Detailed information NTG1122154

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: EL160_RS09335
• Genome accession: NZ_LR134351
• Coordinates: 1777625..1778668 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain NCTC13811
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1772625..1783668

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EL160_RS09305 (NCTC13811_01777)	-	1773046..1774302 (-)	1257	WP_001793983.1	aminopeptidase	-
EL160_RS09310 (NCTC13811_01778)	-	1774305..1774505 (-)	201	WP_000180460.1	DUF1128 family protein	-
EL160_RS09315 (NCTC13811_01779)	-	1774652..1775116 (+)	465	WP_000228670.1	low molecular weight protein-tyrosine-phosphatase	-
EL160_RS09320 (NCTC13811_01780)	-	1775123..1775398 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
EL160_RS09325 (NCTC13811_01781)	-	1775676..1776893 (+)	1218	WP_000037081.1	YihY/virulence factor BrkB family protein	-
EL160_RS09330 (NCTC13811_01782)	vraR	1777006..1777635 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
EL160_RS09335 (NCTC13811_01783)	vraS	1777625..1778668 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
EL160_RS09340 (NCTC13811_01784)	liaF	1778665..1779366 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
EL160_RS09345 (NCTC13811_01785)	-	1779381..1779767 (-)	387	WP_001110178.1	hypothetical protein	-
EL160_RS09350 (NCTC13811_01786)	map	1779984..1780742 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
EL160_RS09365 (NCTC13811_01787)	-	1781442..1782428 (+)	987	WP_001014423.1	FUSC family protein	-
EL160_RS09370 (NCTC13811_01788)	-	1782617..1783030 (-)	414	WP_001643743.1	hypothetical protein	-
EL160_RS09375	-	1783059..1783169 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=1122154 EL160_RS09335 WP_001017131.1 1777625..1778668(-) (vraS) [Staphylococcus aureus strain NCTC13811]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=1122154 EL160_RS09335 WP_001017131.1 1777625..1778668(-) (vraS) [Staphylococcus aureus strain NCTC13811]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGACTT
ATACCATACACTTGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTTTCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGCTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1