Detailed information NTG1122016

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: EL147_RS06500
• Genome accession: NZ_LR134341
• Coordinates: 1327704..1330145 (+)
• Length: 813 a.a.
• NCBI ID: WP_007893741.1
• Uniprot ID: G5K7L4
• Organism: Streptococcus pseudoporcinus strain NCTC13786
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 1322704..1335145

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EL147_RS06475 (NCTC13786_01296)	-	1323090..1324052 (-)	963	WP_007893865.1	ring-cleaving dioxygenase	-
EL147_RS06480 (NCTC13786_01297)	-	1324176..1326245 (-)	2070	WP_007893853.1	sodium:proton antiporter	-
EL147_RS06485 (NCTC13786_01298)	-	1326248..1326517 (-)	270	WP_007893877.1	hypothetical protein	-
EL147_RS06490	-	1326867..1327070 (+)	204	WP_003085753.1	cold-shock protein	-
EL147_RS06495 (NCTC13786_01300)	-	1327243..1327704 (+)	462	WP_007893766.1	CtsR family transcriptional regulator	-
EL147_RS06500 (NCTC13786_01301)	clpC	1327704..1330145 (+)	2442	WP_007893741.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
EL147_RS06505 (NCTC13786_01302)	groES	1330358..1330648 (+)	291	WP_007893891.1	co-chaperone GroES	-
EL147_RS06510 (NCTC13786_01303)	groL	1330688..1332316 (+)	1629	WP_007893807.1	chaperonin GroEL	-

Sequence

Protein

• Length: 813 a.a.
• Molecular weight: 90465.00 Da
• Isoelectric Point: 5.9118

>NTDB_id=1122016 EL147_RS06500 WP_007893741.1 1327704..1330145(+) (clpC) [Streptococcus pseudoporcinus strain NCTC13786]
MIDYSLKMQEIFKQAQYQAARFDSQYLETWHLLLAMVVVNNSLAGLVFNEFDAKVTMEEYEAAAILAMGQTPNDDVKEWT
LKGQSRTLTKILQFSDAIRQVTGAQEVGSEHVLFALLLNPDVMATRLLEMAGFKLRDEGQGDLKISDLRKAIERQAAYSK
ETIKAIYELRKPKKTKAGGTFSDMMKPPSSAGDLSDFTRDLTQMASQGLLEPVIGREKEITRMVQVLSRKTKNNPVLVGD
AGVGKTALAYGLAQRIVEGAIPYELQDMRVLELDMMSVVAGTRFRGDFEERMNQIIDDIEADGKIILFVDELHTIMGSGS
GIDSTLDAANILKPALSRGTLHMVGATTQEEYQKHIEKDAALSRRFAKILIEEPNLEDAYQILLGLKSSYEMYHNVRISD
QAVKVAVKVAHRYLTSKNLPDSAIDLLDEASATVQGLIKKETPSFLSPIDQAILDGNFKEVTSILKANKKTKPSPTPVTE
DDIMATLSRLSGIPLEKISQADSQKYLQLEKELHKRVIGQDEAISAISRAIRRNQSGIRTGKRPIGSFMFLGPTGVGKTE
LAKALAEVLFDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYDEGGELTEKVRNKPYSVLLFDEVEKAHPDIFNVLLQV
LDDGVLTDSRGRKVDFTNTIIIMTSNLGATALRDDKTVGFGARDVSQDHQAMEKRILEELKKAYRPEFINRIDEKVVFHS
LSQEDMQQVVRIMVKPLIAALEEKGITLKFQPSALKYLSEKGYDLEMGARPLRRTIQTEVEDKLSELLLSGQLGSGHKLK
IGLAKGKIKCDIE

Nucleotide

• Length: 2442 bp

>NTDB_id=1122016 EL147_RS06500 WP_007893741.1 1327704..1330145(+) (clpC) [Streptococcus pseudoporcinus strain NCTC13786]
ATGATAGATTATTCACTAAAAATGCAGGAAATTTTCAAGCAGGCTCAATATCAGGCAGCTCGCTTTGATAGCCAATATTT
AGAAACATGGCATCTTCTTTTAGCGATGGTCGTGGTTAACAACTCACTAGCTGGACTTGTTTTCAATGAATTTGACGCTA
AAGTTACTATGGAAGAATATGAAGCGGCAGCTATTTTAGCTATGGGACAAACGCCAAATGATGATGTGAAAGAGTGGACC
TTGAAGGGTCAATCTAGAACCTTAACAAAAATTCTTCAATTTTCAGATGCTATCCGTCAGGTAACAGGTGCTCAGGAAGT
GGGGTCAGAACACGTCCTTTTTGCCCTATTGTTAAATCCTGATGTTATGGCAACTCGTTTACTAGAAATGGCTGGTTTTA
AACTACGGGATGAGGGTCAAGGGGATTTGAAAATCTCTGATTTACGTAAAGCAATTGAGAGGCAAGCTGCTTATAGTAAA
GAGACCATTAAGGCTATTTATGAATTGCGCAAACCTAAAAAAACAAAAGCAGGTGGGACATTCTCAGATATGATGAAACC
GCCAAGTTCAGCAGGTGACCTCTCTGATTTCACGCGTGATTTAACACAAATGGCCAGTCAAGGCCTTTTGGAACCGGTGA
TTGGCCGTGAAAAAGAAATTACTCGAATGGTTCAGGTGCTAAGCCGTAAAACTAAGAATAATCCTGTCTTAGTCGGAGAC
GCGGGTGTTGGGAAAACAGCCTTGGCATATGGTCTAGCTCAACGAATTGTCGAGGGAGCTATTCCTTACGAATTGCAGGA
TATGCGAGTTTTGGAACTAGACATGATGAGTGTGGTTGCAGGAACTCGTTTTCGGGGTGATTTTGAAGAACGAATGAACC
AAATCATAGATGATATTGAAGCAGATGGGAAAATTATTCTGTTTGTTGATGAATTACATACGATTATGGGTTCTGGAAGT
GGTATTGATAGTACTTTAGATGCGGCTAATATTTTAAAACCAGCTTTATCTCGTGGGACACTACATATGGTAGGTGCGAC
GACTCAGGAAGAATACCAAAAACATATTGAAAAAGACGCAGCCTTATCTCGTCGCTTTGCTAAAATTTTAATTGAAGAAC
CAAATCTTGAAGATGCCTACCAAATCCTACTTGGACTAAAATCTTCTTATGAAATGTATCATAATGTTAGAATTTCAGAC
CAAGCTGTTAAAGTGGCAGTTAAGGTTGCACACCGTTATTTAACAAGTAAAAATTTGCCAGATTCAGCAATAGACCTCTT
AGATGAAGCCAGTGCAACGGTCCAAGGGCTCATAAAAAAAGAGACACCCTCCTTTTTAAGTCCTATAGACCAGGCTATCC
TCGATGGCAATTTTAAAGAAGTGACTAGCATATTAAAAGCTAATAAGAAAACGAAGCCTAGCCCAACTCCGGTTACAGAA
GATGACATCATGGCAACTTTAAGTAGATTGTCGGGGATACCACTTGAGAAAATTAGCCAAGCTGATAGTCAAAAATACCT
CCAATTAGAGAAAGAATTACACAAACGGGTTATTGGTCAAGACGAAGCTATTTCAGCTATTTCAAGGGCTATTCGTCGCA
ATCAATCTGGTATCCGAACTGGTAAGCGTCCAATTGGCTCATTTATGTTTCTAGGTCCAACAGGTGTTGGAAAAACAGAG
CTTGCTAAAGCCTTGGCTGAGGTTTTATTTGATGATGAGTCAGCATTAATTCGTTTCGATATGTCAGAATACATGGAGAA
ATTTGCAGCCAGTCGTCTCAATGGTGCCCCTCCAGGATATGTAGGCTATGATGAAGGTGGTGAACTGACAGAAAAAGTAA
GGAATAAACCTTATTCTGTTTTGCTTTTTGATGAAGTTGAAAAAGCTCATCCAGATATTTTCAACGTACTTCTTCAAGTT
TTGGACGATGGGGTACTGACAGACTCTCGTGGTCGAAAAGTTGATTTTACAAATACTATTATTATCATGACCAGTAATTT
AGGTGCGACAGCACTTCGAGATGATAAAACTGTAGGATTTGGTGCTCGAGATGTTAGTCAAGATCACCAAGCTATGGAAA
AACGTATTTTAGAGGAGCTAAAGAAAGCTTATCGTCCTGAATTTATTAATCGTATTGATGAAAAGGTTGTTTTCCACAGC
CTAAGTCAAGAAGATATGCAACAAGTGGTGAGGATTATGGTGAAACCGTTGATTGCTGCCTTAGAAGAAAAAGGAATCAC
TCTCAAATTTCAACCGTCAGCACTTAAATACCTATCTGAGAAAGGCTATGATCTGGAGATGGGAGCTCGTCCACTTCGAA
GAACGATTCAAACAGAAGTTGAGGATAAATTGTCAGAATTACTTCTTTCAGGACAGTTAGGCTCTGGGCATAAATTAAAA
ATTGGTTTAGCCAAAGGCAAAATAAAATGTGACATAGAATAA

Domains

Predicted by InterproScan.

• AAA domain (Cdc48 subfamily) (AAA_2) (543-714)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (721-800)

• AAA lid domain (AAA_lid_9) (376-453)

• ATPase family associated with various cellular activities (AAA) (AAA) (236-368)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (18-51)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (101-134)

3D structure

• AlphaFold DB: G5K7L4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Streptococcus mutans UA159	74.662	100	0.747
clpC	Streptococcus thermophilus LMD-9	72.604	100	0.727
clpC	Streptococcus thermophilus LMG 18311	72.604	100	0.727
clpC	Streptococcus pneumoniae TIGR4	65.56	100	0.656
clpC	Streptococcus pneumoniae Rx1	65.56	100	0.656
clpC	Streptococcus pneumoniae D39	65.56	100	0.656
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	48.144	100	0.494
clpC	Bacillus subtilis subsp. subtilis str. 168	44.765	100	0.458