCTAAAATTCATGCAGGACAACGATGGGCATTTAATGTGAAATTAAAAAAGCCGAGAAATTATCTTA
ATCCAGGGAGTATGGATTATGTGCGTTCACTCACAACTCGTCATATTGCCTGGACTGGATATATTCATTCCAGAGGCAAT
AAGTTACTGCAAAAATCCTCTTCATCTTTTAATTGGCTAGAACTAAGGGAACAATTAAGTGATCAACTTAACTTATTAGC
ACCTGATCAACAAACCGCTGGGATTATAGAAGCATTGGCGTTAAATATAACAACCCATATTGCCCCCAAAAGCTGGGATT
TATTTAGACGTACTGGCACAACCCATTTATTTGGTATTTCAGGTGAGCATATCGCCTTAATTTCTGGCATTGTTTATTGG
TTACTGCGTTGGTTATGGACTCGAAACTCTCGTCTTTGTTTATATATTCCAGCCCCTTATATTGCAAGTATCGGTGGTCT
TTTAGCTGCTTTAGGATATGCTTTTTTAGCAGGATTTGCTCCTCCTGTTCAAAGAGCTCTTATAGGATGTTTTTTTTATA
CACTCTATAGTTTGGGTCACCAGCGTTTTACTGCTTGGCAAGTATGGCGATATGCTCTATGTGGTGTTTTATGGATTGAA
CCACATGCAGTATTTATGCAAGGATTCTACTTTTCTTTTCTTGCTGTAGCATGCTTGCTCTTAACGCAACAACGTTGGCG
CTTCAAAGGATATAAAGCTTCTTTAGTCTTACAGTTAAGCTGTTTAATTGGGTTAATGCCCCTAACCTTATATTGGTATG
CTTATGGTTCCATTAATGGATTTATTGCGAACCTATTCGCAATACCTTTGGTGGGATTACTCATCGTCCCCTTATCATTA
ATGACTATGACCGTCAGTTCCTTAAGTATTGCAAAGATACTGATGAAACCCCTTTCCTTGCTCATTTCATTATTGTTTAA
AGGGCTCTCGCTGACAGAACATTTAGCTGCAGTCAATATTAATTGTTCCCTTTACTCTATGGAGATGGCGATTGTGCTAA
TAGGAGCTTTATTGATGTGGGTTTTATTACCCATTAGATCTTTTCAATGGATAGCCATGCTTTGGCTACTGCTTCCATTT
TTTCCACCACGAACAATGCTCCAATCAGGTGAAGCCAAAATCGATGTTTTAGATGTGGGACAAGGCTTGGCTGTTGCAAT
TCGAACACAGCGCCATGTTTTGCTTTATGATACAGGAGATCGCTTTTTTCAAGGAAATGATTTAGGAAAAATGGTTATCT
TGCCTTATCTTAAAGCCCTGGGCATCAAAAAAGTGGATATGATAGTTGTAAGTCATCCTGATAAAGATCATCGTGGGGGA
CTTAATTCACTGGAGAGAGAAATGCAAGTAGACAGACTATTGGTCAATGACCCTCATTTCTACCACCGTGGTTTAAAATG
TCATGATTATCCACCATGGCAATGGGATGGGATCTCGTTCCGTTTCTTGCCAATTAAAACTCATTTTACAGGAAAGAACA
ACAGCTCTTGTATTCTACAAATCGAAACACATGCTGGACGTATGCTCTTAACGGGTGATATTGAAAAAATAGCCGAAGAT
TATTTAGTGCAAACTTATGGTAATAAGCTTAAATCAGATGTACTAGTTGTCCCTCATCATGGCAGCAAAACATCGTCATC
CTATAGATTTTTATTAGAAGTTGCTCCGATTTATGCTATAGCCTCCTTGGGTTTTGATAATCGTTTTCACTTCCCTCATG
CTAAGACTTTAGCAAACATGAAAAATTTGAGTATCCCTTTTTACAGAACAGATATCTGTGGCATGGTGCAAATTACTTTA
CCTGTCCAAGGATCAATCAATAAGCCCATTTGCTTTAGTGGACAGCGGTTGCAACCCGTGTAA

Domains

Predicted by InterproScan.

• Competence protein (Competence) (201-463)

• Domain of unknown function (DUF4131) (DUF4131) (18-157)

• Metallo-beta-lactamase superfamily (Lactamase_B) (498-671)

3D structure

• AlphaFold DB: A0A0W0YPW9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC	Legionella pneumophila strain Lp02	64.169	99.189	0.636
comEC	Legionella pneumophila strain ERS1305867	63.537	99.324	0.631