Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpE   Type   Regulator
Locus tag   EL147_RS03475 Genome accession   NZ_LR134341
Coordinates   722033..724315 (+) Length   760 a.a.
NCBI ID   WP_007894778.1    Uniprot ID   G5K907
Organism   Streptococcus pseudoporcinus strain NCTC13786     
Function   repress competence development (at the early growth phase) (predicted from homology)   
Competence regulation

Genomic Context

Location: 717033..729315
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL147_RS03445 (NCTC13786_00690) - 717067..717936 (-) 870 WP_007894665.1 polyprenyl synthetase family protein -
  EL147_RS03450 (NCTC13786_00691) - 717936..718154 (-) 219 WP_003084065.1 exodeoxyribonuclease VII small subunit -
  EL147_RS03455 (NCTC13786_00692) xseA 718129..719472 (-) 1344 WP_007894708.1 exodeoxyribonuclease VII large subunit -
  EL147_RS03460 (NCTC13786_00693) - 719618..720451 (-) 834 WP_007894637.1 NAD(P)H-hydrate dehydratase -
  EL147_RS03465 (NCTC13786_00694) - 720448..721302 (-) 855 WP_007894634.1 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase -
  EL147_RS03470 (NCTC13786_00695) - 721524..721754 (-) 231 WP_007894792.1 DUF1797 family protein -
  EL147_RS03475 (NCTC13786_00696) clpE 722033..724315 (+) 2283 WP_007894778.1 ATP-dependent Clp protease ATP-binding subunit Regulator
  EL147_RS03480 (NCTC13786_00697) - 724428..724874 (+) 447 WP_007894611.1 NUDIX hydrolase -
  EL147_RS03485 (NCTC13786_00698) - 724924..725226 (+) 303 WP_007894725.1 DUF1827 family protein -
  EL147_RS03490 (NCTC13786_00699) ileS 725618..728419 (-) 2802 WP_007894816.1 isoleucine--tRNA ligase -

Sequence

Protein


Download         Length: 760 a.a.        Molecular weight: 84303.39 Da        Isoelectric Point: 5.1546

>NTDB_id=1121994 EL147_RS03475 WP_007894778.1 722033..724315(+) (clpE) [Streptococcus pseudoporcinus strain NCTC13786]
MLCQNCKLNEASIHLYANVNGTQKQIDLCQNCYQIMKTDANNSILGGMRSKSQNQNDSLNPLFDDFFGDLNNFRAFGNLP
NTPPTQTGRQNGGGSGGGNNRNGQGAVSGQNTKREPGLLEEFGINVTDIARNGDIDPVIGRDEEIIRVIEILNRRTKNNP
VLIGEPGVGKTAVVEGLAQKIVDGSVPHKLQHKEVIRLDVVSLVQGTGIRGQFEERMQKLMEEIRNRQDVILFIDEIHEI
VGAGTAGDGNMDAGNILKPALARGELQLVGATTLNEYRIIEKDAALERRMQPVKVDEPSVEETITILKGIQAKYEDYHHV
KYSQDAIEAAANLSNRYIQDRFLPDKAIDLLDEAGSKLNLTLNFVDPKEIDKRLVEAENLKAQATRDEDFERAAYFRDQI
AKYKELQTQKVDDQDTPIITEKTIEAIVEQKTNIPVGDLKEKEQSQLVNLSDDLKAHVIGQDAAVDKIAKAIRRNRVGLG
SPNRPIGSFLFVGPTGVGKTELSKQLAIELFGSADNMIRFDMSEYMEKHAVAKLVGAPPGYVGYEEAGQLTEKVRRNPYS
LILLDEVEKAHPDVMHMFLQVLDDGRLTDGQGRTVSFKDTIIIMTSNAGTGKVEASVGFGAAREGRTNSVMGELSNYFSP
EFMNRFDGIIEFQALSKEHLLQIVDLMLTDVNSRLAYNNIHLDVTDKVKEKLVDLGYDAKMGARPLRRTIQDHIEDAITD
YYLENPTEKNLKAMLSSNGNIVIKSAKKLDKAQSVSQQKD

Nucleotide


Download         Length: 2283 bp        

>NTDB_id=1121994 EL147_RS03475 WP_007894778.1 722033..724315(+) (clpE) [Streptococcus pseudoporcinus strain NCTC13786]
ATGCTTTGTCAAAACTGTAAATTAAATGAAGCCTCTATTCACCTATACGCTAACGTGAATGGGACACAAAAGCAGATTGA
TCTTTGTCAAAACTGTTATCAAATTATGAAGACTGACGCAAATAACTCGATTCTGGGTGGGATGCGTTCTAAATCCCAAA
ATCAAAATGATTCTTTGAATCCTTTATTTGACGATTTCTTTGGTGACCTCAACAACTTCAGAGCTTTTGGGAACTTGCCA
AATACACCCCCAACTCAGACTGGTAGACAAAATGGTGGAGGATCCGGCGGAGGCAACAACCGTAACGGCCAAGGAGCAGT
ATCTGGGCAAAATACCAAAAGAGAACCCGGTCTCCTTGAAGAGTTTGGTATTAACGTGACTGATATAGCAAGAAATGGTG
ATATTGATCCTGTCATTGGTCGCGATGAGGAAATCATTCGTGTCATTGAGATTTTAAATCGACGAACCAAGAATAATCCT
GTCTTAATTGGTGAACCGGGTGTCGGTAAAACGGCAGTCGTAGAAGGTTTAGCCCAAAAAATCGTTGATGGTAGTGTTCC
TCATAAACTGCAACATAAAGAGGTGATTCGTTTGGACGTGGTTAGTCTAGTTCAGGGGACTGGTATTCGCGGACAATTTG
AAGAACGTATGCAAAAATTGATGGAAGAAATTCGTAATCGTCAAGATGTTATTCTCTTCATTGATGAGATTCATGAAATT
GTTGGTGCCGGTACTGCTGGGGATGGCAATATGGATGCTGGAAATATCTTAAAACCAGCCTTAGCTCGTGGGGAATTACA
GCTGGTTGGTGCAACAACACTCAACGAATACCGGATCATTGAAAAAGATGCTGCCTTAGAGCGTCGGATGCAACCTGTTA
AGGTCGATGAGCCTTCTGTGGAAGAAACCATTACTATTCTTAAAGGTATTCAAGCCAAATACGAAGACTATCATCATGTT
AAATACAGCCAAGATGCTATCGAAGCAGCTGCTAACTTATCGAATCGTTATATTCAAGATCGATTCTTACCGGATAAAGC
TATTGACTTGCTTGATGAAGCTGGATCAAAGCTGAATTTAACGCTTAACTTTGTTGACCCTAAAGAAATTGATAAACGAT
TAGTGGAAGCTGAAAATTTAAAAGCGCAAGCCACTCGTGATGAAGACTTTGAACGCGCAGCCTATTTCCGCGATCAAATT
GCTAAATACAAGGAGCTCCAAACTCAAAAGGTAGACGATCAAGATACTCCTATTATTACTGAAAAGACTATTGAAGCAAT
TGTTGAGCAAAAAACCAATATTCCTGTTGGTGATCTCAAAGAAAAAGAGCAATCTCAGTTAGTCAATCTTTCAGATGATT
TGAAAGCTCATGTAATTGGTCAAGATGCTGCTGTTGATAAAATTGCTAAGGCTATTCGTCGCAATCGTGTTGGTTTAGGT
AGCCCAAATCGACCGATTGGATCTTTCCTCTTTGTGGGCCCGACTGGGGTAGGGAAGACGGAACTCTCTAAACAATTAGC
TATTGAACTCTTCGGTTCAGCTGATAATATGATTCGTTTTGATATGTCTGAATATATGGAAAAGCACGCTGTTGCTAAGT
TAGTGGGAGCCCCTCCAGGATATGTCGGTTATGAAGAAGCCGGTCAATTAACAGAAAAAGTTAGACGAAATCCTTATTCA
CTGATATTATTGGACGAAGTTGAAAAAGCTCACCCTGACGTTATGCATATGTTCCTTCAAGTTTTAGATGATGGTCGGCT
AACTGATGGACAAGGGCGGACAGTCAGCTTTAAAGATACTATTATTATCATGACATCAAATGCAGGTACTGGCAAAGTTG
AAGCCTCCGTTGGTTTTGGGGCTGCACGCGAAGGACGTACCAATTCTGTTATGGGAGAATTAAGCAATTACTTTAGCCCA
GAATTTATGAATCGTTTTGATGGTATTATTGAGTTCCAAGCATTAAGCAAAGAACATTTATTACAGATTGTTGATCTAAT
GTTGACTGATGTCAATAGCCGTTTAGCCTATAACAATATTCACCTTGACGTCACAGACAAGGTGAAGGAAAAATTAGTTG
ATCTCGGCTATGACGCTAAGATGGGGGCCCGTCCACTTAGAAGAACGATTCAAGATCATATCGAAGATGCCATTACAGAC
TATTATCTTGAAAATCCGACTGAGAAGAACTTAAAGGCCATGTTGTCAAGTAATGGTAATATAGTGATTAAAAGCGCCAA
AAAACTCGATAAAGCGCAATCTGTTTCTCAGCAAAAAGACTAA

Domains

Predicted by InterproScan.

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(655-730)

AAA domain (Cdc48 subfamily) (AAA_2)

(484-647)

AAA lid domain (AAA_lid_9)

(299-396)

ATPase family associated with various cellular activities (AAA) (AAA)

(161-279)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB G5K907

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpE Streptococcus mutans UA159

84.84

98.947

0.839
  clpE Streptococcus pneumoniae Rx1

82.626

99.211

0.82
  clpE Streptococcus pneumoniae D39

82.626

99.211

0.82
  clpE Streptococcus pneumoniae R6

82.626

99.211

0.82
  clpE Streptococcus pneumoniae TIGR4

82.493

99.211

0.818
  clpC Lactococcus lactis subsp. cremoris KW2

76.287

97.105

0.741
  clpC Bacillus subtilis subsp. subtilis str. 168

51.493

88.158

0.454
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

47.687

82.5

0.393
  clpC Streptococcus pneumoniae Rx1

48.214

81.053

0.391
  clpC Streptococcus pneumoniae D39

48.214

81.053

0.391
  clpC Streptococcus pneumoniae TIGR4

48.052

81.053

0.389
  clpC Streptococcus mutans UA159

47.249

81.316

0.384
  clpC Streptococcus thermophilus LMD-9

46.56

82.237

0.383
  clpC Streptococcus thermophilus LMG 18311

46.24

82.237

0.38

Multiple sequence alignment