Detailed information NTG1121995

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: EL147_RS03635
• Genome accession: NZ_LR134341
• Coordinates: 756685..757728 (-)
• Length: 347 a.a.
• NCBI ID: WP_007894008.1
• Uniprot ID: G5K9R7
• Organism: Streptococcus pseudoporcinus strain NCTC13786
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 751685..762728

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EL147_RS03610 (NCTC13786_00723)	-	751758..752702 (-)	945	WP_007893994.1	ABC transporter permease subunit	-
EL147_RS03615 (NCTC13786_00724)	-	752705..754183 (-)	1479	WP_007894029.1	sugar ABC transporter ATP-binding protein	-
EL147_RS03620 (NCTC13786_00725)	rbsD	754199..754597 (-)	399	WP_007894040.1	D-ribose pyranase	-
EL147_RS03625 (NCTC13786_00726)	-	754572..755483 (-)	912	WP_007893981.1	ribokinase	-
EL147_RS03630 (NCTC13786_00727)	-	755476..756459 (-)	984	WP_007894011.1	LacI family DNA-binding transcriptional regulator	-
EL147_RS03635 (NCTC13786_00728)	sepM	756685..757728 (-)	1044	WP_007894008.1	SepM family pheromone-processing serine protease	Regulator
EL147_RS03640 (NCTC13786_00729)	coaD	757715..758206 (-)	492	WP_007893991.1	pantetheine-phosphate adenylyltransferase	-
EL147_RS03645 (NCTC13786_00730)	rsmD	758196..758735 (-)	540	WP_007894025.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
EL147_RS03650 (NCTC13786_00731)	asnA	758838..759830 (-)	993	WP_007894038.1	aspartate--ammonia ligase	-
EL147_RS03655 (NCTC13786_00732)	-	760074..761600 (+)	1527	WP_007895264.1	IS1182 family transposase	-
EL147_RS03660 (NCTC13786_00733)	arcC	761707..762657 (-)	951	WP_007892664.1	carbamate kinase	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 38349.34 Da
• Isoelectric Point: 10.1350

>NTDB_id=1121995 EL147_RS03635 WP_007894008.1 756685..757728(-) (sepM) [Streptococcus pseudoporcinus strain NCTC13786]
MKIIKKVKWWLISILAVVALLFALFFPLPYYIEMPGGAYDIRSVLKVNDKRDKEKGSYNFVAVSLSRATFAQILYAWVTP
FTEISSLENTTGGYSAADYMRINQYYMETSQNGAIYQALQLAGKPVSLDYLGVYVLDVNKESTFRGILNIADTVTGVNQK
EFKSSTELIKYVSSLKRGETVTVQYTSGNEKKSKSGKLIKLKNGKNGIGIGLTDHTKVHTDEKIEFSTEGVGGPSAGLMF
TLDIYDQLNQENLRKGRRIAGTGTIDQDGKVGDIGGAGLKVVAAANEGADIFFVPNNPVDKRIKKVKPNAKTNYKEALEV
AKKIKTKMKIVPVRNVKEAIAYLQKTK

Nucleotide

• Length: 1044 bp

>NTDB_id=1121995 EL147_RS03635 WP_007894008.1 756685..757728(-) (sepM) [Streptococcus pseudoporcinus strain NCTC13786]
ATGAAGATAATTAAAAAAGTCAAATGGTGGTTAATTAGTATTCTGGCAGTAGTTGCCCTCTTGTTTGCCCTCTTTTTCCC
TTTACCTTATTATATTGAGATGCCTGGTGGAGCCTACGATATCCGTTCAGTGCTTAAGGTAAACGATAAAAGGGATAAGG
AGAAAGGCTCTTATAATTTTGTGGCGGTCAGTTTGAGTCGAGCCACTTTTGCTCAAATTCTTTATGCTTGGGTAACGCCA
TTCACAGAGATTTCATCTTTGGAAAATACAACTGGTGGCTATAGTGCGGCAGATTATATGCGCATCAATCAATATTACAT
GGAGACCTCTCAAAACGGAGCTATCTATCAAGCCTTACAATTAGCTGGGAAACCTGTTTCTTTAGACTACCTAGGTGTTT
ATGTTTTGGATGTCAATAAAGAGTCTACTTTTCGTGGTATTCTAAATATTGCTGATACTGTTACAGGAGTCAATCAAAAA
GAATTTAAGAGTTCAACTGAACTTATTAAATACGTTTCAAGTTTGAAACGGGGTGAAACAGTGACGGTGCAATATACCAG
CGGTAATGAGAAAAAATCTAAAAGTGGTAAGCTTATTAAGCTAAAAAATGGAAAGAATGGTATTGGAATTGGCTTAACGG
ACCACACAAAAGTCCATACAGATGAAAAGATTGAGTTTTCGACAGAAGGTGTAGGTGGACCAAGTGCTGGGCTTATGTTT
ACACTGGATATTTATGATCAACTAAATCAAGAAAACCTGCGTAAAGGTCGTCGTATTGCTGGTACTGGAACGATTGATCA
AGATGGCAAAGTTGGTGATATTGGTGGTGCAGGATTAAAAGTTGTTGCTGCAGCTAACGAAGGGGCTGATATTTTCTTTG
TACCCAACAATCCAGTTGATAAACGGATCAAAAAAGTAAAACCAAATGCAAAGACCAATTATAAAGAAGCCTTGGAAGTC
GCTAAAAAAATAAAAACCAAGATGAAAATTGTTCCCGTTAGAAATGTCAAAGAAGCTATTGCTTACTTGCAAAAGACAAA
ATAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (131-193)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (232-340)

3D structure

• AlphaFold DB: G5K9R7

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	71.884	99.424	0.715