Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpE   Type   Regulator
Locus tag   EL140_RS02965 Genome accession   NZ_LR134336
Coordinates   587920..590178 (-) Length   752 a.a.
NCBI ID   WP_000882482.1    Uniprot ID   -
Organism   Streptococcus oralis ATCC 35037 strain NCTC 11427     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 582920..595178
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL140_RS02940 (NCTC11427_00576) metK 584061..585257 (+) 1197 WP_000003921.1 methionine adenosyltransferase -
  EL140_RS02945 (NCTC11427_00577) - 585319..585618 (-) 300 WP_000767207.1 DUF1827 family protein -
  EL140_RS02950 (NCTC11427_00578) - 585677..586129 (-) 453 WP_000013089.1 NUDIX hydrolase -
  EL140_RS02955 (NCTC11427_00579) - 586306..587208 (+) 903 WP_000841074.1 helix-turn-helix transcriptional regulator -
  EL140_RS02960 (NCTC11427_00580) - 587263..587877 (+) 615 WP_000873097.1 GyrI-like domain-containing protein -
  EL140_RS02965 (NCTC11427_00581) clpE 587920..590178 (-) 2259 WP_000882482.1 ATP-dependent Clp protease ATP-binding subunit Regulator
  EL140_RS02970 (NCTC11427_00582) - 590418..590648 (-) 231 WP_000443577.1 DUF1797 family protein -
  EL140_RS02975 (NCTC11427_00583) - 590840..591523 (+) 684 WP_001011622.1 amino acid ABC transporter permease -
  EL140_RS02980 (NCTC11427_00584) - 591523..592257 (+) 735 WP_000140925.1 amino acid ABC transporter ATP-binding protein -
  EL140_RS02985 (NCTC11427_00585) - 592291..592611 (+) 321 WP_000168538.1 TfoX/Sxy family protein -
  EL140_RS02990 (NCTC11427_00586) - 592760..593617 (+) 858 WP_000057225.1 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase -
  EL140_RS02995 (NCTC11427_00587) - 593622..594395 (+) 774 WP_000673607.1 HAD hydrolase family protein -

Sequence

Protein


Download         Length: 752 a.a.        Molecular weight: 83897.29 Da        Isoelectric Point: 5.0311

>NTDB_id=1121840 EL140_RS02965 WP_000882482.1 587920..590178(-) (clpE) [Streptococcus oralis ATCC 35037 strain NCTC 11427]
MLCQNCKINDSTIHLYTNINGQQKQIDLCQNCYKIIKTDPNNTLFKGMTDLNNHDFDPFGDFFNDLNNFKPSSNNVPPTQ
SGGGYGGNGGYGPQNRGPLQTPPSQERGLLEEYGINITEIARRGDIDPVIGRDEEIIRVIEILNRRTKNNPVLIGEPGVG
KTAVVEGLAQKIVDGDVPHKLQGKQVIRLDVVSLVQGTGIRGQFEERMQKLMEEIRKREDIILFIDEIHEIVGAGSAGDG
NMDAGNILKPALARGELQMVGATTLNEYRIIEKDAALERRMQPVKVDEPTVEETIIILKGVQKKYEDYHHVKYTDAAIEA
AANLSNRYIQDRFLPDKAIDLLDEAGSKMNLTLNFVDPKVIDQRLIEAENLKAQATREEDFEKAAYFRDQIAKYKEMQKN
KVTDQDTPIISEKTIEHIIEQKTNIPVGELKEKEQSQLIHLADDLKAHVIGQDEAVDKIAKAIRRNRVGLGTPNRPIGSF
LFVGPTGVGKTELSKQLAIELFGSADSMIRFDMSEYMEKHSVAKLVGAPPGYVGYDEAGQLTEKVRRNPYSLILLDEVEK
AHPDVMHMFLQVLDDGRLTDGQGRTVSFKDAIIIMTSNAGTGKAEASVGFGAAREGRTNSVLGELGNFFSPEFMNRFDGI
IEFKPLSKDNLLQIVELMLADVNKRLSSNNIHLDVTDKVKEKLVDLGYDPKMGARPLRRTIQDYIEDAITDYYLENPSEK
ALKAVMTSNGNIQIKSAKKTEKTEEIASEIEE

Nucleotide


Download         Length: 2259 bp        

>NTDB_id=1121840 EL140_RS02965 WP_000882482.1 587920..590178(-) (clpE) [Streptococcus oralis ATCC 35037 strain NCTC 11427]
ATGCTCTGTCAAAACTGTAAAATAAACGACTCAACAATTCATCTGTATACCAATATCAATGGACAGCAAAAGCAAATTGA
TCTCTGTCAAAATTGCTATAAAATTATCAAAACAGATCCAAATAATACCCTCTTTAAAGGAATGACTGACTTAAACAATC
ATGACTTTGATCCTTTCGGCGACTTTTTCAATGATTTGAACAATTTCAAACCTTCTTCTAATAACGTCCCTCCAACTCAA
TCTGGTGGGGGATACGGAGGAAACGGCGGTTATGGGCCTCAAAACCGCGGTCCACTTCAAACACCTCCTAGCCAAGAAAG
AGGACTCCTAGAGGAATACGGTATCAATATTACTGAGATTGCTCGTCGGGGAGATATTGACCCTGTTATCGGTCGAGATG
AGGAGATTATCCGTGTTATCGAAATCCTCAACCGAAGAACCAAGAACAATCCTGTCCTTATCGGAGAACCAGGTGTTGGT
AAAACAGCCGTTGTTGAAGGTTTAGCTCAGAAGATTGTCGATGGCGATGTTCCTCATAAACTCCAAGGCAAGCAGGTCAT
CCGTCTGGATGTGGTCAGTCTAGTCCAAGGAACAGGGATTCGAGGCCAATTTGAAGAACGTATGCAAAAGCTCATGGAAG
AAATTCGCAAACGCGAGGACATCATCCTCTTTATCGACGAAATCCATGAAATTGTTGGTGCAGGGTCAGCAGGTGATGGC
AATATGGATGCAGGCAATATCCTTAAACCAGCCCTTGCCCGTGGTGAATTACAAATGGTCGGTGCCACTACTCTCAATGA
ATACCGCATCATTGAAAAAGATGCTGCCCTCGAGCGCCGTATGCAGCCTGTCAAGGTAGATGAACCAACTGTCGAAGAAA
CCATTATCATCCTTAAAGGGGTTCAAAAGAAATACGAAGACTACCATCACGTCAAGTATACTGATGCTGCTATCGAAGCT
GCTGCAAATCTTTCCAATCGCTATATCCAAGATCGCTTCTTGCCAGACAAGGCTATTGACCTGTTAGATGAAGCTGGTTC
TAAGATGAATCTGACACTGAACTTTGTTGATCCTAAAGTGATTGACCAGCGTTTAATTGAAGCTGAGAATCTCAAGGCTC
AGGCTACTCGAGAGGAAGACTTTGAAAAGGCTGCCTATTTCCGCGATCAGATTGCCAAGTACAAGGAAATGCAGAAAAAC
AAGGTGACTGACCAGGATACTCCTATCATTAGCGAGAAAACCATTGAGCATATCATTGAGCAGAAAACTAATATCCCTGT
TGGGGAGCTAAAAGAAAAAGAACAGTCTCAGCTTATCCATCTAGCAGACGACCTCAAGGCCCATGTTATCGGACAAGATG
AAGCTGTCGATAAGATTGCCAAGGCCATCCGTCGTAATCGTGTTGGTCTTGGAACTCCTAACCGCCCAATCGGAAGTTTC
CTCTTTGTCGGACCAACTGGTGTCGGTAAGACAGAACTTTCCAAACAACTAGCCATTGAGCTCTTTGGTTCTGCTGACAG
CATGATTCGCTTTGATATGAGTGAATACATGGAAAAACACAGTGTGGCTAAATTAGTCGGAGCTCCTCCAGGTTATGTCG
GCTATGATGAAGCTGGTCAATTAACGGAAAAAGTTCGTCGCAATCCTTACTCACTCATCCTTCTCGATGAAGTCGAAAAA
GCCCATCCAGATGTGATGCACATGTTCCTTCAAGTCTTGGACGATGGTCGTTTGACAGATGGGCAAGGACGAACAGTTAG
CTTTAAGGATGCTATCATTATTATGACCTCAAATGCCGGTACGGGTAAGGCCGAAGCCAGTGTTGGGTTTGGAGCTGCTC
GTGAAGGACGTACTAATTCTGTTCTTGGTGAACTCGGTAACTTCTTTAGTCCTGAGTTTATGAACCGTTTTGACGGCATC
ATCGAATTTAAACCTCTCAGCAAGGACAACCTTCTCCAAATCGTCGAACTCATGCTAGCGGATGTCAACAAACGCCTCTC
TAGCAACAATATCCACCTCGATGTGACAGACAAGGTCAAGGAAAAATTGGTTGACTTAGGTTATGATCCAAAAATGGGGG
CTCGCCCACTCCGCCGCACCATTCAAGACTATATCGAGGATGCTATCACAGACTACTACCTTGAAAACCCAAGTGAGAAA
GCCCTCAAAGCAGTCATGACAAGCAATGGCAATATTCAAATCAAATCTGCCAAAAAAACTGAGAAAACAGAAGAGATTGC
TTCTGAAATAGAAGAATAA

Domains

Predicted by InterproScan.

ATPase family associated with various cellular activities (AAA) (AAA)

(152-271)

AAA lid domain (AAA_lid_9)

(290-387)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(646-721)

AAA domain (Cdc48 subfamily) (AAA_2)

(475-638)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpE Streptococcus pneumoniae Rx1

94.758

98.936

0.937
  clpE Streptococcus pneumoniae D39

94.758

98.936

0.937
  clpE Streptococcus pneumoniae R6

94.758

98.936

0.937
  clpE Streptococcus pneumoniae TIGR4

94.624

98.936

0.936
  clpE Streptococcus mutans UA159

82.891

100

0.831
  clpC Lactococcus lactis subsp. cremoris KW2

75.762

100

0.761
  clpC Bacillus subtilis subsp. subtilis str. 168

52.462

86.436

0.453
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

48.485

83.378

0.404
  clpC Streptococcus thermophilus LMD-9

46.91

83.91

0.394
  clpC Streptococcus thermophilus LMG 18311

46.667

83.777

0.391
  clpC Streptococcus mutans UA159

46.508

83.777

0.39
  clpC Streptococcus pneumoniae TIGR4

47.182

82.58

0.39
  clpC Streptococcus pneumoniae Rx1

47.182

82.58

0.39
  clpC Streptococcus pneumoniae D39

47.182

82.58

0.39

Multiple sequence alignment